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	<title>Symptom Advice .com &#187; gps</title>
	<atom:link href="http://symptomadvice.com/tag/gps/feed/" rel="self" type="application/rss+xml" />
	<link>http://symptomadvice.com</link>
	<description></description>
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		<title>iTriage Mobile Health 2.72 Review</title>
		<link>http://symptomadvice.com/itriage-mobile-health-2-72-review/</link>
		<comments>http://symptomadvice.com/itriage-mobile-health-2-72-review/#comments</comments>
		<pubDate>Sat, 12 Mar 2011 19:17:09 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[medical symptoms]]></category>
		<category><![CDATA[gps]]></category>
		<category><![CDATA[search query]]></category>
		<category><![CDATA[sources of information]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/itriage-mobile-health-2-72-review/</guid>
		<description><![CDATA[If &#121;&#111;&#117; are in a new or unfamiliar area, finding a doctor &#099;&#097;&#110; be a daunting task. iTriage is &#097;&#110; app &#116;&#104;&#097;&#116; uses your phone&#8217;s GPS &#116;&#111; locate nearby doctors, hospitals, clinics, &#097;&#110;&#100; pharmacies. &#105;&#116; &#112;&#114;&#111;&#118;&#105;&#100;&#101;&#115; phone numbers, addresses, &#097;&#110;&#100; options &#116;&#111; call or get directions. &#121;&#111;&#117; &#099;&#097;&#110; &#101;&#118;&#101;&#110; search &#102;&#111;&#114; medical providers based &#111;&#110; [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/03/1299957429-37.jpg" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" />
<p>If &#121;&#111;&#117; are in a new or unfamiliar area, finding a doctor &#099;&#097;&#110; be a daunting task. iTriage is &#097;&#110; app &#116;&#104;&#097;&#116; uses your phone&#8217;s GPS &#116;&#111; locate nearby doctors, hospitals, clinics, &#097;&#110;&#100; pharmacies. &#105;&#116; &#112;&#114;&#111;&#118;&#105;&#100;&#101;&#115; phone numbers, addresses, &#097;&#110;&#100; options &#116;&#111; call or get directions. &#121;&#111;&#117; &#099;&#097;&#110; &#101;&#118;&#101;&#110; search &#102;&#111;&#114; medical providers based &#111;&#110; specialty or the physician&#8217;s name.</p>
<p>You &#099;&#097;&#110; also &#108;&#111;&#111;&#107; up information &#111;&#110; disease symptoms &#097;&#110;&#100; do research &#111;&#110; diseases, treatments, &#097;&#110;&#100; procedures. Search results narrow &#097;&#115; &#121;&#111;&#117; type your query, which saves time.</p>
<p>iTriage features &#097;&#110; &#8220;Emergency&#8221; button &#116;&#104;&#097;&#116; calls 911. I&#8217;m &#110;&#111;&#116; convinced it&#8217;s all &#116;&#104;&#097;&#116; much more useful than &#106;&#117;&#115;&#116; pressing 9-1-1 &#121;&#111;&#117;&#114;&#115;&#101;&#108;&#102;, but it&#8217;s there &#105;&#102; &#121;&#111;&#117; want &#105;&#116;.</p>
<p>Voice-enabled search is also &#097;&#110; option. But in my tests, the accuracy of voice transcriptions varied a lot, &#097;&#110;&#100; I finally gave up &#111;&#110; &#105;&#116; &#119;&#104;&#101;&#110; I realized &#116;&#104;&#097;&#116; typing a search query leads &#116;&#111; &#113;&#117;&#105;&#099;&#107;&#101;&#114; &#097;&#110;&#100; more consistent results.</p>
<p>iTriage contains a wealth of information about &#109;&#097;&#110;&#121; medical conditions &#097;&#110;&#100; treatments, &#097;&#110;&#100; &#105;&#116; &#112;&#114;&#111;&#118;&#105;&#100;&#101;&#115; Web links &#116;&#111; &#101;&#118;&#101;&#110; more sources of information. In &#116;&#104;&#097;&#116; sense, it&#8217;s a &#118;&#101;&#114;&#121; educational app. &#104;&#111;&#119;&#101;&#118;&#101;&#114;, &#109;&#097;&#110;&#121; different medical conditions have &#118;&#101;&#114;&#121; similar symptoms, &#097;&#110;&#100; &#116;&#104;&#105;&#115; app &#115;&#104;&#111;&#117;&#108;&#100; &#110;&#111;&#116; be considered a substitute &#102;&#111;&#114; professional medical attention. It&#8217;s more appropriate &#097;&#115; a way &#116;&#111; learn more about a condition &#111;&#110;&#099;&#101; &#105;&#116; &#104;&#097;&#115; been diagnosed, instead of &#102;&#111;&#114; self-diagnosis.</p>
<p>Also available is a glossary of medical terms, which &#099;&#111;&#117;&#108;&#100; &#104;&#101;&#108;&#112; &#121;&#111;&#117; &#116;&#111; decipher the jargon of the medical establishment.</p>
<p>iTriage is &#109;&#111;&#115;&#116; useful &#097;&#115; a way &#116;&#111; locate &#097;&#110;&#100; contact medical service providers. &#105;&#116; &#112;&#114;&#111;&#118;&#105;&#100;&#101;&#115; the &#105;&#109;&#112;&#111;&#114;&#116;&#097;&#110;&#116; information&#8211;phone number, location, distance, &#097;&#110;&#100; directions&#8211;with a minimum of difficulty. &#102;&#111;&#114; &#116;&#104;&#097;&#116; reason alone, iTriage is &#119;&#101;&#108;&#108; worth installing&#8211;it &#099;&#111;&#117;&#108;&#100; &#099;&#111;&#109;&#101; in handy &#106;&#117;&#115;&#116; &#119;&#104;&#101;&#110; &#121;&#111;&#117; &#110;&#101;&#101;&#100; &#105;&#116;.</p>
<p><strong>Note:</strong> &#121;&#111;&#117; might also want &#116;&#111; check &#111;&#117;&#116; the free pharmaceutical reference app Epocrates.</p></p>
]]></content:encoded>
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		</item>
		<item>
		<title>Could I have Prostatitis?</title>
		<link>http://symptomadvice.com/could-i-have-prostatitis/</link>
		<comments>http://symptomadvice.com/could-i-have-prostatitis/#comments</comments>
		<pubDate>Mon, 21 Feb 2011 02:51:10 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[prostatitis symptoms]]></category>
		<category><![CDATA[gps]]></category>
		<category><![CDATA[headache]]></category>
		<category><![CDATA[pelvis]]></category>
		<category><![CDATA[prostatitis]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/could-i-have-prostatitis/</guid>
		<description><![CDATA[I recently took 10 days worth &#111;&#102; antibiotics &#102;&#111;&#114; &#097; urinary problem I &#097;&#109; having. I &#100;&#105;&#100; not &#115;&#101;&#101; any change in &#109;&#121; symptoms through &#116;&#104;&#101; course &#111;&#102; antibiotics. I &#097;&#109; wondering if I have prostatitis. If I &#100;&#111; have prostatitis &#119;&#111;&#117;&#108;&#100; I &#115;&#101;&#101; any change &#109;&#121; symptoms through &#116;&#104;&#101; &#102;&#105;&#114;&#115;&#116; 10 days &#111;&#102; antibiotics? [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/02/1298256670-11.jpg" style="clear:both;clear:both;margin:0 15px 15px 0" />
<p>I recently took 10 days worth &#111;&#102; antibiotics &#102;&#111;&#114; &#097; urinary problem I &#097;&#109; having. I &#100;&#105;&#100; not &#115;&#101;&#101; any change in &#109;&#121; symptoms through &#116;&#104;&#101; course &#111;&#102; antibiotics. I &#097;&#109; wondering if I have prostatitis. If I &#100;&#111; have prostatitis &#119;&#111;&#117;&#108;&#100; I &#115;&#101;&#101; any change &#109;&#121; symptoms through &#116;&#104;&#101; &#102;&#105;&#114;&#115;&#116; 10 days &#111;&#102; antibiotics? I know &#116;&#104;&#101; treatment &#102;&#111;&#114; prostatitis is 6 &#116;&#111; 12 weeks. </p>
<p>You might look into Chronic Pelvic Pain Syndrome, CPPS. &#116;&#104;&#101;&#114;&#101; is &#097; book called Headache in &#116;&#104;&#101; Pelvis, &#097;&#110;&#100; &#097; group &#111;&#102; guys &#119;&#105;&#116;&#104; similar symptoms &#097;&#116;:</p>
<p> chronicprostatitis.com </p>
<p>I went &#116;&#111; several GPs &#111;&#118;&#101;&#114; &#097; period &#111;&#102; several years &#102;&#111;&#114; what turned &#111;&#117;&#116; &#116;&#111; be prostatitis. They gave me antibiotics, but nothing &#115;&#101;&#101;&#109;&#101;&#100; &#116;&#111; &#104;&#101;&#108;&#112;. &#116;&#104;&#101;&#110; I went &#116;&#111; &#097; urologist &#119;&#104;&#111; took x-rays. Seeing &#116;&#104;&#097;&#116; several courses &#111;&#102; antibiotics &#104;&#097;&#100; not touched &#116;&#104;&#101; problem, he &#104;&#097;&#100; &#116;&#111; go in &#116;&#104;&#101;&#114;&#101; &#119;&#105;&#116;&#104; &#097; rod &#097;&#110;&#100; stir &#116;&#104;&#105;&#110;&#103;&#115; up &#097; bit. It didn&#039;t hurt &#119;&#104;&#101;&#110; he &#100;&#105;&#100; it &#097;&#115; he &#100;&#105;&#100; &#097; local anesthetic, but he told me &#116;&#111; sit &#100;&#111;&#119;&#110; &#116;&#111; pee &#102;&#111;&#114; several days, &#101;&#108;&#115;&#101; I &#119;&#111;&#117;&#108;&#100; &#112;&#114;&#111;&#098;&#097;&#098;&#108;&#121; fall &#100;&#111;&#119;&#110; &#102;&#114;&#111;&#109; &#116;&#104;&#101; pain. &#116;&#104;&#097;&#116; procedure &#097;&#110;&#100; more antibiotics &#100;&#105;&#100; &#116;&#104;&#101; trick &#097;&#110;&#100; I &#097;&#109; pain free &#102;&#111;&#114; &#109;&#097;&#110;&#121; years and<br /> never &#104;&#097;&#100; &#116;&#104;&#101; problem &#097;&#103;&#097;&#105;&#110;. I &#097;&#109; not &#115;&#097;&#121;&#105;&#110;&#103; &#121;&#111;&#117; will need anything like this, but &#109;&#121; advice is &#116;&#111; go &#115;&#101;&#101; &#097; urologist if &#121;&#111;&#117;&#114; GP hasn&#039;t &#098;&#101;&#101;&#110; able &#116;&#111; &#104;&#101;&#108;&#112; &#121;&#111;&#117;.</p></p>
]]></content:encoded>
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		</item>
		<item>
		<title>How long before I am free of codeine addiction withdrawal symptoms?</title>
		<link>http://symptomadvice.com/how-long-before-i-am-free-of-codeine-addiction-withdrawal-symptoms/</link>
		<comments>http://symptomadvice.com/how-long-before-i-am-free-of-codeine-addiction-withdrawal-symptoms/#comments</comments>
		<pubDate>Sat, 19 Feb 2011 14:51:12 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[exhaustion symptoms]]></category>
		<category><![CDATA[anxiety]]></category>
		<category><![CDATA[co codamol]]></category>
		<category><![CDATA[gps]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/how-long-before-i-am-free-of-codeine-addiction-withdrawal-symptoms/</guid>
		<description><![CDATA[Six weeks &#097;&#103;&#111;, I realised I had &#103;&#111;&#116; myself addicted to Boots own paracetamol &#097;&#110;&#100; codeine tablets &#8211; 6/8 &#097; day taken regular as clockwork &#102;&#111;&#114; &#097;&#116; least eight years. I stopped immediately &#097;&#110;&#100; &#119;&#101;&#110;&#116; &#099;&#111;&#108;&#100; turkey. I suffered all &#111;&#102; the classic opiate withdrawal symptoms: muscle ache, tiredness &#097;&#110;&#100; exhaustion, sneezing, itching, yawning &#097;&#110;&#100; [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/02/1298127072-31.jpg" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" />
<p>Six weeks &#097;&#103;&#111;, I realised I had &#103;&#111;&#116; myself addicted to Boots own paracetamol &#097;&#110;&#100; codeine tablets &#8211; 6/8 &#097; day taken regular as clockwork &#102;&#111;&#114; &#097;&#116; least eight years. I stopped immediately &#097;&#110;&#100; &#119;&#101;&#110;&#116; &#099;&#111;&#108;&#100; turkey. I suffered all &#111;&#102; the classic opiate withdrawal symptoms: muscle ache, tiredness &#097;&#110;&#100; exhaustion, sneezing, itching, yawning &#097;&#110;&#100; anxiety, but I think the &#119;&#111;&#114;&#115;&#116; is over (NB &#109;&#121; GP said &#104;&#101; would not have recommended &#099;&#111;&#108;&#100; turkey but said now I had started I &#115;&#104;&#111;&#117;&#108;&#100; carry on). I still get &#118;&#101;&#114;&#121; tired &#097;&#110;&#100; exhausted &#097;&#110;&#100; yawn &#097; lot, &#097;&#110;&#100; I am sick &#111;&#102; &#105;&#116;. Can &#097;&#110;&#121;&#111;&#110;&#101; tell me &#119;&#104;&#101;&#110; I &#114;&#101;&#097;&#115;&#111;&#110;&#097;&#098;&#108;&#121; expect to be &#098;&#097;&#099;&#107; to normal &#097;&#110;&#100; withdrawal symptom free?</p>
<p>I am afraid the potential &#102;&#111;&#114; addiction &#111;&#102; &#098;&#111;&#116;&#104; over the counter co-codamol &#097;&#110;&#100; the prescribed tablets, &#115;&#111;&#109;&#101; &#111;&#102; which have even more codeine, is grossly underestimated &#098;&#121; the medical profession. You have &#109;&#121; sympathy. I fought &#097; pretty thankless battle to get prescribing locally reduced, even &#119;&#105;&#116;&#104; the &#104;&#101;&#108;&#112; &#111;&#102; the local pharmacy prescribing advisor, &#102;&#111;&#114; 15 years, before I retired. </p>
<p> They &#097;&#114;&#101; &#111;&#102;&#116;&#101;&#110; started in hospital &#119;&#104;&#101;&#110; patients &#097;&#114;&#101; in patients, &#097;&#110;&#100; then continued &#098;&#121; the GPs indefinitely!</p>
<p> There &#097;&#114;&#101; no easy pharmacological alternatives to aid the withdrawal process, &#097;&#110;&#100; fo this particular drug, I &#117;&#115;&#117;&#097;&#108;&#108;&#121; advised gradual withdrawal. &#099;&#111;&#108;&#100; turkey is unpleasant but &#111;&#102;&#116;&#101;&#110; useful. &#117;&#110;&#102;&#111;&#114;&#116;&#117;&#110;&#097;&#116;&#101;&#108;&#121; doctors have &#098;&#101;&#101;&#110; taught &#116;&#104;&#097;&#116; &#105;&#116; is not &#097; PC method &#111;&#102; dealing &#119;&#105;&#116;&#104; addiction.</p>
<p> However &#119;&#104;&#101;&#110; I worked &#102;&#111;&#114; the Scottish Prison Service as &#097; PMO, &#105;&#116; &#119;&#097;&#115; the method preferred &#098;&#121; &#109;&#097;&#110;&#121; opiate addicts!</p>
<p> Sorry I &#097;&#108;&#109;&#111;&#115;&#116; forgot to &#097;&#110;&#115;&#119;&#101;&#114; your &#113;&#117;&#101;&#115;&#116;&#105;&#111;&#110;! I would have &#116;&#104;&#111;&#117;&#103;&#104;&#116; physical withdrawal &#115;&#104;&#111;&#117;&#108;&#100; not &#116;&#097;&#107;&#101; more &#116;&#104;&#097;&#110; &#097; week, &#117;&#110;&#102;&#111;&#114;&#116;&#117;&#110;&#097;&#116;&#101;&#108;&#121; psychological withdrawal has no real measurable timescale.</p>
<p>I&#039;ve &#098;&#101;&#101;&#110; there although mine &#119;&#097;&#115; only &#097; 6 month usage. I weaned myself &#100;&#111;&#119;&#110; over 2 weeks &#097;&#110;&#100; I guess &#105;&#116; to OK &#097; &#103;&#111;&#111;&#100; 2-3 months after &#115;&#116;&#111;&#112;&#112;&#105;&#110;&#103; completely before I started feeling like I had the same energy levels. &#105;&#116; &#109;&#105;&#103;&#104;&#116; be longer &#102;&#111;&#114; you as you were &#111;&#110; them &#115;&#111; long but ask your Dr if &#105;&#116;&#115; ok to &#117;&#115;&#101; &#097;&#110; energy drink mid day to pep you up although I guess this could be swapping &#111;&#110;&#101; fix &#102;&#111;&#114; &#097;&#110;&#111;&#116;&#104;&#101;&#114;. &#105;&#116; could also be &#116;&#104;&#097;&#116; youre 8 years older &#097;&#110;&#100; would have &#098;&#101;&#101;&#110; finding yourself more tired even without having become addicted&#8230;you just wouldnt have noticed &#105;&#116; creeping up &#111;&#110; you over 8 years. </p>
<p> I think there &#110;&#101;&#101;&#100;&#115; to be &#097; much &#098;&#105;&#103;&#103;&#101;&#114; warning &#111;&#110; these paracetamol/codeine tablets to alert people. &#109;&#121; brand were &#097; chemists own brand &#097;&#110;&#100; carried no warning but I &#098;&#111;&#117;&#103;&#104;&#116; them from Lloyd&#039;s the &#111;&#110;&#101; day &#097;&#110;&#100; I noticed &#097; warning, that&#039;s &#119;&#104;&#101;&#110; I realised I &#119;&#097;&#115; probably &#097; &#108;&#105;&#116;&#116;&#108;&#101; dependant &#111;&#110; them.</p>
<p> Best &#111;&#102; luck</p></p>
]]></content:encoded>
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		<title>Final NICE Appraisal Recommends Improved Access to Treatment and Care of People With Early Alzheimer´s Disease</title>
		<link>http://symptomadvice.com/final-nice-appraisal-recommends-improved-access-to-treatment-and-care-of-people-with-early-alzheimer%c2%b4s-disease/</link>
		<comments>http://symptomadvice.com/final-nice-appraisal-recommends-improved-access-to-treatment-and-care-of-people-with-early-alzheimer%c2%b4s-disease/#comments</comments>
		<pubDate>Tue, 25 Jan 2011 11:17:09 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[crohn s symptoms]]></category>
		<category><![CDATA[clinical excellence]]></category>
		<category><![CDATA[general practitioners]]></category>
		<category><![CDATA[gps]]></category>
		<category><![CDATA[health]]></category>
		<category><![CDATA[london]]></category>
		<category><![CDATA[nice guidance]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/final-nice-appraisal-recommends-improved-access-to-treatment-and-care-of-people-with-early-alzheimer%c2%b4s-disease/</guid>
		<description><![CDATA[LONDON, January 18, 2011 /PRNewswire/ &#8212; &#116;&#104;&#101; National Institute &#102;&#111;&#114; Health and Clinical Excellence (NICE) today published &#105;&#116;&#115; final appraisal determination containing final recommendations on &#116;&#104;&#101; &#117;&#115;&#101; of specific treatments &#102;&#111;&#114; Alzheimer´s disease. &#116;&#104;&#101; new ruling means Alzheimer´s patients &#119;&#105;&#108;&#108; &#110;&#111;&#119; have access to treatment &#102;&#114;&#111;&#109; &#116;&#104;&#101; earliest stage of &#116;&#104;&#101; disease.[1]* A survey conducted [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/01/1295954229-67.jpg" style="clear:both;clear:both;margin:0 15px 15px 0" />
<p>LONDON, January 18, 2011 /PRNewswire/ &#8212; &#116;&#104;&#101; National Institute &#102;&#111;&#114; Health and Clinical Excellence (NICE) today published &#105;&#116;&#115; final appraisal determination containing final recommendations on &#116;&#104;&#101; &#117;&#115;&#101; of specific treatments &#102;&#111;&#114; Alzheimer´s disease. &#116;&#104;&#101; new ruling means Alzheimer´s patients &#119;&#105;&#108;&#108; &#110;&#111;&#119; have access to treatment &#102;&#114;&#111;&#109; &#116;&#104;&#101; earliest stage of &#116;&#104;&#101; disease.[1]* </p>
<p> A survey conducted among general practitioners across &#116;&#104;&#101; UK &#104;&#097;&#115; suggested &#116;&#104;&#097;&#116; &#116;&#104;&#101; new recommendations &#119;&#105;&#108;&#108; &#103;&#105;&#118;&#101; Doctors[2] a strong reason to diagnose and treat this devastating disease early. &#105;&#116; highlighted &#116;&#104;&#097;&#116; nearly two thirds (64.1%) of GPs &#098;&#101;&#108;&#105;&#101;&#118;&#101; &#116;&#104;&#097;&#116; &#116;&#104;&#101;&#105;&#114; detection and diagnosis of mild Alzheimer´s disease patients &#119;&#105;&#108;&#108; improve as a result of &#116;&#104;&#101; NICE guidance. Until &#110;&#111;&#119; diagnosing &#116;&#104;&#101; condition early &#104;&#097;&#115; been difficult &#102;&#111;&#114; GPs, as &#116;&#104;&#101; guidelines previously recommended treatment only &#102;&#111;&#114; patients with moderate or severe Alzheimer´s disease. 70.2% of GPs surveyed &#098;&#101;&#108;&#105;&#101;&#118;&#101; &#116;&#104;&#097;&#116; &#116;&#104;&#101;&#105;&#114; management of Alzheimer´s disease &#119;&#105;&#108;&#108; change as a result of &#116;&#104;&#101; new guidance with &#111;&#118;&#101;&#114; half (57.9%) of GPs stating &#116;&#104;&#097;&#116; they &#119;&#111;&#117;&#108;&#100; &#098;&#101; &#108;&#105;&#107;&#101;&#108;&#121; to recall patients with mild Alzheimer´s previously denied treatment &#102;&#111;&#114; reassessment. This should help &#109;&#111;&#114;&#101; people with early disease &#103;&#101;&#116; access to specialist care &#098;&#121; being referred to a memory service &#102;&#111;&#114; assessment. A total of 40.7% of doctors &#097;&#108;&#115;&#111; &#116;&#104;&#111;&#117;&#103;&#104;&#116; &#116;&#104;&#097;&#116; &#116;&#104;&#101;&#105;&#114; prescribing of AChEIs &#119;&#111;&#117;&#108;&#100; change as a result of &#116;&#104;&#101; NICE recommendations. </p>
<p> &#8220;This &#105;&#115; great news &#102;&#111;&#114; people with Alzheimer´s disease and &#116;&#104;&#101;&#105;&#114; families &#098;&#101;&#099;&#097;&#117;&#115;&#101; we &#119;&#105;&#108;&#108; &#110;&#111;&#119; &#098;&#101; able to offer effective drug treatment in mild, moderate and severe Alzheimer´s disease. &#102;&#111;&#114; &#101;&#120;&#097;&#109;&#112;&#108;&#101;, patients with mild disease &#119;&#105;&#108;&#108; &#097;&#116; last &#098;&#101; able to &#103;&#101;&#116; access to early, cost-effective treatment &#097;&#116; &#116;&#104;&#101; point of diagnosis &#8211; treatment &#116;&#104;&#097;&#116; can potentially help to relieve &#116;&#104;&#101; symptoms in these patients&#8221;, &#115;&#097;&#121;&#115; Professor Roy Jones &#102;&#114;&#111;&#109; &#116;&#104;&#101; Research Institute &#102;&#111;&#114; &#116;&#104;&#101; Care of Older People (RICE), Royal United Hospital, Bath, UK. &#8220;Previously &#105;&#116; was difficult to &#115;&#101;&#101; patients with mild disease and ask them to &#099;&#111;&#109;&#101; &#098;&#097;&#099;&#107; &#119;&#104;&#101;&#110; &#116;&#104;&#101;&#105;&#114; condition worsened &#098;&#101;&#102;&#111;&#114;&#101; we were able to prescribe drugs &#116;&#104;&#097;&#116; &#099;&#111;&#117;&#108;&#100; improve &#116;&#104;&#101;&#105;&#114; symptoms. This new ruling &#119;&#105;&#108;&#108; help &#107;&#101;&#101;&#112; patients as independent as &#112;&#111;&#115;&#115;&#105;&#098;&#108;&#101; &#102;&#111;&#114; as long as &#112;&#111;&#115;&#115;&#105;&#098;&#108;&#101;.&#8221; </p>
<p> &#116;&#104;&#101; new survey data &#097;&#108;&#115;&#111; revealed &#116;&#104;&#097;&#116;, unfortunately 29.6 % of GPs surveyed were unaware of &#116;&#104;&#101; preliminary recommendations published &#098;&#121; NICE on &#116;&#104;&#101; &#117;&#115;&#101; of AChEIs in patients with Alzheimer´s disease and 55.5% &#098;&#101;&#108;&#105;&#101;&#118;&#101; &#116;&#104;&#097;&#116; there are inadequate protocols / materials in &#112;&#108;&#097;&#099;&#101; to effectively help them diagnose people &#115;&#104;&#111;&#119;&#105;&#110;&#103; early signs of disease. In addition, &#116;&#104;&#101; survey revealed &#116;&#104;&#097;&#116; 86.7% of GPs &#098;&#101;&#108;&#105;&#101;&#118;&#101; &#116;&#104;&#097;&#116; families and carers of patients with Alzheimer´s disease do &#110;&#111;&#116; have adequate support to recognise and manage &#116;&#104;&#101; early signs of &#116;&#104;&#101; disease. &#105;&#116; &#105;&#115; vital &#116;&#104;&#097;&#116; Alzheimer´s disease &#105;&#115; diagnosed as early as &#112;&#111;&#115;&#115;&#105;&#098;&#108;&#101;, as having &#097;&#110; early diagnosis, starting treatment and putting lifestyle modifications in &#112;&#108;&#097;&#099;&#101; in &#116;&#104;&#101; early stages of &#116;&#104;&#101; disease can help individuals prepare &#102;&#111;&#114; &#116;&#104;&#101; future.[3] Greater awareness &#105;&#115; needed &#097;&#109;&#111;&#110;&#103;&#115;&#116; patients, carers and GPs of &#116;&#104;&#101; early treatment options &#110;&#111;&#119; available to them which &#099;&#111;&#117;&#108;&#100; lead to &#098;&#101;&#116;&#116;&#101;&#114; outcomes &#102;&#111;&#114; &#116;&#104;&#101; patient and carers. </p>
<p> *Additional information on &#116;&#104;&#101; NICE guidance1 </p>
<p> 1.1 &#116;&#104;&#101; three acetylcholinesterase (AChE) inhibitors (donepezil, galantamine and rivastigmine) are recommended as options &#102;&#111;&#114; managing mild to moderate Alzheimer´s disease &#117;&#110;&#100;&#101;&#114; all of &#116;&#104;&#101; conditions &#115;&#112;&#101;&#099;&#105;&#102;&#105;&#101;&#100; in 1.3 and 1.4. </p>
<p> 1.2 Memantine &#105;&#115; recommended as &#097;&#110; option &#102;&#111;&#114; managing Alzheimer´s disease &#102;&#111;&#114; people with: moderate Alzheimer´s disease &#119;&#104;&#111; are intolerant of or have a contraindication to AChE inhibitors or severe Alzheimer´s disease. </p>
<p> 1.3 Treatment should &#098;&#101; &#117;&#110;&#100;&#101;&#114; &#116;&#104;&#101; conditions &#115;&#112;&#101;&#099;&#105;&#102;&#105;&#101;&#100; in 1.3. </p>
<p> &#8211; Only specialists in &#116;&#104;&#101; care of patients with dementia (that &#105;&#115;, psychiatrists including those specialising in learning disability, neurologists, and physicians specialising in &#116;&#104;&#101; care of older people) should initiate treatment. Carers´ views on &#116;&#104;&#101; patient´s condition &#097;&#116; baseline should &#098;&#101; sought. &#8211; Treatment should &#098;&#101; continued only &#119;&#104;&#101;&#110; &#105;&#116; &#105;&#115; considered to &#098;&#101; having a worthwhile effect on cognitive, global, functional or behavioural symptoms. &#8211; Patients &#119;&#104;&#111; continue on treatment should &#098;&#101; reviewed regularly using cognitive, global, functional and behavioural assessment. Treatment should &#098;&#101; reviewed &#098;&#121; &#097;&#110; appropriate specialist team, unless there are locally agreed protocols &#102;&#111;&#114; shared care. Carers´ views on &#116;&#104;&#101; patient´s condition &#097;&#116; follow-up should &#098;&#101; sought.
<p> 1.4 &#105;&#102; prescribing &#097;&#110; AChE inhibitor (donepezil, galantamine or rivastigmine), treatment should normally &#098;&#101; &#115;&#116;&#097;&#114;&#116;&#101;&#100; with &#116;&#104;&#101; drug with &#116;&#104;&#101; lowest acquisition cost (taking into account required daily dose and &#116;&#104;&#101; price &#112;&#101;&#114; dose &#111;&#110;&#099;&#101; shared care &#104;&#097;&#115; started). &#104;&#111;&#119;&#101;&#118;&#101;&#114;, &#097;&#110; alternative AChE inhibitor &#099;&#111;&#117;&#108;&#100; &#098;&#101; prescribed &#105;&#102; &#105;&#116; &#105;&#115; considered appropriate &#119;&#104;&#101;&#110; &#116;&#097;&#107;&#105;&#110;&#103; into account adverse event profile, expectations about adherence, medical comorbidity, possibility of drug interactions and dosing profiles. </p>
<p> &#102;&#111;&#114; &#116;&#104;&#101; &#102;&#117;&#108;&#108; guidance, &#112;&#108;&#101;&#097;&#115;&#101; visit: guidance.nice.org.uk/</p>
<p> &#099;&#117;&#114;&#114;&#101;&#110;&#116;&#108;&#121;, there are around 820,000 people living with Alzheimer´s and other dementias in &#116;&#104;&#101; UK, [4] including &#097;&#110; estimated 575,000 sufferers in England and 37,000 in Wales.[5] Alzheimer´s disease &#105;&#115; &#116;&#104;&#101; &#109;&#111;&#115;&#116; common form of dementia, affecting 62% of dementia patients in &#116;&#104;&#101; UK.[5] This irreversible, progressive brain disorder gradually destroys memory, reasoning and thinking skills, and &#109;&#097;&#121; eventually leave patients unable to carry out even &#116;&#104;&#101; simplest tasks.[6] Alzheimer´s disease &#104;&#097;&#115; impacts in many ways including physical, mental, nursing, medical and social impacts.[1] &#100;&#101;&#115;&#112;&#105;&#116;&#101; &#105;&#116;&#115; burden, Alzheimer´s remains a &#114;&#101;&#108;&#097;&#116;&#105;&#118;&#101;&#108;&#121; overlooked disease. Just 2.5% of &#116;&#104;&#101; government´s medical research budget &#105;&#115; devoted to dementia; in contrast a quarter &#105;&#115; allocated to cancer research.[7] </p>
<p> Eisai &#105;&#115; one of &#116;&#104;&#101; worlds leading research-based pharmaceutical companies &#116;&#104;&#097;&#116; &#104;&#097;&#115; defined &#105;&#116;&#115; corporate mission as &#8220;giving first &#116;&#104;&#111;&#117;&#103;&#104;&#116; to patients and &#116;&#104;&#101;&#105;&#114; families and to increasing &#116;&#104;&#101; benefits health care provides, &#8221; which we &#099;&#097;&#108;&#108; human health care (hhc). </p>
<p> Eisai concentrates &#105;&#116;&#115; research activities in three key areas: </p>
<p> &#8211; Integrative Neuroscience, including: Alzheimer´s disease, multiple sclerosis, neuropathic pain, epilepsy, depression &#8211; Integrative Oncology including: anticancer therapies; tumour regression, tumour suppression, antibodies, etc and supportive cancer therapies; pain relief, nausea &#8211; Vascular/Immunological reaction including: acute coronary syndrome, atherothrombotic disease, sepsis, rheumatoid arthritis, psoriasis, Crohn´s disease
<p> With operations in &#116;&#104;&#101; U.S., Asia, Europe and &#105;&#116;&#115; domestic home market of Japan, we &#101;&#109;&#112;&#108;&#111;&#121; &#109;&#111;&#114;&#101; &#116;&#104;&#097;&#110; 11,000 people worldwide. </p>
<p> About Pfizer: Working Together &#102;&#111;&#114; a Healthier World(TM) </p>
<p> &#097;&#116; Pfizer, we apply science and &#111;&#117;&#114; global resources to improve health and well-being &#097;&#116; &#101;&#118;&#101;&#114;&#121; stage of life. We strive to set &#116;&#104;&#101; standard &#102;&#111;&#114; quality, safety and value in &#116;&#104;&#101; discovery, development and manufacturing of medicines &#102;&#111;&#114; people and animals. &#111;&#117;&#114; diversified global health care portfolio includes human and animal biologic and small molecule medicines and vaccines, as well as nutritional products and many of &#116;&#104;&#101; world´s best-known consumer products. &#101;&#118;&#101;&#114;&#121; day, Pfizer colleagues work to advance wellness, prevention, treatments and cures &#116;&#104;&#097;&#116; challenge &#116;&#104;&#101; &#109;&#111;&#115;&#116; feared diseases of &#111;&#117;&#114; time. Consistent with &#111;&#117;&#114; responsibility as &#116;&#104;&#101; world´s leading biopharmaceutical company, we &#097;&#108;&#115;&#111; collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around &#116;&#104;&#101; world. &#102;&#111;&#114; &#109;&#111;&#114;&#101; &#116;&#104;&#097;&#110; 150 years, Pfizer &#104;&#097;&#115; worked to make a difference &#102;&#111;&#114; all &#119;&#104;&#111; rely on &#117;&#115;. </p>
<p> In &#116;&#104;&#101; UK, Pfizer &#104;&#097;&#115; &#105;&#116;&#115; European R&amp;D headquarters &#097;&#116; Sandwich and &#105;&#116;&#115; UK business headquarters in Surrey, and &#105;&#115; &#116;&#104;&#101; major supplier of medicines to &#116;&#104;&#101; NHS. To learn &#109;&#111;&#114;&#101; about &#111;&#117;&#114; commitments, &#112;&#108;&#101;&#097;&#115;&#101; visit &#117;&#115; &#097;&#116; pfizer.co.uk. </p>
<p> [1] National Institute &#102;&#111;&#114; Health and Clinical Excellence, Final Appraisal Determination &#8211; Donepezil, galantamine, rivastigmine and memantine &#102;&#111;&#114; &#116;&#104;&#101; treatment of Alzheimer´s disease (review of NICE technology appraisal guidance 111) </p>
<p> [2] Opinion Health survey data. Total sample size was 200 GPs in &#116;&#104;&#101; UK. Online internet-based survey fieldwork undertaken &#098;&#101;&#116;&#119;&#101;&#101;&#110; 13th &#8211; 16th December 2010. Eisai Europe and Pfizer Ltd. Data on File </p>
<p> [3] Doraiswamy PM, Steffens DC, Pitchumoni S, Tabrizi S. Early Recognition of Alzheimer´s disease: &#119;&#104;&#097;&#116; &#105;&#115; consensual? &#119;&#104;&#097;&#116; &#105;&#115; controversial? &#119;&#104;&#097;&#116; &#105;&#115; practical? J Clin Psychiatry. 1998;59 (suppl. 13):6-18. </p>
<p> [4] Alzheimer´s Research Trust -Dementia 2010. Available &#097;&#116;: dementia2010.org/reports/Dementia2010Full.pdf. Last accessed Jan 2011 </p>
<p> [5] Alzheimer Society. Available &#097;&#116;: alzheimers.org.uk Last accessed Jan 2011 </p>
<p> [6] National Institute on Aging (NIA). Alzheimer´s Disease Factsheet. NIH Publication &#110;&#111; 08-6423. Reprinted February 2010 </p>
<p> [7] Alzheimer´s Research Trust. Available &#097;&#116;: alzheimers-research.org.uk/info/statistics/ Last accessed Jan 2011 </p>
<p>Eisai Europe Limited and Pfizer Limited</p>
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