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	<title>Symptom Advice .com &#187; gap</title>
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		<title>Tmj problem. pretty serious, please read/help? :(?</title>
		<link>http://symptomadvice.com/tmj-problem-pretty-serious-please-readhelp/</link>
		<comments>http://symptomadvice.com/tmj-problem-pretty-serious-please-readhelp/#comments</comments>
		<pubDate>Mon, 25 Jul 2011 10:34:17 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[lockjaw symptoms]]></category>
		<category><![CDATA[2cm]]></category>
		<category><![CDATA[5 months]]></category>
		<category><![CDATA[braces]]></category>
		<category><![CDATA[gap]]></category>
		<category><![CDATA[peers]]></category>
		<category><![CDATA[upper teeth]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/tmj-problem-pretty-serious-please-readhelp/</guid>
		<description><![CDATA[hello, i &#097;&#109; a girl &#105;&#110; hs &#097;&#110;&#100; &#102;&#111;&#114; &#097;&#098;&#111;&#117;&#116; 2-3 years &#110;&#111;&#119;, i have &#104;&#097;&#100; symptoms associated with tmj. my mouth doesn&#039;t open fully, &#105;&#116; &#111;&#110;&#108;&#121; opens &#097;&#098;&#111;&#117;&#116; 3-4 inches. my jaws &#119;&#111;&#117;&#108;&#100; hurt &#105;&#102; i chew a lot of hard/taffy &#108;&#105;&#107;&#101; stuff. &#097;&#110;&#100; sometimes i get lockjaws typically &#105;&#110; &#116;&#104;&#101; morning. recently though, [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/07/1311590057-73.gif" style="clear:both;clear:both;margin:0 15px 15px 0" />
<p>hello, i &#097;&#109; a girl &#105;&#110; hs &#097;&#110;&#100; &#102;&#111;&#114; &#097;&#098;&#111;&#117;&#116; 2-3 years &#110;&#111;&#119;, i have &#104;&#097;&#100; symptoms associated with tmj. my mouth doesn&#039;t open fully, &#105;&#116; &#111;&#110;&#108;&#121; opens &#097;&#098;&#111;&#117;&#116; 3-4 inches. my jaws &#119;&#111;&#117;&#108;&#100; hurt &#105;&#102; i chew a lot of hard/taffy &#108;&#105;&#107;&#101; stuff. &#097;&#110;&#100; sometimes i get lockjaws typically &#105;&#110; &#116;&#104;&#101; morning. <br /> recently though, (about 6months ago) i&#039;ve noticed my upper jaw &#104;&#097;&#115; &#098;&#101;&#101;&#110; shifting to &#116;&#104;&#101; front, &#110;&#111;&#116; allowing my upper teeth to meet my bottom. &#105;&#116; &#105;&#115; shifting everyday, &#110;&#111;&#119; my upper set of teeth or jaw wont meet with my bottom set of teeth. &#105;&#116; &#104;&#097;&#115; a &#098;&#105;&#103; big gap &#119;&#104;&#105;&#099;&#104; &#105;&#102; i close my mouth, i can squeeze out my tongue &#116;&#104;&#114;&#111;&#117;&#103;&#104; &#116;&#104;&#101; gap &#097;&#098;&#111;&#117;&#116; 1cm-2cm or so. (so gross/scary) this &#104;&#097;&#115; caused me to develope a nasty lisp, &#119;&#104;&#105;&#099;&#104; i didnt realize at &#102;&#105;&#114;&#115;&#116;, my peers told me &#097;&#098;&#111;&#117;&#116; &#105;&#116;. <br /> I NEVER &#104;&#097;&#100; a lisp &#097;&#110;&#100; my upper set or teeth &#097;&#110;&#100; bottom set ALWAYS matched. i dont &#107;&#110;&#111;&#119; whats happeneing, &#119;&#104;&#097;&#116; can i &#100;&#111; &#105;&#110; this situation? &#097;&#110;&#100; my jaw &#105;&#115; moving around everyday, relocating &#105;&#116; &#115;&#101;&#108;&#102; &#111;&#110; my face! my face shape even changed a bit!<br /> ive talked to my dentist &#097;&#098;&#111;&#117;&#116; &#105;&#116;, but they assigned me to a specialist &#097;&#110;&#100; i wont &#115;&#101;&#101; him &#102;&#111;&#114; another 4-5 months. <br /> and &#119;&#111;&#117;&#108;&#100; they &#103;&#105;&#118;&#101; me braces? or surgery? &#098;&#101;&#099;&#097;&#117;&#115;&#101; &#105;&#116;&#115; pretty serious tmj. AHHH</p>
<p> please, &#104;&#101;&#108;&#112; me out i &#097;&#109; so scared. <br /> thanks alot</p>
<p>in case &#121;&#111;&#117; haven&#039;t &#098;&#101;&#101;&#110; told TMJ &#105;&#115; a form of arthritis. &#105;&#116; can affect any &#112;&#097;&#114;&#116; of your body. &#105;&#116; &#105;&#115; &#107;&#110;&#111;&#119;&#110; &#097;&#115; &#116;&#104;&#101; &#103;&#114;&#101;&#097;&#116; deceiver. &#119;&#104;&#105;&#108;&#101; &#121;&#111;&#117; wait &#102;&#111;&#114; &#116;&#104;&#101; specialist go to walmart, &#105;&#110; &#116;&#104;&#101; pharmacy dept &#097;&#110;&#100; get &#116;&#104;&#101; apparatus &#116;&#104;&#097;&#116; will &#104;&#101;&#108;&#112; &#121;&#111;&#117; to quit grinding your teeth at night. Stay &#097;&#119;&#097;&#121; &#102;&#114;&#111;&#109; hard foods. &#105;&#116; may &#104;&#101;&#108;&#112; to put heat &#111;&#110; &#116;&#104;&#101; side of your jaw (helps mine) &#116;&#114;&#121; to avoid stress. Look up TMJ &#111;&#110; &#116;&#104;&#101; internet to learn &#109;&#111;&#114;&#101; &#097;&#098;&#111;&#117;&#116; &#105;&#116;. TMJ stands &#102;&#111;&#114; Temporal Mandibular Joint. &#097;&#110;&#100; &#105;&#116; &#105;&#115; a pain.<br />Don&#039;t &#098;&#101; afraid. Evey thing will &#098;&#101; &#111;&#107;.</p></p>
]]></content:encoded>
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		<title>Sciatic Nerve Pain: Symptoms and Treatments</title>
		<link>http://symptomadvice.com/sciatic-nerve-pain-symptoms-and-treatments/</link>
		<comments>http://symptomadvice.com/sciatic-nerve-pain-symptoms-and-treatments/#comments</comments>
		<pubDate>Wed, 20 Apr 2011 19:00:18 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[pain symptoms]]></category>
		<category><![CDATA[gap]]></category>
		<category><![CDATA[nerve pain]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/sciatic-nerve-pain-symptoms-and-treatments/</guid>
		<description><![CDATA[It &#105;&#115; crucial to know the reasons why sciatic nerve pain happens in order &#102;&#111;&#114; you to know &#116;&#104;&#101;&#105;&#114; proper treatments. The Sciatic nerve &#105;&#115; &#107;&#110;&#111;&#119;&#110; to &#098;&#101; the longest nerve of the body. &#119;&#104;&#101;&#110; &#116;&#104;&#105;&#115; nerve &#103;&#101;&#116;&#115; swollen or &#103;&#101;&#116;&#115; squeezed, a symptom called the Sciatica occurs. The pinched nerve &#105;&#115; called the compressed [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/04/1303326038-23.gif" style="float:left;clear:both;margin:0 15px 15px 0" />
<p>It &#105;&#115; crucial to know the reasons why sciatic nerve pain happens in order &#102;&#111;&#114; you to know &#116;&#104;&#101;&#105;&#114; proper treatments. The Sciatic nerve &#105;&#115; &#107;&#110;&#111;&#119;&#110; to &#098;&#101; the longest nerve of the body. &#119;&#104;&#101;&#110; &#116;&#104;&#105;&#115; nerve &#103;&#101;&#116;&#115; swollen or &#103;&#101;&#116;&#115; squeezed, a symptom called the Sciatica occurs. The pinched nerve &#105;&#115; called the compressed nerve.</p>
<p>Sciatic nerve pain &#105;&#115; caused by a lot of reasons. Some of the more popular &#097;&#110;&#100; well &#107;&#110;&#111;&#119;&#110; ones include a disc belonging to the Lumbar Spine that &#103;&#101;&#116;&#115; herniated. &#116;&#104;&#105;&#115; happens &#119;&#104;&#101;&#110; the spinal disc center &#105;&#115; compressed &#097;&#103;&#097;&#105;&#110;&#115;&#116; the nerve roots of the spinal cord. Spinal Stenosis &#105;&#115; &#097;&#108;&#115;&#111; a well &#107;&#110;&#111;&#119;&#110; cause. &#116;&#104;&#105;&#115; &#105;&#115; &#119;&#104;&#101;&#110; the nerve roots are pressured &#097;&#103;&#097;&#105;&#110;&#115;&#116; the spinal cord &#098;&#101;&#099;&#097;&#117;&#115;&#101; the gap of the spinal canal &#103;&#101;&#116;&#115; narrowed. On the &#111;&#116;&#104;&#101;&#114; hand, Spinal Osteoarthritis occurs whenever the nerve &#105;&#115; irritated by some factors like the bone, piriformis syndrome, &#097;&#110;&#100; a few more. &#097;&#110;&#111;&#116;&#104;&#101;&#114; cause of sciatic nerve pain &#105;&#115; Spondylolishtesis. &#116;&#104;&#105;&#115; &#105;&#115; &#119;&#104;&#101;&#110; the vertebrae &#098;&#101;&#099;&#111;&#109;&#101;&#115; misaligned &#097;&#110;&#100; causes an impairment of the sciatic nerve. Pregnancy, muscle strain &#097;&#110;&#100; Piriformis Syndrome are &#116;&#104;&#114;&#101;&#101; &#111;&#116;&#104;&#101;&#114; causes of sciatic nerve pain.</p>
<p>The presence of these symptoms results to a sharp pain that begins &#102;&#114;&#111;&#109; the &#108;&#111;&#119;&#101;&#114; portion of the &#098;&#097;&#099;&#107; &#097;&#110;&#100; then &#103;&#111;&#101;&#115; &#100;&#111;&#119;&#110; to the &#098;&#097;&#099;&#107; of the legs, the knee &#097;&#110;&#100; the foot. What &#105;&#115; unique &#097;&#098;&#111;&#117;&#116; &#116;&#104;&#105;&#115; kind of pain &#105;&#115; that &#105;&#116; &#105;&#115; only felt on the &#104;&#097;&#108;&#102; side of our body &#097;&#110;&#100; &#097;&#108;&#119;&#097;&#121;&#115; in the place &#119;&#104;&#101;&#114;&#101; that nerve impairment &#105;&#115; located.</p>
<p>Generally, the treatment of sciatic nerve pain &#105;&#115; through conventional methods. &#104;&#111;&#119;&#101;&#118;&#101;&#114;, not all of these treatments are effective. In order &#102;&#111;&#114; the patient to &#098;&#101; relieved of the pain, massage therapy should &#098;&#101; done numerous times &#116;&#111;&#103;&#101;&#116;&#104;&#101;&#114; with a few stretching exercises &#102;&#111;&#114; the purpose of concentrating on the spastic muscles &#097;&#110;&#100; calming &#116;&#104;&#101;&#109; as well. There are pain medications &#097;&#110;&#100; muscle relaxants that some doctors prescribe. Anti-depressants &#099;&#097;&#110; &#097;&#108;&#115;&#111; &#104;&#101;&#108;&#112; in pain management in the &#115;&#097;&#109;&#101; &#119;&#097;&#121; that steroid injections &#109;&#097;&#100;&#101; epidurally are used to lessen inflammation &#097;&#110;&#100; nerve pressure. &#119;&#104;&#105;&#108;&#101; these medications are &#118;&#101;&#114;&#121; efficient, they &#097;&#108;&#115;&#111; carry significant side effects &#116;&#104;&#117;&#115; patients are allowed a maximum of &#116;&#104;&#114;&#101;&#101; injections &#112;&#101;&#114; year.</p>
<p>The method of sciatic nerve pain treatment &#099;&#097;&#110; either &#098;&#101; natural, conventional, minimally invasive or through surgical means. &#119;&#104;&#097;&#116;&#101;&#118;&#101;&#114; &#098;&#101; the case, all they aim &#102;&#111;&#114; &#105;&#115; to relieve the patient &#102;&#114;&#111;&#109; sciatic nerve pain. &#105;&#116; all depends on how the patient prefers to &#098;&#101; treated.</p></p>
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		<title>Psoriatic Arthritis Symptoms In Children</title>
		<link>http://symptomadvice.com/psoriatic-arthritis-symptoms-in-children/</link>
		<comments>http://symptomadvice.com/psoriatic-arthritis-symptoms-in-children/#comments</comments>
		<pubDate>Sun, 10 Apr 2011 16:00:11 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[diagnose symptoms]]></category>
		<category><![CDATA[arthritis]]></category>
		<category><![CDATA[arthritis symptoms]]></category>
		<category><![CDATA[caucasian population]]></category>
		<category><![CDATA[gap]]></category>
		<category><![CDATA[red patchy skin]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/psoriatic-arthritis-symptoms-in-children/</guid>
		<description><![CDATA[Psoriatic arthritis &#105;&#115; a combination illness expressing symptoms of both psoriasis and arthritis. Psoriasis &#105;&#115; a skin condition that manifests with red, patchy skin and swelling. Arthritis &#105;&#115; characterized &#098;&#121; an inflammation of &#116;&#104;&#101; joints and pain &#105;&#110; &#116;&#104;&#101; joints. &#119;&#104;&#101;&#110; &#116;&#104;&#101; two conditions &#097;&#114;&#101; combined, about 2% of &#116;&#104;&#101; Caucasian population &#105;&#115; affected. Most [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/04/1302451213-25.jpg" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" /></p>
<p>Psoriatic arthritis &#105;&#115; a combination illness expressing symptoms of both psoriasis and arthritis. Psoriasis &#105;&#115; a skin condition that manifests with red, patchy skin and swelling. Arthritis &#105;&#115; characterized &#098;&#121; an inflammation of &#116;&#104;&#101; joints and pain &#105;&#110; &#116;&#104;&#101; joints. &#119;&#104;&#101;&#110; &#116;&#104;&#101; two conditions &#097;&#114;&#101; combined, about 2% of &#116;&#104;&#101; Caucasian population &#105;&#115; affected.</p>
<p><strong>Most Common Areas Affected</strong></p>
<p>The areas &#109;&#111;&#115;&#116; commonly affected &#098;&#121; psoriatic arthritis symptoms include &#116;&#104;&#101; knees, elbows, scalp, belly button, genitals and anus. &#119;&#104;&#105;&#108;&#101; &#111;&#110;&#108;&#121; 2% of &#116;&#104;&#101; total population may be affected, &#110;&#101;&#097;&#114;&#108;&#121; 10% of &#116;&#104;&#101; people diagnosed with psoriasis &#097;&#114;&#101; affected &#098;&#121; inflammation that &#099;&#111;&#117;&#108;&#100; be deemed arthritic. If a patient present with psoriasis and arthritis, &#116;&#104;&#101; condition &#105;&#115; automatically termed psoriatic arthritis. About one million people &#099;&#117;&#114;&#114;&#101;&#110;&#116;&#108;&#121; have &#116;&#104;&#101; condition and &#116;&#104;&#101; numbers &#097;&#114;&#101; equal &#097;&#109;&#111;&#110;&#103; men and women. &#116;&#104;&#105;&#115; &#105;&#115; &#110;&#111;&#116; a gender discerning condition.</p>
<p><strong>First Symptoms</strong></p>
<p>The first symptoms may appear &#116;&#111; be common signs of aging. &#116;&#104;&#101;&#115;&#101; may include pain appearing &#105;&#110; &#116;&#104;&#101; hands, feet and elbows. &#116;&#104;&#101; joints may appear purple &#105;&#110; color. As &#116;&#104;&#101; condition &#109;&#111;&#115;&#116; often hits &#116;&#104;&#101; aged population, &#116;&#104;&#101;&#114;&#101; &#105;&#115; often a large gap between &#116;&#104;&#101; presentation of &#116;&#104;&#101;&#115;&#101; symptoms and &#116;&#104;&#101; official diagnosis &#119;&#104;&#105;&#099;&#104; can lead &#116;&#111; additional joint problems that &#099;&#097;&#110;&#110;&#111;&#116; be reversed.</p>
<p><strong>Who &#105;&#115; &#109;&#111;&#115;&#116; Often Affected?</strong></p>
<p>While &#116;&#104;&#101; condition &#109;&#111;&#115;&#116; often presents &#105;&#110; 40 and 50 year olds, younger cases have &#098;&#101;&#101;&#110; noted. &#116;&#104;&#101; skin symptoms and arthritic symptom rarely present at &#116;&#104;&#101; &#115;&#097;&#109;&#101; time &#105;&#110; patients. &#109;&#111;&#115;&#116; often, skin &#119;&#105;&#108;&#108; &#115;&#104;&#111;&#119; &#116;&#104;&#101; signs of psoriasis and a doctor &#119;&#105;&#108;&#108; diagnose that condition. Later, &#119;&#104;&#101;&#110; arthritis appears, &#116;&#104;&#101; combination diagnosis &#105;&#115; given. &#116;&#104;&#101; time span between &#116;&#104;&#101; initial diagnosis of arthritis or psoriasis and &#116;&#104;&#101; presentation of &#116;&#104;&#101; contributing symptoms can be 20 years or more. &#116;&#104;&#101; longer &#116;&#104;&#101; time frame between initial diagnosis &#116;&#104;&#101; presentation of a second set of symptoms &ndash; &#116;&#104;&#101; harder psoriatic arthritis &#105;&#115; &#116;&#111; diagnose. </p>
<p><strong>Other Body Systems Affected</strong></p>
<p>The skin and joints &#097;&#114;&#101; &#110;&#111;&#116; &#116;&#104;&#101; &#111;&#110;&#108;&#121; body systems affected &#098;&#121; &#116;&#104;&#101; condition. As a rheumatic disease, inflammation can affect internal organs as &#119;&#101;&#108;&#108;. &#116;&#104;&#101; eyes, heart, lungs and kidneys &#097;&#114;&#101; &#109;&#111;&#115;&#116; often affected. &#119;&#104;&#101;&#110; rheumatic symptoms present, doctors may confuse &#116;&#104;&#101; psoriatic arthritis for other conditions like Crohn&#039;s disease, ulcerative colitis or reactive arthritis. &#116;&#104;&#101; difficulty with final diagnosis &#105;&#115; compounded if &#116;&#104;&#101; spine shows signs of inflammation as &#116;&#104;&#101;&#114;&#101; &#097;&#114;&#101; &#115;&#101;&#118;&#101;&#114;&#097;&#108; arthritic conditions that can cause spine swelling.</p>
<p><strong>Can Permanent &#100;&#097;&#109;&#097;&#103;&#101; Occur?</strong></p>
<p>The inflammation and swelling associated with &#116;&#104;&#101; condition can lead &#116;&#111; permanent &#100;&#097;&#109;&#097;&#103;&#101; of &#116;&#104;&#101; joints. &#105;&#110; some cases, &#116;&#104;&#101; connective and protective tissues between &#116;&#104;&#101; finger and knee joints can deteriorate &#116;&#111; &#116;&#104;&#101; point that bone &#105;&#115; rubbing on bone. If &#116;&#104;&#101; condition &#105;&#115; &#110;&#111;&#116; treated surgically, &#116;&#104;&#101; joints &#119;&#105;&#108;&#108; begin changing shape direction. &#116;&#104;&#101; pain can be unbearable &#119;&#104;&#101;&#110; psoriatic arthritis reaches &#116;&#104;&#105;&#115; level of severity.</p>
<p><strong>How &#116;&#111; &#103;&#101;&#116; Help</strong></p>
<p>If a patient &#105;&#115; diagnosed with psoriasis, &#116;&#104;&#101;&#114;&#101; &#105;&#115; a good chance arthritis &#119;&#105;&#108;&#108; &#099;&#111;&#109;&#101; about with age. &#116;&#104;&#101;&#115;&#101; patients &#110;&#101;&#101;&#100; &#116;&#111; watch &#111;&#117;&#116; for swelling and pain &#105;&#110; &#116;&#104;&#101; joints and report &#097;&#110;&#121; changes &#116;&#111; their skin and family physicians.</p>
<p>Having arthritis first makes diagnosis a bit easier. Psoriasis present with very noticeable symptoms and if skin changes occur, &#116;&#104;&#101; patient &#119;&#105;&#108;&#108; also have &#116;&#111; speak with their family physician about &#116;&#104;&#101; chance of having psoriatic arthritis. &#104;&#111;&#119;&#101;&#118;&#101;&#114;, a skin doctor or dermatologist &#119;&#105;&#108;&#108; &#110;&#101;&#101;&#100; &#116;&#111; be seen as &#119;&#101;&#108;&#108;.</p>
<p>A &#103;&#114;&#101;&#097;&#116; all Natural Anti-Inflammatory supplemnt &#116;&#111; add &#116;&#111; your diet &#116;&#111; combat &#116;&#104;&#101; pain of Psoriasis &#105;&#115; Nopalea.</p></p>
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		<title>Leaks in Japan spur hunt for better radiation care</title>
		<link>http://symptomadvice.com/leaks-in-japan-spur-hunt-for-better-radiation-care/</link>
		<comments>http://symptomadvice.com/leaks-in-japan-spur-hunt-for-better-radiation-care/#comments</comments>
		<pubDate>Fri, 01 Apr 2011 20:34:14 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[anxiety symptoms]]></category>
		<category><![CDATA[countermeasures]]></category>
		<category><![CDATA[dirty bomb]]></category>
		<category><![CDATA[gap]]></category>
		<category><![CDATA[mother nature]]></category>
		<category><![CDATA[nuclear plant workers]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/leaks-in-japan-spur-hunt-for-better-radiation-care/</guid>
		<description><![CDATA[By LAURAN NEERGAARD March 31, 2011 12:00 AM WASHINGTON &#8212; Japan&#8217;s nuclear emergency highlights &#097; &#098;&#105;&#103; medical gap: &#102;&#101;&#119; treatments exist &#116;&#111; help people exposed &#116;&#111; large amounts &#111;&#102; radiation. But some possibilities are in &#116;&#104;&#101; pipeline &#8212; development &#111;&#102; drugs &#116;&#111; treat radiation poisoning, and &#116;&#104;&#101; &#102;&#105;&#114;&#115;&#116; rapid tests &#116;&#111; tell who in &#097; [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/04/1301690054-73.jpg%3Fw%3D640" style="float:left;clear:both;margin:0 15px 15px 0" />By LAURAN NEERGAARD March 31, 2011 12:00 AM
<p>WASHINGTON &#8212; Japan&#8217;s nuclear emergency highlights &#097; &#098;&#105;&#103; medical gap: &#102;&#101;&#119; treatments exist &#116;&#111; help people exposed &#116;&#111; large amounts &#111;&#102; radiation.</p>
<p>But some possibilities are in &#116;&#104;&#101; pipeline &#8212; development &#111;&#102; drugs &#116;&#111; treat radiation poisoning, and &#116;&#104;&#101; &#102;&#105;&#114;&#115;&#116; rapid tests &#116;&#111; tell who in &#097; panicked crowd would &#114;&#101;&#097;&#108;&#108;&#121; need &#116;&#104;&#101;&#109;.</p>
<p>The U.S. calls &#116;&#104;&#101;&#115;&#101; potential products &#8220;countermeasures,&#8221; and they&#8217;re &#112;&#097;&#114;&#116; &#111;&#102; &#116;&#104;&#101; nation&#8217;s preparations against &#097; terrorist attack, such &#097;&#115; &#097; dirty bomb. &#098;&#117;&#116; if they work, they &#099;&#111;&#117;&#108;&#100; be &#117;&#115;&#101;&#102;&#117;&#108; in any kind &#111;&#102; radiation emergency.</p>
<p>&#8220;Thinking &#111;&#102; terrorist events &#105;&#115; &#119;&#104;&#097;&#116; drives &#117;&#115;. Mother Nature can be much &#111;&#102; &#097; terror, too,&#8221; &#115;&#097;&#121;&#115; Dr. Robin Robinson, who heads &#116;&#104;&#101; federal Biomedical Advanced Research and Development Authority, or BARDA, that funds late-stage research &#111;&#102; products &#116;&#104;&#101; government deems most likely &#116;&#111; pan out.</p>
<p>BARDA has invested $164 million for research into anti-radiation treatment candidates &#115;&#105;&#110;&#099;&#101; 2008, and $44 million for radiation testing &#8212; in hopes &#111;&#102; adding such products &#116;&#111; &#116;&#104;&#101; nation&#8217;s emergency medical stockpile soon. That&#8217;s in addition &#116;&#111; research dollars from &#116;&#104;&#101; National Institutes &#111;&#102; Health and &#116;&#104;&#101; Defense Department.</p>
<p>Japan&#8217;s crisis &#8212; where &#108;&#097;&#115;&#116; week &#116;&#119;&#111; nuclear plant workers &#119;&#101;&#114;&#101; hospitalized for radiation burns &#8212; &#105;&#115; sure &#116;&#111; renew attention &#116;&#111; &#097; field that&#8217;s long been overshadowed &#098;&#121; &#116;&#104;&#101; hunt for protections against bioterrorism &#097;&#109;&#111;&#110;&#103; &#116;&#104;&#101; radiation projects considered farthest along:</p>
<p>&#8212; Rapid tests that &#099;&#111;&#117;&#108;&#100; spot dangerous radiation doses with mere finger-pricks &#111;&#102; blood. Already, &#097; prototype machine sits at &#110;&#101;&#119; York&#8217;s Columbia University that &#099;&#111;&#117;&#108;&#100; check thousands &#111;&#102; people.</p>
<p>&#8212; Some drugs &#110;&#111;&#119; &#117;&#115;&#101;&#100; &#116;&#111; help cancer patients boost their infection-fighting blood cells, sold under such names &#097;&#115; Neupogen. They &#109;&#097;&#121; &#100;&#111; &#116;&#104;&#101; same thing for radiation victims.</p>
<p>&#8212; An injection that saved monkeys from highly lethal beams. It &#115;&#101;&#101;&#109;&#115; &#116;&#111; protect &#116;&#104;&#101; body&#8217;s &#116;&#119;&#111; most radiation-sensitive spots, &#116;&#104;&#101; bone marrow and lining &#111;&#102; &#116;&#104;&#101; gut.</p>
<p>Today, &#116;&#104;&#101;&#114;&#101; are only &#097; &#102;&#101;&#119; proven therapies for radiation injuries. Good supportive care &#8212; lots &#111;&#102; fluids, infusions &#111;&#102; blood-clotting platelets, and infection-fighting antibiotics &#8212; &#105;&#115; key for acute radiation syndrome, an overall poisoning that can begin causing symptoms days &#116;&#111; weeks &#097;&#102;&#116;&#101;&#114; &#097; super-high exposure. &#116;&#111; guard against longer-term harm, doses &#111;&#102; potassium iodide can protect against future thyroid cancer &#098;&#121; shielding &#116;&#104;&#101; thyroid from one type &#111;&#102; fallout, radioactive iodine. Other treatments can help &#116;&#104;&#101; body eliminate radioactive cesium and &#097; &#102;&#101;&#119; other isotopes.</p>
<p>Part &#111;&#102; &#116;&#104;&#101; challenge &#105;&#115; radiation&#8217;s variety &#111;&#102; injuries &#8212; burns, bone marrow and gastrointestinal &#100;&#097;&#109;&#097;&#103;&#101;, lung scarring, &#116;&#104;&#101; later-in-life cancer risk. Yet &#111;&#117;&#116;&#115;&#105;&#100;&#101; &#111;&#102; an &#105;&#109;&#109;&#101;&#100;&#105;&#097;&#116;&#101; blast zone where open wounds and burns make injury clear, there&#8217;s no &#102;&#097;&#115;&#116; &#119;&#097;&#121; &#116;&#111; tell who got &#097; &#104;&#117;&#103;&#101; dose.</p>
<p>Those Geiger counter-style monitors &#117;&#115;&#101;&#100; on power-plant workers in Japan? They detect contamination on clothing or skin that &#109;&#105;&#103;&#104;&#116; not enter &#116;&#104;&#101; body, not &#119;&#104;&#097;&#116; &#116;&#104;&#101; body has absorbed, &#115;&#097;&#121;&#115; medical physicist David Brenner, director &#111;&#102; Columbia&#8217;s Center for Radiological Research.</p>
<p>Moreover, previous emergencies &#104;&#097;&#118;&#101; shown that sheer stress can &#099;&#097;&#117;&#115;&#101; nausea and diarrhea that mimic some early symptoms &#111;&#102; radiation sickness in people who weren&#8217;t exposed, he adds.</p>
<p>&#8220;Before &#121;&#111;&#117; can start &#116;&#111; treat people, &#121;&#111;&#117; need &#116;&#111; &#107;&#110;&#111;&#119; &#119;&#104;&#097;&#116; radiation doses they got,&#8221; Brenner &#115;&#097;&#121;&#115;.</p>
<p>Brenner&#8217;s team built &#097; robotic machine named RABiT &#8212; for &#8220;rapid automated biodosimetry tool&#8221; &#8212; that can analyze finger-stick blood samples quickly. &#116;&#104;&#101; eventual goal &#105;&#115; &#116;&#111; be able &#116;&#111; test 30,000 samples in &#097; day. Brenner &#115;&#097;&#121;&#115; federal approval &#105;&#115; &#115;&#116;&#105;&#108;&#108; &#097; &#102;&#101;&#119; years away &#098;&#117;&#116; that &#116;&#104;&#101; prototype &#099;&#111;&#117;&#108;&#100; be &#117;&#115;&#101;&#100; in an emergency if health officials shipped blood samples &#116;&#111; &#104;&#105;&#115; lab.</p>
<p>What &#097;&#098;&#111;&#117;&#116; treatments?</p>
<p>Cells in &#116;&#104;&#101; bone marrow and GI tract are extremely vulnerable &#116;&#111; radiation. They overreact &#116;&#111; &#119;&#104;&#097;&#116; should be reparable &#100;&#097;&#109;&#097;&#103;&#101; and commit cellular suicide, &#115;&#097;&#121;&#115; Dr. Andrei Gudkov &#111;&#102; &#116;&#104;&#101; Roswell Park Cancer Institute.</p>
<p>Gudkov&#8217;s team &#099;&#114;&#101;&#097;&#116;&#101;&#100; &#097; drug based on &#097; protein from normal gut bacteria, named flagellin, that blocks some &#111;&#102; &#116;&#104;&#101; cellular destruction and &#097;&#108;&#115;&#111; stimulates recovery &#111;&#102; remaining cells. It dramatically improved &#116;&#104;&#101; survival &#111;&#102; monkeys treated &#117;&#112; &#116;&#111; 48 hours &#097;&#102;&#116;&#101;&#114; they &#119;&#101;&#114;&#101; zapped. And safety testing in 150 healthy people &#115;&#111; far suggests &#116;&#104;&#101; main side effect &#105;&#115; &#097; flulike reaction, Gudkov &#115;&#097;&#121;&#115;.</p>
<p>BARDA&#8217;s Robinson &#115;&#097;&#121;&#115; that closest &#116;&#111; &#116;&#104;&#101; emergency stockpile &#109;&#097;&#121; be those cancer drugs that spur growth &#111;&#102; infection-fighting blood cells. Later &#116;&#104;&#105;&#115; year, &#104;&#105;&#115; agency &#119;&#105;&#108;&#108; begin &#097; push for research &#116;&#111; prove they &#099;&#111;&#117;&#108;&#100; work similarly in &#097; radiation emergency.</p>
<p>&#8220;There isn&#8217;t going &#116;&#111; be &#097; simple solution &#116;&#111; any &#111;&#102; &#116;&#104;&#105;&#115;,&#8221; cautions Dr. Nelson Chao &#111;&#102; Duke University&#8217;s countermeasures program, who &#097;&#108;&#115;&#111; co-chairs &#116;&#104;&#101; Radiation Injury Treatment Network. &#8220;There &#119;&#105;&#108;&#108; be &#097; lot &#111;&#102; &#108;&#105;&#116;&#116;&#108;&#101; steps &#116;&#111; address &#116;&#104;&#101; plethora &#111;&#102; toxicities that come from radiation.&#8221;</p>
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