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	<title>Symptom Advice .com &#187; emotional function</title>
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		<title>Brain scans detect autism in preliminary study at McLean</title>
		<link>http://symptomadvice.com/brain-scans-detect-autism-in-preliminary-study-at-mclean/</link>
		<comments>http://symptomadvice.com/brain-scans-detect-autism-in-preliminary-study-at-mclean/#comments</comments>
		<pubDate>Mon, 20 Dec 2010 10:00:08 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[autism symptoms]]></category>
		<category><![CDATA[3 years]]></category>
		<category><![CDATA[autism research]]></category>
		<category><![CDATA[emotional function]]></category>
		<category><![CDATA[mclean hospital]]></category>
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		<description><![CDATA[Scans that reveal flaws in the brain&#8217;s circuitry &#109;&#097;&#121; &#111;&#110;&#101; day be &#117;&#115;&#101;&#100; &#116;&#111; diagnose autism, researchers &#102;&#114;&#111;&#109; McLean Hospital &#115;&#097;&#121; in a report published last week. Nicholas Lange and colleagues write in the journal Autism Research that &#116;&#104;&#101;&#105;&#114; neuroimaging studies &#119;&#101;&#114;&#101; able &#116;&#111; distinguish people with autism &#102;&#114;&#111;&#109; control subjects 94 percent of the [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2010/12/1292839208-92.png" style="float:left;clear:both;margin:0 15px 15px 0" />
<p>Scans that reveal flaws in the brain&#8217;s circuitry &#109;&#097;&#121; &#111;&#110;&#101; day be &#117;&#115;&#101;&#100; &#116;&#111; diagnose autism, researchers &#102;&#114;&#111;&#109; McLean Hospital &#115;&#097;&#121; in a report published last week.</p>
<p>Nicholas Lange and colleagues write in the journal Autism Research that &#116;&#104;&#101;&#105;&#114; neuroimaging studies &#119;&#101;&#114;&#101; able &#116;&#111; distinguish people with autism &#102;&#114;&#111;&#109; control subjects 94 percent of the time using an MRI that took about 10 minutes. The scans focused on three parts of the brain that are &#107;&#110;&#111;&#119;&#110; &#116;&#111; be impaired in autism: areas involving language, social and emotional function. &#099;&#117;&#114;&#114;&#101;&#110;&#116;&#108;&#121; autism &#105;&#115; diagnosed &#097;&#102;&#116;&#101;&#114; hours of interviews with parents and observation of a child, &#117;&#115;&#117;&#097;&#108;&#108;&#121; 2 &#116;&#111; 3 years old, &#119;&#104;&#111; does not &#097;&#112;&#112;&#101;&#097;&#114; &#116;&#111; be developing &#110;&#111;&#114;&#109;&#097;&#108;&#108;&#121;.</p>
<p>&#8220;&#119;&#101; &#097;&#108;&#108; &#119;&#097;&#110;&#116; &#116;&#111; know what &#119;&#101; can and cannot change about the disorder and how &#116;&#111; improve the lives of people with autism,&#8217;&#8217; Lange said in an interview. &#8220;&#116;&#104;&#105;&#115; &#105;&#115; a major step &#116;&#111;&#119;&#097;&#114;&#100; that goal and more research &#110;&#101;&#101;&#100;&#115; &#116;&#111; be done &#098;&#101;&#102;&#111;&#114;&#101; &#105;&#116; &#105;&#115; ready &#102;&#111;&#114; clinical use.&#8217;&#8217;</p>
<p>For the study, the researchers examined the brains of 30 people &#102;&#114;&#111;&#109; 7 &#116;&#111; 28 years old with high-functioning autism and compared them &#116;&#111; the brains of 30 similar people with normal development. The MRIs &#115;&#104;&#111;&#119;&#101;&#100; differences &#098;&#101;&#116;&#119;&#101;&#101;&#110; the two groups in how &#116;&#105;&#110;&#121; fibers &#098;&#101;&#116;&#119;&#101;&#101;&#110; nerve cells &#119;&#101;&#114;&#101; organized.</p>
<p>Out of the 30 people with autism, 28 &#119;&#101;&#114;&#101; correctly identified based on scans that suggested information could not flow &#097;&#115; easily through faulty neural connections. Out of the 30 controls &#119;&#105;&#116;&#104;&#111;&#117;&#116; autism, three &#119;&#101;&#114;&#101; incorrectly labeled.</p>
<p>In an interview, Lange &#109;&#097;&#100;&#101; an analogy &#116;&#111; the electrical wiring &#098;&#101;&#116;&#119;&#101;&#101;&#110; a lamp and a wall socket. If the insulation on the wire &#105;&#115; faulty, electricity cannot flow properly. In the &#115;&#097;&#109;&#101; way, if the fibers &#098;&#101;&#116;&#119;&#101;&#101;&#110; nerve cells in the brain are not well insulated with myelin, or if the fibers are disorganized, signals cannot travel &#097;&#115; well.</p>
<p>They did not see differences &#098;&#101;&#116;&#119;&#101;&#101;&#110; the brains of older and younger people with autism, hinting that problems in brain development &#109;&#097;&#121; occur &#098;&#101;&#102;&#111;&#114;&#101; age 7. Lange said further research will &#108;&#111;&#111;&#107; &#097;&#116; younger people and &#097;&#116; people with more severe forms of the disorder.</p>
<p>An autism specialist not involved in the study &#097;&#108;&#115;&#111; said more research &#105;&#115; needed &#098;&#101;&#102;&#111;&#114;&#101; the technique can be considered &#102;&#111;&#114; use &#097;&#115; a diagnostic tool. Dr. Stewart H. Mostofsky, director of the Laboratory &#102;&#111;&#114; Neurocognitive and Imaging Research and medical director of the Center &#102;&#111;&#114; Autism and Related Disorders &#097;&#116; the Kennedy Krieger Institute in Baltimore, noted that the &#098;&#105;&#103;&#103;&#101;&#115;&#116; differences in the brain scans &#115;&#104;&#111;&#119;&#101;&#100; &#117;&#112; in areas central &#116;&#111; language.</p>
<p>&#8220;The critical issue &#105;&#115; not distinguishing children with autism &#102;&#114;&#111;&#109; typically developing children but distinguishing children with autism &#102;&#114;&#111;&#109; children with developmental language disorders or language impairment,&#8217;&#8217; &#104;&#101; said. &#8220;&#105;&#116; &#105;&#115; &#099;&#101;&#114;&#116;&#097;&#105;&#110;&#108;&#121; &#112;&#111;&#115;&#115;&#105;&#098;&#108;&#101; that the primary [difference] &#105;&#115; not necessarily autism presenting but rather the language impairments that are &#097;&#115;&#115;&#111;&#099;&#105;&#097;&#116;&#101;&#100; with autism.&#8217;&#8217; ELIZABETH COONEY </p></p>
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