Mycobacteria are abundant in soil and water but are more infamous for the diseases that they can cause. Mycobacterium tuberculosis is perhaps the most well known member of the group and is the bacterium that causes tuberculosis. however, there are other species of mycobacteria, for example Mycobacterium leprae causes leprosy, Mycobacterium bovis causes tuberculosis in cattle, Mycobacterium avium causes disease in immunocompromised people, Mycobacterium bovis Bacille Calmette-Guérin (BCG) is a strain of Mycobacterium bovis used as a vaccine and Mycobacterium smegmatis is a non-pathogenic species used in laboratory research. (Reference: Mycobacterium: Genomics and Molecular Biology ISBN: 978-1-904455-40-0)About one-third of the world’s population is infected with tuberculosis, although the infection is latent because the immune system is usually able to control the Mycobacterium tuberculosis infection. About 10% of infected people become ill with an active form of tuberculosis.Latent tuberculosis infection is when a person is infected with Mycobacterium tuberculosis but does not have symptoms of disease. they are said to be asymptomatic. Active tuberculosis disease is the full-blown disease which, if not treated, will kill half of the patients. one in ten latent infections will progress to active tuberculosis disease. Typical symptoms of an active tuberculosis patient include weakness, fever, chest pain, respiratory insufficiency, fever and cough. Strains of Mycobacterium tuberculosis have become multidrug-resistant making the disease particularly difficult to treat. Treatment includes chemotherapy and a combination of different types of drug. Tuberculosis is spread by infective particles produced through coughing by patients with active tuberculosis. the air-borne particles carrying the bacteria can be inhaled by other people.Leprosy is a disease caused by Mycobacterium leprae, a bacterium related to the species that causes tuberculosis. in medical terms, leprosy is described as a granulomatous disease of the peripheral nerves and mucosa of the upper respiratory tract. Skin lesions are the main visible symptoms. According to the World Health Organization as many as three million people have been disabled due to leprosy. in recent years, leprosy has become a problem in HIV patients using anti-retroviral drugs.different species of Mycobacterium cause tuberculosis, leprosy and other illneses. Mycobacterium is a genus of Actinobacteria, given its own family, the Mycobacteriaceae. Much scientific research is being conducted on these microorganisms. in particular much effort is being directed to the understanding of the genome of Mycobacterium with a view to developing and improving strategies for treatment. (Reference: Mycobacterium: Genomics and Molecular Biology ISBN: 978-1-904455-40-0)

Copyright ©2010. The Associated Press. Produced by NewsOK.com all rights reserved. this material may not be published, broadcast, rewritten, or redistributed.  

The new Multiple Sclerosis Center of Excellence opened Tuesday, built on a concept of combining bedside treatment with laboratory research.

The center is designed to treat thousands of patients in Oklahoma and the region who have symptoms that may include the inability to walk, blindness and paralysis. it is in the Oklahoma Medical Research Foundation’s new seven-floor research tower at 825 NE 13.

The MS center will be headed by Gabriel Pardo, M.D., a neurologist and neuro-ophthalmologist who has specialized in treating MS patients for more than a decade. he said the center will allow an opportunity for top-notch MS scientists and doctors to work together to fight the baffling disease of the central nervous system.

“We meet in the middle. I bring my ideas from the bedside; they bring ideas from the lab side to brainstorm together,” he said.

Patients will be seen in technologically advanced examination rooms.

They will be treated in a specially designed infusion suite, ophthalmological and dental areas, and a physical therapy area with equipment designed just for MS patients.

“This is history-making time in MS. this is when things are happening. We’re understanding a lot of things and coming up with better strategies. what better than to be part of history making?” Pardo said.

Patients also will be able to participate in clinical trials and perhaps have a hand in helping future generations of MS sufferers, Pardo said.

“Multiple sclerosis doesn’t just take a toll on the body, but it drastically impairs a patient’s lifestyle,” said OMRF President Dr. Stephen Prescott.

The disease interrupts the flow of information within the brain, and between the body and brain.

“We’re not only improving our research capabilities with the new center, but by gathering many of the facilities used by MS patients in one place, we hope to make treatment more convenient,” Prescott said.

Experts estimate at least 4,200 Oklahomans have multiple sclerosis.

“As we move toward finding a cure, Oklahomans will now have access to quality, integrated care from this dedicated team of MS specialists,” said Lucy Fraser, development director for the Oklahoma Chapter of the National MS Society.

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Copyright ©2010. the Associated Press. Produced by NewsOK.com all rights reserved. this material may not be published, broadcast, rewritten, or redistributed.  

For the patient with sudden dizziness, inability to walk, slurred speech or the host of other puzzling multiple sclerosis symptoms, a new clinic may offer reason to celebrate.

Officials Tuesday announced the upcoming opening of the OMRF Multiple Sclerosis Center of Excellence to be in the Oklahoma Medical Research Foundation’s new research tower.

“It is a humongous day. It is basically awesome,” said Dr. Gabriel Pardo, a nationally recognized MS researcher and the new center’s director. “What we’re going to be able to achieve here is completely unique.”

Along with diagnosing and treating MS patients, the center’s physician-scientists will conduct clinical and laboratory research on MS. the inflammatory, degenerative disease of the central nervous system affects about 400,000 Americans. about 3,400 Oklahomans are self-identified as having an MS diagnosis, though the number is believed to be at least 4,200.

Pardo said he is excited about the planned March 15 move to the new clinic at OMRF, 825 NE 13.

“Ultimately, we have the goal of curing multiple sclerosis. the complexity of the disease is very, very big. That’s why it will take the approach that we are going to embark on here,” Pardo said.

The new center will allow doctors to treat MS patients at bedside, consult with each other and MS researchers inside the clinic, study how the disease works in patients and ultimately apply what they’ve learned to improve the lives of multiple sclerosis patients everywhere.

The center will feature rooms and equipment dedicated to MS evaluation and treatment. these include high-tech examining rooms, a tower infusion suite, ophthalmological and dental facilities, MS-dedicated physical therapy and computerized testing of the brain.

MS patients also will have the chance to participate in clinical trials so they can use experimental therapies and contribute to the understanding of the disease.

MS patient Lucy Fraser said patients and their loved ones have waited for this and now have reason to celebrate. the Oklahoma City woman was diagnosed 15 years ago, after years of strange symptoms — from leg numbness to arm numbness to vertigo — coming and going during the course of the disease.

She was finally diagnosed and eventually found her way to Pardo’s offices at the Neuroscience Institute at Mercy, where he will serve as the medical director of the MS Center of Oklahoma until he moves to OMRF. Fraser, who has since taken a job with the National MS Society, said she was initially hesitant to become one of his patients because he had 800 patients at the time, though it was a fraction of the 2,000 he now sees.

Pardo, an internationally recognized neurologist and neuro-ophthalmologist, impressed her so much she choked up in telling it. she overheard him telling a doctor, “When I was with the university (U.M. Nueva Granada, Bogota), I fell in love with MS.”

Along with Pardo, Dr. Farhat Husain also will join the center’s medical staff. Husain is a neurologist who currently treats more than 300 MS patients through Southwest Neurological Associates in Oklahoma City.

Fraser said the potential is significant because the doctors, scientists, physician assistants, physical therapists and other MS personnel are within arm’s reach of patients and the research laboratories.

“We really do feel like there is a cure out there. It is so exciting to know that now that OMRF is joining the fight, it’s going to move faster,” Fraser said.

Edmond MS patient Lori Evans said it’s amazing how important the new clinic is to MS patients.

“That is unbelievable. all these clinical trials will hopefully lead to a cure and a way to regenerate the nerves of people like myself,” she said.

After the March move-in, the OMRF Multiple Sclerosis center will ultimately take up three floors in its seven-floor research tower home. Supported by private donors and grants from the state and the federal government, the tower is believed to be the first medical facility anywhere that will harness the wind to help power its labs.

The tower is the biggest expansion project in the 64-year history of Oklahoma Medical Research Foundation, increasing the 50 principal investigators and roughly 500 employees to 80 investigators and 800 employees.

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