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	<title>Symptom Advice .com &#187; cohorts</title>
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		<title>Common genetic cause of autism, epilepsy</title>
		<link>http://symptomadvice.com/common-genetic-cause-of-autism-epilepsy/</link>
		<comments>http://symptomadvice.com/common-genetic-cause-of-autism-epilepsy/#comments</comments>
		<pubDate>Sat, 16 Apr 2011 14:00:16 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[autism symptoms]]></category>
		<category><![CDATA[cohorts]]></category>
		<category><![CDATA[deregulation]]></category>
		<category><![CDATA[epilepsy]]></category>
		<category><![CDATA[morbidity]]></category>
		<category><![CDATA[mutations]]></category>

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		<description><![CDATA[MONTREAL, April 8 (UPI) &#8212; Researchers &#105;&#110; Canada &#115;&#097;&#121; they discovered a new gene that predisposes people &#116;&#111; &#098;&#111;&#116;&#104; autism &#097;&#110;&#100; epilepsy. Study leader Dr. Patrick Cossette &#111;&#102; the Universite de Montreal &#097;&#110;&#100; the research team &#102;&#111;&#117;&#110;&#100; a severe mutation &#111;&#102; the synapsin gene &#8212; SYN1 &#8212; &#105;&#110; &#097;&#108;&#108; members &#111;&#102; a large French-Canadian family [...]]]></description>
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<p>MONTREAL, April 8 (UPI) &#8212; Researchers &#105;&#110; Canada &#115;&#097;&#121; they discovered a new gene that predisposes people &#116;&#111; &#098;&#111;&#116;&#104; autism &#097;&#110;&#100; epilepsy.</p>
<p>Study leader Dr. Patrick Cossette &#111;&#102; the Universite de Montreal &#097;&#110;&#100; the research team &#102;&#111;&#117;&#110;&#100; a severe mutation &#111;&#102; the synapsin gene &#8212; SYN1 &#8212; &#105;&#110; &#097;&#108;&#108; members &#111;&#102; a large French-Canadian family with members suffering from epilepsy &#097;&#110;&#100; autism.</p>
<p>The analysis &#111;&#102; two cohorts &#111;&#102; individuals from Quebec &#109;&#097;&#100;&#101; &#105;&#116; possible &#116;&#111; identify other mutations &#105;&#110; the SYN1 gene &#097;&#109;&#111;&#110;&#103; 1 percent with autism &#097;&#110;&#100; 3.5 percent with epilepsy, &#119;&#104;&#105;&#108;&#101; &#115;&#101;&#118;&#101;&#114;&#097;&#108; carriers &#111;&#102; the SYN1 mutation displayed symptoms &#111;&#102; &#098;&#111;&#116;&#104; disorders, Cossette said.</p>
<p>&#8220;The results &#115;&#104;&#111;&#119; for the &#102;&#105;&#114;&#115;&#116; time the role &#111;&#102; the SYN1 gene &#105;&#110; autism, &#105;&#110; addition &#116;&#111; epilepsy, &#097;&#110;&#100; strengthen the hypothesis that a deregulation &#111;&#102; the function &#111;&#102; synapse &#098;&#101;&#099;&#097;&#117;&#115;&#101; &#111;&#102; this mutation is the cause &#111;&#102; &#098;&#111;&#116;&#104; diseases,&#8221; Cossette &#115;&#097;&#121;&#115; &#105;&#110; a statement. &#8220;Until now, no other genetic study &#111;&#102; humans &#104;&#097;&#115; &#109;&#097;&#100;&#101; this demonstration.&#8221;</p>
<p>The study, published online &#105;&#110; Human Molecular Genetics, &#115;&#097;&#121;&#115; the different forms &#111;&#102; autism are often genetic &#105;&#110; origin &#097;&#110;&#100; &#110;&#101;&#097;&#114;&#108;&#121; one-third &#111;&#102; people with autism &#097;&#108;&#115;&#111; suffer from epilepsy, &#098;&#117;&#116; the reason for this co-morbidity is unknown.</p></p>
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