August 03, 2011 12:15 PM Eastern Daylight Time 

DUBLIN–(BUSINESS WIRE)–Research and Markets (researchandmarkets.com/research/68be38/2011_annual_report) has announced the addition of the “2011 Annual Report on Prostate Diseases” report to their offering.

Prostate disorders usually develop after age 50, but some men experience them at a younger age. the three most common conditions are prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer. Although they share some of the same symptoms, they are very different. Treatments vary, too. For example, two men with prostate cancer might opt for treatments as divergent as radical surgery and doing nothing at all. Even getting screened for prostate cancer, which seems like it would be a no-brainer, requires thoughtful consideration. That’s because most men usually feel compelled to undergo treatment if cancer is diagnosed often without knowing for certain whether the cancer would ever cause problems during their lifetime. By doing so, they risk complications like impotence and incontinence that can dramatically undermine quality of life.

whether you are considering medication for BPH or erectile dysfunction, or debating between radiation therapy and surgery for prostate cancer, you need to review your options carefully. this report, which provides an objective assessment of the risks and benefits of various procedures, can help. more than a primer on the most common prostate conditions, this unique publication includes summaries of that latest research, roundtable discussions with experts at the forefront of prostate cancer research; assessments of different therapies from Harvard Medical School doctors; interviews with patients about their treatment decisions; and physicians’ answers to questions posed by patients. it also includes helpful tips on managing and treating erectile dysfunction and impotence caused by prostate disease therapies.

Prepared by the editors of Harvard Health Publications in consultation with Marc B. Garnick, M.D., Clinical Professor of Medicine, Harvard Medical School, and Hematology/Oncology Division, Beth Israel Deaconess Medical Center.

Key Topics Covered:

• a year of advances and breakthroughs in prostate disease
• Monitoring prostate health
• Prostate enlargement (benign prostatic hyperplasia)
• Inflammation of the prostate (prostatitis)
• Prostate cancer: What you need to know at every stage of the disease
• Erectile dysfunction and urinary incontinence
• Take charge of your condition

For more information visit researchandmarkets.com/research/68be38/2011_annual_report

18th April, 2011 – Posted by health news –

Prostate enlargement or benign prostatic hyperplasia (BPH) is really a common component of any guy reaching his 50s. the symptoms of this condition might differ, but many are afflicted by the discomfort they bring. Whether or not your situation brings gentle or severe symptoms, these should all be understood to stop complications which are more severe.

The symptoms of benign prostate enlargement or benign prostatic hyperplasia are often triggered because of the bladder slowly shedding its capability. when this occurs, symptoms like the feeling of incompletely emptying the bladder are encountered. These benign prostatic hyperplasia indicators differ, although symptoms like more constant urinating, urgency of dribbling of urine, and interrupted weak flow of urine are common in varying severities of the condition.

The measurement of your prostate doesn’t always determine how severe the condition is. Males having bigger growth in prostate measurement might encounter milder symptoms than these with little improvement in the prostate’s volume.

There might also be cases the individual experiencing benign prostatic hyperplasia doesn’t really feel any obstruction in his urine flow till it becomes severe, totally blocking the urine to flush out. This is referred to as an acute urinary retention, which occurs when medicines meant for allergies, like decongestants, are taken.

This medicine might cause the opening of your bladder to get relaxed, which results in urine remaining inside the organ. if there is partial obstruction, this could be worsened by drinking alcohol, staying in cold locations, or being stagnant at a long time.

Understanding the symptoms of prostate enlargement or benign prostatic hyperplasia is important. most cases that a guy experiences the symptoms indicate the presence of your condition. however, there might also be uncommon cases of the symptoms indicating prostate cancer, which may only be ruled out by your doctor.

Once the symptoms of prostate enlargement become severe, numerous issues in the urinary tract will probably be encountered. Urine retention might result in infection of your urinary tract, bladder stones, incontinence (being unable to control urine flow), and even kidney failure. Remedies for benign prostatic hyperplasia might become useless in case your bladder becomes broken completely.

Once you see 1 or more of your symptoms of prostate enlargement, do not hesitate to visit your physician instantly. This may help stop the indicators from aggravating and damaging your urinary tract.

Going for your physician once a yr significantly helps as your condition could be monitored carefully and might be treated before it becomes even worse. Recognizing these symptoms of benign prostatic hyperplasia will let you know when to look for treatment to decrease the discomforts it brings, and even get rid of the condition completely. Source:BPH medications

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avoid certain foods can reduce the symptoms of BPH

When dealing with problems and symptoms of an enlarged prostate or benign prostatic hyperplasia (BPH), it seems that everyone is ready to propose something new for you to take. Add this supplement to your diet. try this new drug. That’s all for adding

there is another option. Eliminate certain foods from your diet. although a healthy diet can not cure an enlarged prostate, the right balance of foods can reduce outbreaks of BPH symptoms.during his own struggle with the symptoms of an enlarged prostate, R. Rosenthal began to follow his diet. through this process, he discovered a pattern of symptom outbreaks following consumption of certain foods. Rosenthal began looking for these foods and found that tyramine and other vasoactive amines triggered its vasoactive amines symptoms.because occur naturally in foods, Rosenthal found that the best way to reduce symptoms was reduce its consumption of foods with amines. he also discovered that monosodium glutamate, commonly known as MSG, is added to many foods during the manufacturing process, could trigger the symptoms of BPH.

Rosenthal then compiled a list of foods to avoid to reduce symptoms of outbreaks of BPH symptoms. he was able to break these foods into different categories, including dairy products, fruits, vegetables, protein, fermented foods, drinks, soups, sauces and

After learning that the food was not the only trigger for her. symptoms of BPH, Rosenthal sought other environmental factors that could initiate an outbreak of symptoms. Surprisingly, he found a common ingredient in many household cleaners.

Once removed Rosenthal specific foods from your diet and avoid environmental factors, it has succeeded in containing the outbreak of symptoms. As mentioned previously, a change in diet can not cure an enlarged prostate, but it can make life with an enlarged prostate more bearable.

One of the biggest problems facing men with prostate illness, specifically cancer, is that symptoms are quite mild (or nonexistent) until it is in an advanced stage.

The most common screening mechanism is through a prostate specific antigen blood test, or PSA for short, which can often pick up on potential problems before symptoms are present. however, many men do not elect to have the test performed, which leaves them vulnerable to damaging, and potentially deadly, prostate illness.

One of the earliest signs of prostate problems is the need to urinate frequently, maintaining a constant flow of urine, and/or difficulty beginning the urination process. Pain may also be present, including blood in the urine.

The sexual experience may be dampened as well, and you may experience difficulty obtaining or maintaining an erection. Ejaculation may be painful, and semen may contain blood.

If any of the above symptoms appear, it would be quite evident that a prostate problem is at hand, though it does not necessarily signify any type of cancer. An enlargement of the prostate gland, a medical condition known as benign prostatic hyperplasia (BPH), could be the instigating factor, and is easily treatable. however, even with this benign condition, treatment can become more problematic if overly ignored.

On the other hand, these problems could be symptomatic of prostate cancer. if diagnosed in its early stages, this condition has a very high treatment success rate. however, once in the more advanced stages, after the cancer spreads beyond the prostate gland itself, it becomes increasingly difficult to manage. to be perfectly honest, once it moves past this threshold, a cure may not be possible, and the only treatment options available would be to slow its progression and hopefully control the symptoms.

The mildness of prostate troubles, at least at their onset, are often overlooked, since they typically don’t affect your day-to-day life, and are often attributed to aging. however, prostate cancer kills tens of thousands of men every year, which is entirely preventable if detected in its early stages. if you are currently encountering any of these symptoms or are 40 years of age or older, talk to your doctor about running a prostate screen during your next routine examination. It may be simple, but it also may save your life.

02.07.2011– February 7, 2011 (Cincinnati, Ohio) — Results of two Phase 1 clinical trials of S-equol (AUS-131) were published in the February issue of Menopause: The Journal of the North American Menopause Society. this first-in-class, nonsteroidal, nonhormonal estrogen receptor ? (ER?) agonist offers a potentially safer alternative to estrogen for the treatment of menopausal symptoms. As part of a drug development program, these studies were the first to investigate AUS-131 in humans. Results demonstrated a favorable safety and pharmacokinetic profile for AUS-131, and have allowed the company to proceed to Phase 2 clinical trials, which will be completed in Q3 2011. these studies evaluated the pharmacokinetics and tolerability of single and multiple oral doses of AUS-131 in healthy volunteers. these studies also established the doses for proof-of-concept Phase 2 studies investigating AUS-131 as a treatment for postmenopausal women with vasomotor symptoms (VMS), commonly referred to as hot flashes. Results also support Ausio’s development of AUS-131 as a treatment option to inhibit prostate cell growth in men with benign prostatic hyperplasia (BPH). The full paper is available at: journals.lww.com/menopausejournal/Abstract/2011/02000/Single_dose_and_steady_statepharmacokinetic.15.aspx “One of the compelling reasons for developing S-equol as a pharmaceutical product is that women are reluctant to take estrogens for their menopausal symptoms” said Richard Jackson, PhD, Ausio Pharmaceuticals, LLC, President and CEO, and the study’s lead author. “Based on the Phase 1 studies, AUS-131 offers an oral medication that safely delivers therapeutic levels of S-equol, which may benefit patients with a variety of diseases and conditions.” History of Treatment of Menopausal Symptoms and Significance of S-Equol whereas hormone therapy (HT) has been the therapy of choice for the management of menopausal symptoms in women, the Women’s Health Initiative has shown that HT has been associated with increased risk of invasive breast cancer, coronary heart disease, stroke, and deep vein thrombosis. this increased risk is associated with the abundance and prominent role of the estrogen receptor ? (ER?) in the breast, uterus, and endothelium in the cardiovascular system. Alternative treatments for VMS have included serotonin, norepinephrine, mixed reuptake inhibitors, and botanicals such as soy products and black cohosh, but these treatments have both efficacy and safety issues. beyond botanicals, purified, nonsteroidal isoflavones found in soy—genistein, daidzein, and glycitien—have been studied for the treatment of chronic diseases in the aging population, including, among others, VMS in postmenopausal women, with limited success. Daidzein is further biotransformed to the isoflavan S-equol by the intestinal bacteria flora of certain individuals, particularly Asians. Published reports show that patients who demonstrate the health benefits of soy are those who are equol producers. Cincinnati-based Ausio Pharmaceuticals, LLC has developed a patented chemical process for the synthesis of S-equol that allows for large-scale production of pure GMP-quality S-equol to conduct clinical trials. About the Studies two randomized, double-blind, placebo-controlled clinical trials were performed in healthy volunteers: a single-rising dose study in 61 participants and a 14-day repeat-dose study in 40 participants. Safety, tolerability, and pharmacokinetics of AUS-131 were assessed in both men and women. AUS-131 was well-tolerated by all participants with no significant drug-related adverse events at doses several-fold higher than the expected therapeutic range. Food decreased maximal plasma concentration but did not significantly affect overall exposure to the drug. AUS-131 was readily absorbed with a steady-state level of S-equol achieved after the first day of twice-daily dosing. The pharmacokinetics of the drug were linear with dose and showed that the drug was readily cleared from the body. Subjects receiving the lower doses of AUS-131 achieved plasma levels of S-equol equivalent to those that researchers have associated with the health benefits of ingestion of soy. these studies in healthy participants also provided the first report of plasma and urine levels of unconjugated S-equol after oral dosing using a recently published highly sensitive method. Results from Phase 1 studies provided dosing information for the ongoing international, multicenter Phase 2a efficacy trials in patients with VMS and BPH. About AUS-131 AUS-131 is a first-in-class, nonsteroidal, nonhormonal, selective ER? agonist that has the potential to provide the therapeutic benefits that researchers have attributed to soy ingestion. Importantly, results to date show that the compound has an excellent safety profile. AUS-131 is pure, synthetic S-equol, which is a soy isoflavone that is naturally produced in a small percent of individuals in the US after ingestion of soy. this molecule is being evaluated for a wide range of indications, including menopausal symptoms, BPH, osteoporosis, and topical applications. About Vasomotor Symptoms In the US, there are more than 40 million postmenopausal women. More than 70% of these women experience hot flashes. The major products available to treat these symptoms are estrogens, which have current US sales of $1.8 billion, despite the risks associated with their use. The results of the Women’s Health Initiative study showing increased risk of breast cancer, cardiovascular events, stroke, and venous thrombosis with long-term estrogen-progestin therapy have dramatically decreased the use of estrogen therapy and increased the market opportunity for new VMS therapy with an ER? agonist, such as the S-equol product, AUS-131. About Ausio Pharmaceuticals Ausio Pharmaceuticals, LLC, is a private biotechnology development company focused on the advancement of safe and effective medicines for the aging population. Ausio was founded in 2006 by Richard Jackson, PhD based on technologies licensed from the Australian Health and Nutrition Association Ltd, NSW, Australia, and Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio. The company has garnered a strong patent position for its lead compound, AUS 131. it has rapidly developed AUS-131 by working with excellent service providers. Ausio’s strategic goal is to collaborate with international pharmaceutical partners for AUS-131 in the US and other markets worldwide. for further information on Ausio, please visit the company’s website at ausiopharma.com. CONTACT: Iris Shaffer (708) 799-6284

Benign prostatic hyperplasia (BPH) can’t be cured, so therapy focuses on lowering your symptoms. Treatment is based on how severe your symptoms are, how much they bother you, and no matter if you’ve complications.

Deciding the best way to treat BPH is significantly influenced by how bothersome your symptoms are. the American Urological Association (AUA) symptom index is an interactive questionnaire that may help you tell how bad your symptoms are and measure how well your treatment is operating. This questionnaire ranks the severity of the symptoms on a numerical scale. the higher the quantity, the extra you will be bothered by your symptoms and the much more aggressive you may want to be inside your therapy.

Preliminary treatment

The American Urological Association (AUA) makes the following treatment recommendations for benign prostatic hyperplasia (BPH) based on the severity of one’s symptoms.4

Symptoms that are mild or that don’t bother you (AUA score of 0 to 7) might be best treated by watchful waiting. This indicates you could make tiny changes to your way of life to control your symptoms, but you usually do not take medicines or have surgery. You’ve common checkups to be certain your symptoms usually are not getting worse.the therapy of moderate to severe symptoms (AUA score of 8 or much more) depends on how much you are bothered by them. If the symptoms usually are not greatly affecting your top quality of life, you might pick watchful waiting or therapy with medicine. If the symptoms are bothersome or you want much more aggressive therapy, you might be supplied surgery or less invasive therapies, such as transurethral microwave therapy (TUMT) or transurethral needle ablation (TUNA).Severe symptoms, including ongoing inability to urinate, bladder stones, kidney harm, or ongoing blood in your urine, needs to be treated with surgery.You’ll find some items it is possible to do that might assist decrease how much BPH affects your quality of life.

Do not try to rush your urination. Attempt to relax while utilizing the bathroom.Spread your fluid intake throughout the day. Limit fluid intake in the evening if you typically wake up at night to urinate.If doable, stay away from medicines that make your symptoms worse.think about trying an herbal therapy for BPH, such as saw palmetto or beta-sitosterol. Speak together with your doctor prior to beginning any herbal therapy.

If you suffer from bladder infection symptoms or enlarged prostate symptoms you might consider visiting our site, where you will find information and effective treatment.