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	<title>Symptom Advice .com &#187; columbia university</title>
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		<title>Ally Hilfiger, Richard Gerstner, Dr. Karen Newell to be Honored at the Time for Lyme Gala on April 2, 2011</title>
		<link>http://symptomadvice.com/ally-hilfiger-richard-gerstner-dr-karen-newell-to-be-honored-at-the-time-for-lyme-gala-on-april-2-2011/</link>
		<comments>http://symptomadvice.com/ally-hilfiger-richard-gerstner-dr-karen-newell-to-be-honored-at-the-time-for-lyme-gala-on-april-2-2011/#comments</comments>
		<pubDate>Wed, 23 Mar 2011 21:00:10 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[lyme symptoms]]></category>
		<category><![CDATA[ally hilfiger]]></category>
		<category><![CDATA[columbia university]]></category>
		<category><![CDATA[lyme disease]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/ally-hilfiger-richard-gerstner-dr-karen-newell-to-be-honored-at-the-time-for-lyme-gala-on-april-2-2011/</guid>
		<description><![CDATA[Posted on: Sunday, 6 March 2011, 00:02 CST Proceeds &#102;&#114;&#111;&#109; the event &#119;&#105;&#108;&#108; &#098;&#101; used to fund &#105;&#109;&#112;&#111;&#114;&#116;&#097;&#110;&#116; research projects, medical symposiums and education. &#115;&#105;&#110;&#099;&#101; the commencement of Time &#102;&#111;&#114; Lyme’s fundraising efforts in 2001, it &#104;&#097;&#115; raised nearly $5 million and partnered &#119;&#105;&#116;&#104; Columbia University Medical Center to create its Lyme and Tick-Borne Disease [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/03/1300914010-30.jpg" style="clear:both;clear:both;margin:0 15px 15px 0" />
<p>Posted on: Sunday, 6 March 2011, 00:02 CST </p>
<p><i>Proceeds &#102;&#114;&#111;&#109; the event &#119;&#105;&#108;&#108; &#098;&#101; used to fund &#105;&#109;&#112;&#111;&#114;&#116;&#097;&#110;&#116; research projects, medical symposiums and education. &#115;&#105;&#110;&#099;&#101; the commencement of Time &#102;&#111;&#114; Lyme’s fundraising efforts in 2001, it &#104;&#097;&#115; raised nearly $5 million and partnered &#119;&#105;&#116;&#104; Columbia University Medical Center to create its Lyme and Tick-Borne Disease Research Center.</i></p>
<p>Greenwich, CT (PRWEB) March 4, 2011 </p>
<p> Time &#102;&#111;&#114; Lyme &#119;&#105;&#108;&#108; honor Ally Hilfiger &#119;&#105;&#116;&#104; the Star Light Award and Richard Gerstner and Dr. Karen Newell &#119;&#105;&#116;&#104; the Lauren F. Brooks Hope Award, &#097;&#116; its fundraiser, “Illusions of Lyme,” on April 2 &#097;&#116; the Hilton Hotel in Stamford. Time &#102;&#111;&#114; Lyme is a Greenwich-based non-profit that funds research on Lyme and &#111;&#116;&#104;&#101;&#114; tick-borne diseases.</p>
<p>Hilfiger, 26, daughter of fashion icon and Greenwich resident Tommy Hilfiger, &#114;&#101;&#099;&#101;&#110;&#116;&#108;&#121; launched a new fashion line and is a film producer, actress and reality &#115;&#104;&#111;&#119; star. She’s accomplished &#097;&#108;&#108; this &#100;&#101;&#115;&#112;&#105;&#116;&#101; facing a 19-year battle &#119;&#105;&#116;&#104; Lyme disease.</p>
<p>Time &#102;&#111;&#114; Lyme selected Hilfiger &#102;&#111;&#114; the award because &#115;&#104;&#101; is &#097;&#110; avid spokesperson about the obstacles faced by the thousands of people afflicted &#119;&#105;&#116;&#104; the disease. Faced &#119;&#105;&#116;&#104; a myriad of afflictions, Hilfiger underwent years of misdiagnoses &#102;&#114;&#111;&#109; ‘growing pains‘ to multiple sclerosis.</p>
<p>“We &#097;&#114;&#101; thrilled Ally Hilfiger &#104;&#097;&#115; joined us to help dispel the myth that Lyme symptoms &#097;&#114;&#101; imagined. Thousands of people &#097;&#114;&#101; &#116;&#111;&#108;&#100; that &#116;&#104;&#101;&#105;&#114; symptoms &#097;&#114;&#101; “illusions”, by practitioners who &#097;&#114;&#101; not well enough versed in the disease’s indicators” &#115;&#097;&#105;&#100; Deb Siciliano, a co-founder of Time &#102;&#111;&#114; Lyme.</p>
<p>Also honored &#097;&#116; the gala &#102;&#111;&#114; &#104;&#105;&#115; unfaltering commitment to making strides in the battle &#097;&#103;&#097;&#105;&#110;&#115;&#116; Lyme &#119;&#105;&#108;&#108; &#098;&#101; Richard Gerstner, who faced a long battle &#119;&#105;&#116;&#104; Lyme during &#104;&#105;&#115; tenure &#097;&#116; IBM and &#104;&#105;&#115; subsequent career in the venture capital arena. Gerstner, whose affliction &#109;&#097;&#100;&#101; him &#115;&#111; ill &#104;&#101; &#119;&#097;&#115; unable to work over a two-year period, like Hilfiger, underwent many misdiagnoses and unnecessary surgeries in &#097;&#110; attempt to regain &#104;&#105;&#115; heath. </p>
<p>He &#119;&#105;&#108;&#108; receive the Lauren Brooks Hope Award, named &#102;&#111;&#114; Lauren Brooks, a former board member &#102;&#111;&#114; Time &#102;&#111;&#114; Lyme who gave unconditional support and education to throngs of families looking &#102;&#111;&#114; guidance in face of the disease. Brooks lost her life in 2007, and her passion and tireless effort &#119;&#105;&#108;&#108; live on in this special award in her name honoring those who &#097;&#114;&#101; making strides in research, treatment and, ultimately, a cure. </p>
<p>Past recipients of the award include Nobel Laureate Dr. Luc Montagnier and world-renown pediatrician Dr. Charles Ray Jones.</p>
<p>Thanks to Gerstner’s initial grant and subsequent grants &#102;&#114;&#111;&#109; Time &#102;&#111;&#114; Lyme, Dr. M. Karen Newell &#119;&#105;&#108;&#108; receive the Lauren Brooks Hope Award &#097;&#116; the event. Dr. Newell is conducting &#103;&#114;&#111;&#117;&#110;&#100;&#098;&#114;&#101;&#097;&#107;&#105;&#110;&#103; research in unraveling the complexities &#098;&#101;&#104;&#105;&#110;&#100; chronic Lyme disease and is contributing to making great progress toward treatment and a cure.</p>
<p>Newell’s commitment to researching and developing a protocol to treat Lyme and &#111;&#116;&#104;&#101;&#114; tick-borne diseases includes a discovery that certain immune characteristics may contribute to whether a person is susceptible &#111;&#114; resistant to the development of chronic inflammation &#097;&#115; a result of infection .</p>
<p>“The idea &#098;&#101;&#104;&#105;&#110;&#100; &#111;&#117;&#114; research is that those &#119;&#105;&#116;&#104; a genetic blueprint that &#100;&#111;&#101;&#115; not &#097;&#108;&#108;&#111;&#119; certain self-peptides to &#098;&#101; processed &#111;&#114; removed tend to mount &#097;&#110; auto-reactive &#111;&#114; chronic inflammatory immune response,” Newell says. Her theory proposes a “targeted” peptide to replace &#111;&#114; remove the self-peptides and restore a healthy immune response in patients. The study aims to shed light on the chronic inflammatory response and symptoms shared by a significant subset of Lyme disease patients.</p>
<p>“It is &#111;&#117;&#114; hope that the work of Dick Gerstner and Karen Newell &#119;&#105;&#108;&#108; reinforce the importance of proper diagnosis and lead to improved testing and prognosis &#102;&#111;&#114; Lyme and &#111;&#116;&#104;&#101;&#114; tick-borne diseases,” &#115;&#097;&#105;&#100; Diane Blanchard, co-founder &#119;&#105;&#116;&#104; Siciliano of Time &#102;&#111;&#114; Lyme. “We’ve selected &#116;&#104;&#101;&#115;&#101; honorees because we &#098;&#101;&#108;&#105;&#101;&#118;&#101; &#116;&#104;&#101;&#121; &#119;&#105;&#108;&#108; encourage others to join in and continue a steadfast battle &#097;&#103;&#097;&#105;&#110;&#115;&#116; Lyme, &#100;&#101;&#115;&#112;&#105;&#116;&#101; &#115;&#111; many children and adults having &#116;&#104;&#101;&#105;&#114; hopes dashed by ineffective testing and widespread lack of accessibility to treatment.”</p>
<p>The Gala &#119;&#105;&#108;&#108; &#098;&#101; chaired by Scott Mitchell of the high-end fashion retail store Richards of Greenwich and &#119;&#105;&#108;&#108; feature world-renowned mentalist and illusionist Shimshi, entertainment and a live and silent auction.</p>
<p>Proceeds &#102;&#114;&#111;&#109; the event &#119;&#105;&#108;&#108; &#098;&#101; used to fund &#105;&#109;&#112;&#111;&#114;&#116;&#097;&#110;&#116; research projects, medical symposiums and education. &#115;&#105;&#110;&#099;&#101; the commencement of Time &#102;&#111;&#114; Lyme’s fundraising efforts in 2001, it &#104;&#097;&#115; raised nearly $5 million and partnered &#119;&#105;&#116;&#104; Columbia University Medical Center to create its Lyme and Tick-Borne Disease Research Center. The Columbia Center is led by the efforts of Dr. Brian Fallon and &#104;&#097;&#115; &#109;&#097;&#100;&#101; significant progress in demonstrating the impact of Lyme disease on the brain and in identifying biomarkers in order to lead to improved diagnostic test and, importantly, more effective treatment.</p>
<p>In addition to funding research, Time &#102;&#111;&#114; Lyme raises money to combat and prevent &#111;&#116;&#104;&#101;&#114; tick-borne diseases &#116;&#104;&#114;&#111;&#117;&#103;&#104; education, outreach, public policy initiatives, information-sharing and support.</p>
<p>Illusions of Lyme &#119;&#105;&#108;&#108; &#098;&#101; held &#097;&#116; 6 p.m. on Saturday, April 2 &#097;&#116; the Hilton Stamford Hotel. &#102;&#111;&#114; tickets &#111;&#114; more information, &#099;&#097;&#108;&#108; 646-502-9374 &#111;&#114; visit timeforlyme.org.</p>
<p>For the original version on PRWeb visit: prweb.com/releases/prweb2011/03/prweb5123314.htm
<p>More News in this Category</p></p>
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		<title>ADHD: Always on the Go</title>
		<link>http://symptomadvice.com/adhd-always-on-the-go/</link>
		<comments>http://symptomadvice.com/adhd-always-on-the-go/#comments</comments>
		<pubDate>Tue, 11 Jan 2011 07:00:15 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[adhd symptoms]]></category>
		<category><![CDATA[columbia university]]></category>
		<category><![CDATA[tendencies]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/adhd-always-on-the-go/</guid>
		<description><![CDATA[Untreated symptoms &#099;&#097;&#110; &#111;&#102;&#116;&#101;&#110; bring &#111;&#110; feelings &#111;&#102; low self-esteem or low mood. &#116;&#104;&#101; ADHD adult &#099;&#097;&#110; &#098;&#101; a high achiever, for &#101;&#120;&#097;&#109;&#112;&#108;&#101;, but her disorganization holds her back from unmet goals &#116;&#104;&#097;&#116; &#116;&#104;&#101;&#110; lead &#116;&#111; poor self-image. &#111;&#102; &#099;&#111;&#117;&#114;&#115;&#101;, symptoms &#109;&#097;&#121; lead her straight &#116;&#111; a bout &#119;&#105;&#116;&#104; depression or &#101;&#118;&#101;&#110; chronic anxiety. What&#8217;s [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/01/1294729215-95.jpg" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" />
<p>Untreated symptoms &#099;&#097;&#110; &#111;&#102;&#116;&#101;&#110; bring &#111;&#110; feelings &#111;&#102; low self-esteem or low mood. &#116;&#104;&#101; ADHD adult &#099;&#097;&#110; &#098;&#101; a high achiever, for &#101;&#120;&#097;&#109;&#112;&#108;&#101;, but her disorganization holds her back from unmet goals &#116;&#104;&#097;&#116; &#116;&#104;&#101;&#110; lead &#116;&#111; poor self-image. &#111;&#102; &#099;&#111;&#117;&#114;&#115;&#101;, symptoms &#109;&#097;&#121; lead her straight &#116;&#111; a bout &#119;&#105;&#116;&#104; depression or &#101;&#118;&#101;&#110; chronic anxiety.</p>
<p>What&#8217;s &#109;&#111;&#114;&#101;, &#116;&#104;&#101;&#115;&#101; individuals &#097;&#114;&#101; &#097;&#108;&#115;&#111; &#109;&#111;&#114;&#101; likely &#116;&#111; smoke; smoking is twice as common &#097;&#109;&#111;&#110;&#103; people &#105;&#110; this population. Researchers at Columbia University &#097;&#114;&#101; studying smokers who have ADHD symptoms; &#116;&#104;&#101;&#121; &#097;&#114;&#101; interested &#105;&#110; &#116;&#104;&#101; effects &#111;&#102; &#116;&#104;&#101; drug methylphenidate &#097;&#110;&#100; whether it might reduce symptoms &#111;&#102; ADHD as well as tobacco withdrawal. Research like this &#109;&#097;&#121; &#104;&#101;&#108;&#112; &#117;&#115; better understand &#116;&#104;&#101; disorder.</p>
<p>Yet &#116;&#104;&#101; tendencies &#111;&#102; &#116;&#104;&#101; ADHD adult &#099;&#097;&#110; &#097;&#108;&#115;&#111; &#098;&#101; directed &#116;&#111; one&#8217;s advantage. Some, for instance, &#097;&#114;&#101; hyper-focused &#111;&#110; tasks &#116;&#104;&#097;&#116; &#105;&#110;&#116;&#101;&#114;&#101;&#115;&#116; them. That&#8217;s &#119;&#104;&#121; professions such as medicine, science, or art &#109;&#097;&#121; &#098;&#101; better suited for &#116;&#104;&#101;&#115;&#101; individuals. It&#8217;s &#110;&#111; surprise, &#116;&#104;&#101;&#110;, &#116;&#104;&#097;&#116; people like Albert Einstein, John Lennon, &#097;&#110;&#100; Beethoven &#097;&#114;&#101; said &#116;&#111; have had symptoms &#111;&#102; ADHD.</p>
<p>Sometimes, just being aware &#111;&#102; &#116;&#104;&#101; symptoms &#099;&#097;&#110; &#098;&#101; a big &#104;&#101;&#108;&#112;. &#119;&#104;&#097;&#116; you &#109;&#097;&#121; not know is &#116;&#104;&#097;&#116; &#116;&#104;&#101;&#114;&#101; &#097;&#114;&#101; &#116;&#104;&#114;&#101;&#101; types &#111;&#102; ADHD: inattentive, hyperactive, or impulsive. &#119;&#104;&#105;&#108;&#101; all types affect executive function, each &#111;&#110;&#101; has its own quirks. Here &#097;&#114;&#101; some signs &#116;&#111; look for:</p>
<p>The inattentive ADHD adult is pretty &#109;&#117;&#099;&#104; a disorganized person. She &#111;&#102;&#116;&#101;&#110; gets bored &#097;&#110;&#100; easily distracted, losing herself &#105;&#110; daydreams. &#119;&#105;&#116;&#104; little attention &#116;&#111; &#100;&#101;&#116;&#097;&#105;&#108;, she &#099;&#097;&#110; &#109;&#097;&#107;&#101; careless mistakes. All &#111;&#102; &#119;&#104;&#105;&#099;&#104; leads &#116;&#111; an inability &#116;&#111; focus &#097;&#110;&#100; follow instructions. Conversely, this person &#099;&#097;&#110; focus &#116;&#111;&#111; &#109;&#117;&#099;&#104; &#111;&#110; tasks &#111;&#102; &#105;&#110;&#116;&#101;&#114;&#101;&#115;&#116; &#097;&#110;&#100; &#099;&#097;&#110; &#101;&#118;&#101;&#110; underestimate &#116;&#104;&#101; time needed &#116;&#111; complete &#116;&#104;&#101;&#115;&#101; tasks. This &#099;&#097;&#110; fuel procrastination &#097;&#110;&#100; lateness. Don&#8217;t &#098;&#101; &#116;&#111;&#111; put off as &#116;&#104;&#101; inattentive ADHD adult &#099;&#097;&#110; appear aloof or &#101;&#118;&#101;&#110; arrogant.</p>
<p>The hyperactive suffers restlessness, &#101;&#118;&#101;&#110; fidgety hands &#097;&#110;&#100; feet. It&#8217;s not surprising &#116;&#111; &#102;&#105;&#110;&#100; this person squirming &#105;&#110; general. He &#097;&#108;&#115;&#111; is known &#116;&#111; talk excessively, hopping from &#111;&#110;&#101; topic &#116;&#111; another. She &#109;&#097;&#121; &#098;&#101; dogged &#098;&#121; feelings &#111;&#102; being overwhelmed.</p>
<p>The impulsive type &#109;&#097;&#121; suffer irritability, anger, &#097;&#110;&#100; impatience. She, &#105;&#110; fact, &#099;&#097;&#110;&#110;&#111;&#116; curb her reactions. &#105;&#110; interactions &#119;&#105;&#116;&#104; &#111;&#116;&#104;&#101;&#114;&#115;, he &#109;&#097;&#121; speak &#119;&#105;&#116;&#104;&#111;&#117;&#116; thinking, interrupt &#111;&#116;&#104;&#101;&#114;&#115;, &#097;&#110;&#100; suffer poor timing. &#116;&#104;&#101;&#115;&#101; people &#115;&#111;&#109;&#101;&#116;&#105;&#109;&#101;&#115; suffer addictions like impulsive shopping or &#101;&#118;&#101;&#110; eating disorders.</p>
<p>Many people who have ADHD see &#109;&#097;&#114;&#107;&#101;&#100; improvement through a combination &#111;&#102; talk therapy &#097;&#110;&#100; medication. But each person is &#100;&#105;&#102;&#102;&#101;&#114;&#101;&#110;&#116;, so treatment plans must &#098;&#101; tailored &#116;&#111; &#116;&#104;&#101; individual. Here &#097;&#114;&#101; some steps you &#099;&#097;&#110; take &#116;&#111; combat ADHD. &#102;&#105;&#114;&#115;&#116;, consult a mental health professional &#097;&#110;&#100; ask for a &#116;&#104;&#111;&#114;&#111;&#117;&#103;&#104; assessment covering &#101;&#118;&#101;&#114;&#121;&#116;&#104;&#105;&#110;&#103; from attention span &#116;&#111; medical exam. &#097;&#108;&#115;&#111; ask about medications such as Ritalin &#097;&#110;&#100; Adderall. &#100;&#105;&#102;&#102;&#101;&#114;&#101;&#110;&#116; drugs, &#104;&#111;&#119;&#101;&#118;&#101;&#114;, work for &#100;&#105;&#102;&#102;&#101;&#114;&#101;&#110;&#116; individuals; you &#109;&#097;&#121; have &#116;&#111; &#116;&#114;&#121; &#111;&#110;&#101; &#097;&#110;&#100; &#116;&#104;&#101;&#110; another. &#112;&#108;&#117;&#115;, studying up &#111;&#110; ADHD &#119;&#105;&#108;&#108; &#104;&#101;&#108;&#112; as well as building skills like using to-do lists, day planners, &#097;&#110;&#100; filing systems. You &#099;&#097;&#110; &#097;&#108;&#115;&#111; divide large tasks into smaller &#109;&#111;&#114;&#101; manageable &#111;&#110;&#101;&#115;, &#116;&#104;&#097;&#116; way you &#119;&#105;&#108;&#108; not feel so overwhelmed. &#105;&#102; you need &#102;&#117;&#114;&#116;&#104;&#101;&#114; tools &#116;&#111; manage &#121;&#111;&#117;&#114; behavior, &#116;&#114;&#121; meditation or relaxation techniques. &#097;&#110;&#100; lastly, turning &#116;&#111; &#111;&#116;&#104;&#101;&#114;&#115; &#098;&#121; joining an ADHD support group &#119;&#105;&#108;&#108; let you know you &#097;&#114;&#101; not &#097;&#108;&#111;&#110;&#101;.</p></p>
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		<title>The Most Promising New Schizophrenia Drug In Years?</title>
		<link>http://symptomadvice.com/the-most-promising-new-schizophrenia-drug-in-years/</link>
		<comments>http://symptomadvice.com/the-most-promising-new-schizophrenia-drug-in-years/#comments</comments>
		<pubDate>Mon, 20 Dec 2010 04:51:08 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[schizophrenia symptoms]]></category>
		<category><![CDATA[columbia university]]></category>
		<category><![CDATA[eli lilly]]></category>
		<category><![CDATA[geodon]]></category>
		<category><![CDATA[jeffrey lieberman]]></category>
		<category><![CDATA[pfizer]]></category>
		<category><![CDATA[zyprexa]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/the-most-promising-new-schizophrenia-drug-in-years/</guid>
		<description><![CDATA[A new Roche drug that treats &#116;&#104;&#101; listlessness &#097;&#110;&#100; apathy experienced &#098;&#121; schizophrenics &#105;&#115; “the most exciting development &#105;&#110; &#116;&#104;&#101; therapeutics of schizophrenia &#105;&#110; &#097; long time,” &#097;&#099;&#099;&#111;&#114;&#100;&#105;&#110;&#103; to &#097; &#116;&#111;&#112; psychiatry researcher. The researcher, Columbia University’s Jeffrey Lieberman, &#105;&#115; excited because &#116;&#104;&#101; new medicine, RG1678, works entirely differently &#102;&#114;&#111;&#109; &#116;&#104;&#101; drugs that preceded &#105;&#116;, [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2010/12/1292820669-80.jpg" style="clear:both;clear:both;margin:0 15px 15px 0" />
<p>A new Roche drug that treats &#116;&#104;&#101; listlessness &#097;&#110;&#100; apathy experienced &#098;&#121; schizophrenics &#105;&#115; “the most exciting development &#105;&#110; &#116;&#104;&#101; therapeutics of schizophrenia &#105;&#110; &#097; long time,” &#097;&#099;&#099;&#111;&#114;&#100;&#105;&#110;&#103; to &#097; &#116;&#111;&#112; psychiatry researcher.</p>
<p>The researcher, Columbia University’s Jeffrey Lieberman, &#105;&#115; excited because &#116;&#104;&#101; new medicine, RG1678, works entirely differently &#102;&#114;&#111;&#109; &#116;&#104;&#101; drugs that preceded &#105;&#116;, &#119;&#097;&#115; designed rationally, &#097;&#110;&#100; treats symptoms of &#116;&#104;&#101; disease that current entrants don&#8217;t address.</p>
<p>Lieberman played &#097; pivotal role &#105;&#110; testing current &#098;&#105;&#103; selling schizophrenia drugs &#115;&#117;&#099;&#104; as Eli Lilly’s Zyprexa, Pfizer’s Geodon &#097;&#110;&#100; Bristol-Myers Squibb &#097;&#110;&#100; Otsuka’s Abilify. But he also ran &#097; large clinical trial, run &#098;&#121; &#116;&#104;&#101; National Institutes of Health, that &#104;&#097;&#115; been widely interpreted as meaning that advantages of &#116;&#104;&#101;&#115;&#101; drugs, known as second-generation antipsychotics, &#097;&#114;&#101; &#109;&#111;&#114;&#101; limited than doctors originally &#116;&#104;&#111;&#117;&#103;&#104;&#116;.</p>
<p>RG1687 &#105;&#115; &#097; glycine reuptake inhibitor. &#105;&#116; inhibits &#116;&#104;&#101; re-absorption of glycine, &#097; important neurotransmitter, &#116;&#104;&#101;&#114;&#101;&#098;&#121; normalizing levels of glutamate, another brain chemical &#116;&#104;&#111;&#117;&#103;&#104;&#116; to be important &#105;&#110; schizophrenia. Experts have been discussing boosting glycine for &#109;&#111;&#114;&#101; than &#097; decade. Lieberman emphasizes that &#116;&#104;&#101;&#115;&#101; drugs were developed “rationally, as opposed to serendipitously.”</p>
<p>However, Lieberman cautions, longer studies &#097;&#114;&#101; &#103;&#111;&#105;&#110;&#103; to be critical &#105;&#110; proving if &#116;&#104;&#105;&#115; drug works. Roche, which released &#116;&#104;&#101; results &#105;&#110; &#097; press release, says that &#098;&#105;&#103;&#103;&#101;&#114; clinical trials &#097;&#114;&#101; being conducted &#119;&#105;&#116;&#104; &#116;&#104;&#101; hope of filing for regulatory approval.</p>
<p>Roche’s medicine &#105;&#115; important &#110;&#111;&#116; just because &#105;&#116; works &#105;&#110; &#097; new &#119;&#097;&#121;, but also because &#105;&#116; treats symptoms of schizophrenia that other medicines don’t. Most drugs &#097;&#114;&#101; targeted &#097;&#103;&#097;&#105;&#110;&#115;&#116; &#116;&#104;&#101; so-called positive symptoms of schizophrenia, &#116;&#104;&#101; obvious, acute problems &#108;&#105;&#107;&#101; hallucinations. RG1678 &#105;&#115; being tested as &#097; treatment for &#116;&#104;&#101; negative symptoms of &#116;&#104;&#101; disease, which include apathy &#097;&#110;&#100; poor or nonexistent social functioning. &#116;&#104;&#101;&#115;&#101; problems can be debilitating for schizophrenic patients, &#119;&#104;&#111; experience &#116;&#104;&#101;&#109; &#118;&#101;&#114;&#121; frequently. Roche hopes that &#116;&#104;&#101; first &#117;&#115;&#101; of RG1678 &#119;&#105;&#108;&#108; be &#105;&#110; patients &#119;&#104;&#111; &#097;&#114;&#101; on other schizophrenia drugs, but &#119;&#104;&#111; &#110;&#101;&#101;&#100; relief &#102;&#114;&#111;&#109; &#116;&#104;&#101; negative symptoms of &#116;&#104;&#101; disease.</p>
<p>Although Roche &#115;&#097;&#105;&#100; that patients &#119;&#104;&#111; &#100;&#105;&#100; &#110;&#111;&#116; withdraw &#102;&#114;&#111;&#109; &#116;&#104;&#101; study had &#097; significant reduction &#105;&#110; negative symptoms, &#116;&#104;&#101; drug &#100;&#105;&#100; have &#115;&#105;&#100;&#101; effects. There &#119;&#097;&#115; &#097; panic attack, &#097; suicide attempt, &#097;&#110;&#100; &#097; case of anxiety &#105;&#110; &#116;&#104;&#101; drug group, &#097;&#110;&#100; there &#119;&#097;&#115; &#097; dose-dependent decrease &#105;&#110; hemoglobin that &#119;&#097;&#115; &#110;&#111;&#116; considered clinically significant.</p></p>
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