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	<title>Symptom Advice .com &#187; ivf</title>
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		<title>Herald Scotland</title>
		<link>http://symptomadvice.com/herald-scotland/</link>
		<comments>http://symptomadvice.com/herald-scotland/#comments</comments>
		<pubDate>Wed, 02 Feb 2011 18:00:15 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[fibrosis symptoms]]></category>
		<category><![CDATA[cystic fibrosis]]></category>
		<category><![CDATA[ivf]]></category>
		<category><![CDATA[shock]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/herald-scotland/</guid>
		<description><![CDATA[A Scottish couple &#104;&#097;&#118;&#101; become the &#102;&#105;&#114;&#115;&#116; in the country to undergo groundbreaking fertility screening to prevent &#116;&#104;&#101;&#105;&#114; son &#098;&#101;&#105;&#110;&#103; born &#119;&#105;&#116;&#104; cystic fibrosis. Lee &#097;&#110;&#100; Stephen Smith &#119;&#101;&#114;&#101; one of &#116;&#104;&#114;&#101;&#101; couples &#103;&#105;&#118;&#101;&#110; the IVF-style tests, &#119;&#104;&#105;&#099;&#104; attempt to screen &#102;&#111;&#114; single-gene disorders. Baby Thomas &#119;&#097;&#115; born on November 14 last year &#097;&#110;&#100;, after [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/02/1296669615-61.jpg" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" />
<p><strong>A Scottish couple &#104;&#097;&#118;&#101; become the &#102;&#105;&#114;&#115;&#116; in the country to undergo groundbreaking fertility screening to prevent &#116;&#104;&#101;&#105;&#114; son &#098;&#101;&#105;&#110;&#103; born &#119;&#105;&#116;&#104; cystic fibrosis.</strong></p>
<p>Lee &#097;&#110;&#100; Stephen Smith &#119;&#101;&#114;&#101; one of &#116;&#104;&#114;&#101;&#101; couples &#103;&#105;&#118;&#101;&#110; the IVF-style tests, &#119;&#104;&#105;&#099;&#104; attempt to screen &#102;&#111;&#114; single-gene disorders.</p>
<p>Baby Thomas &#119;&#097;&#115; born on November 14 last year &#097;&#110;&#100;, after a final set of tests, doctors confirmed &#104;&#101; &#100;&#111;&#101;&#115; &#110;&#111;&#116; &#104;&#097;&#118;&#101; the condition.</p>
<p>Stephen, 37, said when &#116;&#104;&#101;&#105;&#114; &#102;&#105;&#114;&#115;&#116; child, four-year-old Eden, &#119;&#097;&#115; diagnosed &#119;&#105;&#116;&#104; cystic fibrosis, the pair &#104;&#097;&#100; no idea they &#119;&#101;&#114;&#101; &#098;&#111;&#116;&#104; carriers of the &#8220;faulty gene&#8221; &#119;&#104;&#105;&#099;&#104; &#099;&#097;&#117;&#115;&#101;&#115; &#105;&#116;.</p>
<p>He said: &#8220;There &#105;&#115; no history of &#105;&#116; in &#101;&#105;&#116;&#104;&#101;&#114; of our families so we didn&#8217;t suspect a thing.&#8221;</p>
<p>The couple, from East Lothian, decided on the treatment when trying &#102;&#111;&#114; a second child, as they said the one-in-four chance of &#116;&#104;&#101;&#109; having &#097;&#110;&#111;&#116;&#104;&#101;&#114; baby &#119;&#105;&#116;&#104; the condition &#119;&#097;&#115; &#116;&#111;&#111; big a risk.</p>
<p>Lee, 40, said: &#8220;We probably spent the &#102;&#105;&#114;&#115;&#116; &#116;&#104;&#114;&#101;&#101; years in shock, &#097;&#110;&#100; trying to &#109;&#097;&#107;&#101; &#115;&#117;&#114;&#101; we could deal &#119;&#105;&#116;&#104; Eden&#8217;s symptoms.</p>
<p>&#8220;Although she &#105;&#115; generally quite well we &#104;&#097;&#118;&#101; to &#098;&#101; careful she doesn&#8217;t catch &#097;&#110;&#121; infections, as her immune &#115;&#121;&#115;&#116;&#101;&#109; isn&#8217;t as able to fight infection.</p>
<p>&#8220;Having two children &#119;&#105;&#116;&#104; cystic fibrosis &#099;&#097;&#110; &#109;&#101;&#097;&#110; they constantly keep passing infections back &#097;&#110;&#100; forth.</p>
<p>&#8220;We decided we couldn&#8217;t risk our children&#8217;s health &#108;&#105;&#107;&#101; that.</p>
<p>&#8220;Looking after one child &#119;&#104;&#111; has cystic fibrosis &#099;&#097;&#110; &#098;&#101; tough at times, &#098;&#117;&#116; if &#121;&#111;&#117; &#104;&#097;&#100; two children &#119;&#105;&#116;&#104; the condition, trying to ensure &#098;&#111;&#116;&#104; &#119;&#101;&#114;&#101; kept well &#097;&#110;&#100; didn&#8217;t cross-infect &#101;&#097;&#099;&#104; other &#119;&#111;&#117;&#108;&#100; &#098;&#101; much &#109;&#111;&#114;&#101; difficult.</p>
<p>&#8220;We knew we wanted &#097;&#110;&#111;&#116;&#104;&#101;&#114; child, &#097;&#110;&#100; &#119;&#101;&#114;&#101; &#114;&#101;&#097;&#108;&#108;&#121; &#112;&#108;&#101;&#097;&#115;&#101;&#100; when we got the opportunity to undergo &#116;&#104;&#105;&#115; treatment.</p>
<p>&#8220;We &#119;&#101;&#114;&#101; &#114;&#101;&#097;&#108;&#108;&#121; lucky that &#105;&#116; worked &#102;&#111;&#114; us &#102;&#105;&#114;&#115;&#116; time. I &#119;&#097;&#115; &#107;&#101;&#101;&#110; to &#103;&#101;&#116; &#116;&#104;&#105;&#110;&#103;&#115; moving as &#109;&#121; biological clock &#119;&#097;&#115; ticking.&#8221;</p>
<p>Stephen added: &#8220;We&#8217;ve been lucky in &#109;&#097;&#110;&#121; ways because no other children at Eden&#8217;s school &#104;&#097;&#118;&#101; cystic fibrosis, so the chance of cross-infection there &#105;&#115; low.</p>
<p>&#8220;&#098;&#117;&#116; we &#097;&#108;&#119;&#097;&#121;&#115; wanted her to &#104;&#097;&#118;&#101; a younger brother or sister while keeping &#116;&#104;&#101;&#109; &#098;&#111;&#116;&#104; as healthy as possible.&#8221;</p>
<p>The Western General Hospital in Edinburgh &#105;&#115; Scotland&#8217;s &#111;&#110;&#108;&#121; hospital to offer the pre-implantation testing, &#097;&#110;&#100; &#099;&#097;&#110; &#116;&#097;&#107;&#101; up to 15 couples a year.</p>
<p>Around one in 25 people carries the faulty gene, &#098;&#117;&#116; &#105;&#116; &#105;&#115; &#111;&#110;&#108;&#121; when two carriers &#104;&#097;&#118;&#101; a child together that the condition &#099;&#097;&#110; &#098;&#101; passed on.</p>
<p>There &#105;&#115; a one in &#102;&#111;&#117;&#114; chance that a child born from two carriers of the faulty gene &#119;&#105;&#108;&#108; &#104;&#097;&#118;&#101; cystic fibrosis, &#119;&#105;&#116;&#104; a one in two chance of &#105;&#116; &#098;&#101;&#105;&#110;&#103; a carrier.</p>
<p>Pre-implantation genetic diagnosis involves the testing of embryos, &#099;&#114;&#101;&#097;&#116;&#101;&#100; through IVF treatment, to ensure they are free of genetic conditions, &#098;&#101;&#102;&#111;&#114;&#101; they are implanted.</p>
<p>Dr Mary Porteous, a consultant in clinical genetics &#102;&#111;&#114; NHS Lothian, carried &#111;&#117;&#116; the genetic testing &#102;&#111;&#114; the treatment.</p>
<p>She said: &#8220;&#105;&#116; &#105;&#115; fantastic that we are able to offer &#116;&#104;&#105;&#115; treatment &#102;&#111;&#114; couples &#119;&#104;&#111; are affected by single-gene defects, &#097;&#110;&#100; I &#097;&#109; &#112;&#108;&#101;&#097;&#115;&#101;&#100; that Lee &#097;&#110;&#100; Stephen &#119;&#101;&#114;&#101; the &#102;&#105;&#114;&#115;&#116; couple to benefit.</p>
<p>&#8220;The treatment &#105;&#115; &#111;&#110;&#108;&#121; offered to couples &#119;&#104;&#111; already &#104;&#097;&#118;&#101; &#097;&#110; affected child.&#8221;</p>
<p>Cystic Fibrosis &#105;&#115; one of the UK&#8217;s most common life-threatening inherited diseases, affecting &#109;&#111;&#114;&#101; &#116;&#104;&#097;&#110; 8500 people.</p>
<p>l The condition affects the internal organs, particularly the lungs &#097;&#110;&#100; digestive &#115;&#121;&#115;&#116;&#101;&#109;, by clogging &#116;&#104;&#101;&#109; &#119;&#105;&#116;&#104; thick sticky mucus. &#116;&#104;&#105;&#115; &#109;&#097;&#107;&#101;&#115; &#105;&#116; hard to breathe &#097;&#110;&#100; digest food.</p>
<p>l Symptoms &#099;&#097;&#110; include a troublesome cough, repeated chest infections, prolonged diarrhoea &#097;&#110;&#100; poor weight gain.</p>
<p>l &#109;&#111;&#114;&#101; &#116;&#104;&#097;&#110; two million people in the UK carry the faulty gene that &#099;&#097;&#117;&#115;&#101;&#115; Cystic Fibrosis &#8211; around one in 25 of the population. If two carriers &#104;&#097;&#118;&#101; a child, &#116;&#104;&#101;&#105;&#114; offspring has a one in &#102;&#111;&#117;&#114; chance of having the disease.</p></p>
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