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	<title>Symptom Advice .com &#187; menopausal symptoms</title>
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		<title>Menopause Treatment Part 2: My Escape from Hormone Hell</title>
		<link>http://symptomadvice.com/menopause-treatment-part-2-my-escape-from-hormone-hell/</link>
		<comments>http://symptomadvice.com/menopause-treatment-part-2-my-escape-from-hormone-hell/#comments</comments>
		<pubDate>Thu, 17 Mar 2011 12:17:06 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[hormone symptoms]]></category>
		<category><![CDATA[hormone pills]]></category>
		<category><![CDATA[hot flashes]]></category>
		<category><![CDATA[menopausal symptoms]]></category>
		<category><![CDATA[menopause]]></category>
		<category><![CDATA[rocking chair]]></category>
		<category><![CDATA[voices]]></category>

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		<description><![CDATA[Menopause Treatment Part 1: Forget the Damn Rocking Chair! The Day &#109;&#121; Doctor &#097;&#110;&#100; I &#103;&#111;&#116; &#105;&#110;&#116;&#111; A Screaming Match OK, I&#8217;m exaggerating. &#119;&#101; weren&#8217;t really screaming &#8211; &#106;&#117;&#115;&#116; &#8216;raising our voices&#8217; a bit. I &#119;&#101;&#110;&#116; to &#104;&#105;&#109; to talk about &#109;&#121; menopausal symptoms, &#097;&#110;&#100; I have to admit &#116;&#104;&#101;&#121; weren&#8217;t &#110;&#101;&#097;&#114;&#108;&#121; &#097;&#115; severe &#097;&#115; [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><strong><u>Menopause Treatment Part 1: Forget the Damn Rocking Chair! </u></strong></p>
<p><strong>The Day &#109;&#121; Doctor &#097;&#110;&#100; I &#103;&#111;&#116; &#105;&#110;&#116;&#111; A Screaming Match</strong></p>
<p>OK, I&#8217;m exaggerating. &#119;&#101; weren&#8217;t really screaming &ndash; &#106;&#117;&#115;&#116; &#8216;raising our voices&#8217; a bit. I &#119;&#101;&#110;&#116; to &#104;&#105;&#109; to talk about &#109;&#121; menopausal symptoms, &#097;&#110;&#100; I have to admit &#116;&#104;&#101;&#121; weren&#8217;t &#110;&#101;&#097;&#114;&#108;&#121; &#097;&#115; severe &#097;&#115; some &#111;&#102; &#109;&#121; women friends. Basically, I had two:</p>
<p><img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> Weight gain &ndash; a LOT &#111;&#102; weight <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> Hot flashes</p>
<p>When I tried to talk &#119;&#105;&#116;&#104; &#109;&#121; doctor he didn&#8217;t listen very long &hellip; then he reached &#102;&#111;&#114; his prescription pad. He &#101;&#120;&#112;&#108;&#097;&#105;&#110;&#101;&#100; &#116;&#104;&#097;&#116; I &#115;&#104;&#111;&#117;&#108;&#100; take hormone pills &#102;&#111;&#114; an extended time, the length &#111;&#102; which &#119;&#097;&#115; undetermined.</p>
<p>When I asked &#104;&#105;&#109; if there weren&#8217;t other alternatives he impatiently cut &#109;&#101; &#111;&#102;&#102;. I asked &ldquo;awkward&rdquo; &#113;&#117;&#101;&#115;&#116;&#105;&#111;&#110;&#115; &#108;&#105;&#107;&#101;: &#104;&#111;&#119; women survived menopause &#102;&#111;&#114; thousands &#111;&#102; years &#119;&#105;&#116;&#104;&#111;&#117;&#116; hormones? the &#115;&#105;&#100;&#101; effects &#111;&#102; hormones? what these hormones &#119;&#111;&#117;&#108;&#100; &#100;&#111; to &#102;&#111;&#114; &#109;&#121; menopausal symptoms?</p>
<p>His annoyance grew to the point &#111;&#102; an argument between &#117;&#115; &#116;&#104;&#097;&#116; grew louder &#097;&#110;&#100; louder.</p>
<p>I left &#097;&#110;&#100; never &#119;&#101;&#110;&#116; &#098;&#097;&#099;&#107;. &#097;&#110;&#100; I started searching &#102;&#111;&#114; &#097;&#110;&#115;&#119;&#101;&#114;&#115; &#111;&#102; &#109;&#121; &#111;&#119;&#110;, &#097;&#110;&#115;&#119;&#101;&#114;&#115; &#116;&#104;&#097;&#116; did &#110;&#111;&#116; include adding artificial hormones to &#109;&#121; body.</p>
<p><img src="content.blissplan.com/img/naturalremediesline.jpg" width="554" height="4"></p>
<p><strong>Meet Dr. Holly Lucille &#8230;</strong></p>
<p><img src="content.blissplan.com/img/naturalremediesline.jpg" width="554" height="4"> </p>
<p>Then I &ldquo;met&rdquo; Dr. Holly Lucille. She is a &ldquo;Beverly Hills&rdquo; doctor who &#097;&#108;&#115;&#111; entered Hormone Hell. She says, &ldquo;I had to hit 175 pounds &#097;&#110;&#100; watch &#109;&#121; &#111;&#119;&#110; energy &#097;&#110;&#100; sex drive hit the wall &#098;&#101;&#102;&#111;&#114;&#101; I did &#115;&#111;&#109;&#101;&#116;&#104;&#105;&#110;&#103; about &#105;&#116;.&rdquo;</p>
<p>My &#113;&#117;&#101;&#115;&#116;&#105;&#111;&#110;: <strong><u>ONLY 175</u></strong>? I outdid &#121;&#111;&#117; (past tense!) Dr. Holly!</p>
<p><img src="content.blissplan.com/img/misc/drhollylucille.jpg" width="200" height="250"></p>
<p><strong>About Dr. Holly Lucille, N.D.,R.N. &amp; Author</strong></p>
<p> Dr. Holly Lucille is a licensed Naturopathic Physician &#097;&#110;&#100; past president &#111;&#102; the California Naturopathic Doctor&#8217;s Association. She &#104;&#097;&#115; worked &#119;&#105;&#116;&#104; the LA Free Clinic providing health education, promotion &#097;&#110;&#100; prevention in the public health system &#097;&#110;&#100; &#108;&#097;&#115;&#116; year &#119;&#097;&#115; awarded the &quot;SCNM Legacy Award&quot; &#102;&#111;&#114; her &quot;contribution to the advancement &#097;&#110;&#100; development &#111;&#102; the field &#111;&#102; Naturopathic Medicine&quot;. </p>
<p> Dr. Lucille is &#111;&#110; the clinical staff &#111;&#102; Renaissance Malibu, an addiction &#097;&#110;&#100; recovery center, &#119;&#104;&#101;&#114;&#101; she applies the principles &#111;&#102; Naturopathic Medicine to aid people in recovery. She is a member &#111;&#102; the Scientific Advisory Board &#111;&#102; &#098;&#111;&#116;&#104; Enzymatic Therapy &#097;&#110;&#100; Integrative Therapeutics, Inc. &#097;&#110;&#100; &#104;&#097;&#115; a private practice in Los Angeles.</p>
<p> Dr. Lucille lectures throughout the nation &#097;&#110;&#100; &#104;&#097;&#115; &#098;&#101;&#101;&#110; featured &#111;&#110; Lifetime Television &#102;&#111;&#114; Women &#097;&#110;&#100; the Discovery Health Channel &#097;&#115; well, &#098;&#101;&#101;&#110; a guest &#111;&#110; a number &#111;&#102; radio &#115;&#104;&#111;&#119; speaking &#111;&#110; naturopathic medicine. She &#104;&#097;&#115; recently joined forces &#119;&#105;&#116;&#104; Jon Benson, the author &#111;&#102; Fit Over &#102;&#111;&#114;&#116;&#121; to develop &quot;Naturopause&quot;. </p>
<p>What Dr. Holly said made total sense to &#109;&#101;.</p>
<p>The Solution is to <u>restore</u> your hormones, &#110;&#111;&#116; &ldquo;replace&rdquo; them.</p>
<p><img src="content.blissplan.com/img/naturalremediesline.jpg" width="554" height="4"></p>
<p><strong>Band Aid Menopause Drugs</strong></p>
<p><img src="content.blissplan.com/img/naturalremediesline.jpg" width="554" height="4"> </p>
<p>Dr. Holly calls the &#118;&#097;&#114;&#105;&#111;&#117;&#115; drugs prescribed &#102;&#111;&#114; menopause &ldquo;band aid drugs&rdquo; &#098;&#101;&#099;&#097;&#117;&#115;&#101; &#116;&#104;&#101;&#121; <strong><u>treat symptoms &#098;&#117;&#116; &#116;&#104;&#101;&#121; don&#8217;t really take care &#111;&#102; the cause</u></strong>!</p>
<p>It took a decade &#111;&#102; research, &#097;&#110;&#100; &#111;&#110;&#101; year &#111;&#102; working &#119;&#105;&#116;&#104; fellow health professional Jon Benson, to develop a <u><strong>100% GUARANTEED</strong></u><u><strong> </strong></u>solution to &#116;&#104;&#105;&#115; problem &mdash; &#111;&#110;&#101; &#116;&#104;&#097;&#116; works to restore hormones, boost them higher &#117;&#115;&#105;&#110;&#103; <strong>natural methods</strong>, &#097;&#110;&#100;, if &#121;&#111;&#117; are &#111;&#110; HRT, supplement your life &#119;&#105;&#116;&#104; specific nutrients to help keep &#121;&#111;&#117; safe.</p>
<p>Here are some &#111;&#102; the valuable clues I gained from Dr. Holly:</p>
<p> <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> <strong>The real, absolute, without-a-doubt &#099;&#097;&#117;&#115;&#101; &#111;&#102; &#110;&#101;&#097;&#114;&#108;&#121; &#097;&#108;&#108; your symptoms&mdash;&#097;&#110;&#100; &#104;&#111;&#119; to get rid &#111;&#102; them, &#109;&#097;&#107;&#101; &#121;&#111;&#117; feel &#098;&#101;&#116;&#116;&#101;&#114;, &#097;&#110;&#100; radically boost your mental, emotional, &#097;&#110;&#100; physical health&mdash;&#097;&#108;&#108; at the &#115;&#097;&#109;&#101; time</strong> <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> &#119;&#104;&#121; 95% &#111;&#102; doctors never treat &#116;&#104;&#105;&#115; hormonally-based cause&mdash;&#097;&#110;&#100; &#119;&#104;&#121; &#121;&#111;&#117; still feel bad &#097;&#110;&#100; have down-right dangerous &#115;&#105;&#100;&#101; effects from &#097;&#108;&#108; the drugs &#097;&#110;&#100; &ldquo;&#104;&#097;&#112;&#112;&#121; pills&rdquo; &#116;&#104;&#101;&#121; keep giving &#121;&#111;&#117; <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> <strong>A top-to-bottom, &ldquo;treat the cause&rdquo; Solution that&#8217;s proven, tested in clinics &#097;&#110;&#100; the real world, &#097;&#110;&#100; based in fact &#097;&#110;&#100; medicine that&#8217;s &#098;&#101;&#101;&#110; successful &#102;&#111;&#114; thousands &#111;&#102; years</strong> <img src="content.blissplan.com/img/healthylifestyleseal.jpg" width="125" height="125" align="right"><img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> Throw away &#116;&#104;&#111;&#115;&#101; expensive &#097;&#110;&#100; dangerous drugs in favor &#111;&#102; &#108;&#101;&#115;&#115; expensive natural options &#8230; or, if &#121;&#111;&#117; &#117;&#115;&#101; HRT, discover the 5 &#116;&#104;&#105;&#110;&#103;&#115; &#121;&#111;&#117; absolutely &#109;&#117;&#115;&#116; know to help ensure your safety <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> <strong>Remember what it&#8217;s &#108;&#105;&#107;&#101; to be sexually &#111;&#110; fire &#105;&#110;&#115;&#116;&#101;&#097;&#100; &#111;&#102; &ldquo;burning up&rdquo; from hot flashes &#097;&#110;&#100; night sweats</strong> <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> Put an end to the psychological damage &#121;&#111;&#117; are experiencing &#098;&#121; feeling &ldquo;old&rdquo;, &ldquo;&#110;&#111;&#116; sexy&rdquo;, or &ldquo;used up&rdquo; &mdash; &#097;&#110;&#100; &#104;&#111;&#119; to &#117;&#115;&#101; &#116;&#104;&#105;&#115; time to achieve greater respect, &#108;&#111;&#118;&#101;, nurturing, &#097;&#110;&#100; honor <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> <strong>Eat simply, deliciously &#097;&#110;&#100; successfully &#8230; &#097;&#110;&#100; uncover the hidden foods &#116;&#104;&#097;&#116; help &#099;&#097;&#117;&#115;&#101; your problems</strong> <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> The &ldquo;mother &#111;&#102; &#097;&#108;&#108; hormones&rdquo; &mdash; &#097;&#110;&#100; &#119;&#104;&#121; your doctor may be killing &#121;&#111;&#117; &#098;&#121; lowering &#105;&#116; <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> <strong>What is really causing your weight gain, &#097;&#110;&#100; &#104;&#111;&#119; &#121;&#111;&#117; can shed the pounds naturally &#097;&#110;&#100; permanently </strong> <img src="content.blissplan.com/img/greenarrow2.jpg" width="22" height="20"> The &ldquo;smear campaigns&rdquo; &#116;&#104;&#097;&#116; drive &#121;&#111;&#117; away from alternatives &#116;&#104;&#097;&#116; are cheaper, safer, &#097;&#110;&#100; &#109;&#111;&#114;&#101; effective</p>
<p><img src="content.blissplan.com/img/naturalremediesline.jpg" width="554" height="4"></p>
<p><strong>NaturaPause</strong></p>
<p><img src="content.blissplan.com/img/naturalremediesline.jpg" width="554" height="4"></p>
<p>Dr. Holly&#8217;s program is called <u><strong>NaturaPause</strong></u> &#097;&#110;&#100; includes:</p>
<p><strong> <img src="content.blissplan.com/img/misc/naturapause.jpg" width="194" height="230" border="0" align="left"><img src="content.blissplan.com/img/checkmark/greencheckmark2.jpg" width="24" height="22"> 6 CDs <img src="content.blissplan.com/img/checkmark/greencheckmark2.jpg" width="24" height="22"> The NaturaPause Study Guide <img src="content.blissplan.com/img/checkmark/greencheckmark2.jpg" width="24" height="22"> Audio Transcripts <img src="content.blissplan.com/img/checkmark/greencheckmark2.jpg" width="24" height="22">Holly&#8217;s breakthrough book &#099;&#114;&#101;&#097;&#116;&#105;&#110;&#103; &#097;&#110;&#100; Maintaining Balance: A Guide To Safe, Natural Hormone Health! </strong></p></p>
]]></content:encoded>
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		<item>
		<title>Study: Hot flashes can be good</title>
		<link>http://symptomadvice.com/study-hot-flashes-can-be-good/</link>
		<comments>http://symptomadvice.com/study-hot-flashes-can-be-good/#comments</comments>
		<pubDate>Mon, 07 Mar 2011 08:34:11 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[blood symptoms]]></category>
		<category><![CDATA[co author]]></category>
		<category><![CDATA[government study]]></category>
		<category><![CDATA[hot flashes]]></category>
		<category><![CDATA[menopausal symptoms]]></category>
		<category><![CDATA[northwestern university]]></category>

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		<description><![CDATA[CHICAGO – Hot flashes that bedevil many women &#105;&#110; menopause might &#097;&#099;&#116;&#117;&#097;&#108;&#108;&#121; be &#097; good &#116;&#104;&#105;&#110;&#103;, depending &#111;&#110; when they strike, &#097;&#099;&#099;&#111;&#114;&#100;&#105;&#110;&#103; &#116;&#111; &#110;&#101;&#119; data from &#097; long-running government study. Women &#119;&#104;&#111; had hot flashes &#097;&#116; the start of menopause but not &#108;&#097;&#116;&#101;&#114; &#115;&#101;&#101;&#109;&#101;&#100; &#116;&#111; &#104;&#097;&#118;&#101; &#097; lower risk &#102;&#111;&#114; heart attack and death than [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/03/1299486851-75.gif" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" />
<p>CHICAGO – Hot flashes that bedevil many women &#105;&#110; menopause might &#097;&#099;&#116;&#117;&#097;&#108;&#108;&#121; be &#097; good &#116;&#104;&#105;&#110;&#103;, depending &#111;&#110; when they strike, &#097;&#099;&#099;&#111;&#114;&#100;&#105;&#110;&#103; &#116;&#111; &#110;&#101;&#119; data from &#097; long-running government study.</p>
<p>Women &#119;&#104;&#111; had hot flashes &#097;&#116; the start of menopause but not &#108;&#097;&#116;&#101;&#114; &#115;&#101;&#101;&#109;&#101;&#100; &#116;&#111; &#104;&#097;&#118;&#101; &#097; lower risk &#102;&#111;&#114; heart attack and death than women &#119;&#104;&#111; never had hot flashes &#111;&#114; &#116;&#104;&#111;&#115;&#101; &#119;&#104;&#111;&#115;&#101; symptoms persisted long after menopause began.</p>
<p>The research involved &#109;&#111;&#114;&#101; than 60,000 women followed &#102;&#111;&#114; &#097;&#110; average of almost 10 years. It’s the first &#116;&#111; examine timing of menopausal symptoms and subsequent risks &#102;&#111;&#114; heart problems and deaths, said co-author Dr. JoAnn Manson, chief of preventive medicine &#097;&#116; Harvard’s Brigham and Women’s Hospital.</p>
<p>Recent studies linked hot flashes with higher blood pressure and cholesterol levels, &#119;&#104;&#105;&#099;&#104; &#099;&#111;&#117;&#108;&#100; suggest &#097; higher risk &#102;&#111;&#114; heart problems, but the &#110;&#101;&#119; research offers &#097; &#109;&#111;&#114;&#101; detailed &#108;&#111;&#111;&#107;, Manson said.</p>
<p>Lead author Dr. Emily Szmuilowicz, &#097;&#110; endocrinologist with Northwestern University’s medical school, said the results &#115;&#104;&#111;&#117;&#108;&#100; reassure millions of women &#119;&#104;&#111; experience hot flashes &#111;&#114; night sweats, &#119;&#104;&#105;&#099;&#104; are essentially hot flashes that &#099;&#097;&#110; be bothersome enough &#116;&#111; awaken women.</p>
<p>The results suggest “there may be &#097; positive side” &#116;&#111; having these annoying symptoms, Szmuilowicz said.</p>
<p>The study was released &#105;&#110; the journal Menopause.</p>
<p>Dr. Elsa-Grace Giardina, &#097; Columbia University specialist &#105;&#110; women’s heart disease &#119;&#104;&#111; was not involved &#105;&#110; the study, said the research has &#115;&#101;&#118;&#101;&#114;&#097;&#108; limitations and that &#109;&#111;&#114;&#101; rigorous study &#105;&#115; needed &#116;&#111; prove the results.</p>
<p>Few women developed hot flashes long after menopause began, and &#102;&#111;&#114; &#097;&#116; least some, previous use of hormone pills may &#104;&#097;&#118;&#101; increased &#116;&#104;&#101;&#105;&#114; risks &#102;&#111;&#114; heart problems, Giardina said.</p>
<p>But &#109;&#111;&#114;&#101; than one third of the women with late-onset symptoms never &#117;&#115;&#101;&#100; hormones, and Szmuilowicz said the researchers took &#112;&#097;&#115;&#116; hormone use into consideration and still &#102;&#111;&#117;&#110;&#100; timing of symptoms played &#097; role.</p>
<p>Menopause occurs when women stop having periods and estrogen levels dwindle. Most women experience symptoms including hot flashes that &#099;&#097;&#110; &#108;&#097;&#115;&#116; &#102;&#111;&#114; &#115;&#101;&#118;&#101;&#114;&#097;&#108; years. But they don’t &#117;&#115;&#117;&#097;&#108;&#108;&#121; persist indefinitely &#111;&#114; &#098;&#101;&#103;&#105;&#110; long after the beginning of menopause.</p>
<p>Hot flashes aren’t &#119;&#101;&#108;&#108; studied but are thought &#116;&#111; result from blood vessels dilating &#105;&#110; response &#116;&#111; the normal hormone fluctuations of menopause, Manson said. If they occur long after menopause &#098;&#101;&#103;&#105;&#110;&#115;, it &#099;&#111;&#117;&#108;&#100; signal &#097; blood vessel abnormality that &#099;&#111;&#117;&#108;&#100; &#097;&#108;&#115;&#111; affect the heart, she said.</p>
<p>The research involved 60,027 women from the ongoing Women’s Health Initiative observational study, examining disease risk factors and health outcomes and funded by the National Institutes of Health.</p>
<p>Women were &#105;&#110; &#116;&#104;&#101;&#105;&#114; early 60s &#111;&#110; average, &#097;&#098;&#111;&#117;&#116; 14 years &#112;&#097;&#115;&#116; the start of menopause, when they &#097;&#110;&#115;&#119;&#101;&#114;&#101;&#100; questionnaires &#097;&#098;&#111;&#117;&#116; &#116;&#104;&#101;&#105;&#114; health, education history, and symptoms including hot flashes and night sweats. Cardiovascular problems and deaths were tracked &#100;&#117;&#114;&#105;&#110;&#103; almost 10 years of follow-up.</p>
<p>More than one third, &#111;&#114; almost 25,000 women, had early symptoms – hot flashes &#097;&#116; the onset of menopause that had stopped &#098;&#101;&#102;&#111;&#114;&#101; they enrolled. Just 1,391 had late symptoms – hot flashes &#097;&#116; enrollment but not &#097;&#116; the start of menopause.</p>
<p>About 2.5 percent of women with early symptoms had heart attacks, compared with 3.4 percent of women with &#110;&#111; symptoms and 5.5 percent of &#116;&#104;&#111;&#115;&#101; with late symptoms. &#097;&#108;&#115;&#111;, &#097;&#098;&#111;&#117;&#116; 6 percent of the early-symptom women died, versus 11 percent of the late-symptom group and 8 percent of the symptomless women. Women &#119;&#104;&#111; had persistent hot flashes &#116;&#104;&#114;&#111;&#117;&#103;&#104;&#111;&#117;&#116; menopause had risks similar &#116;&#111; &#116;&#104;&#111;&#115;&#101; &#119;&#105;&#116;&#104;&#111;&#117;&#116; symptoms.</p>
<p>Giardina noted that high blood pressure, high cholesterol, diabetes and obesity – &#119;&#104;&#105;&#099;&#104; all &#099;&#097;&#110; contribute &#116;&#111; heart problems – were &#109;&#111;&#114;&#101; common among the late-symptom women.</p>
<p>But the researchers said they accounted &#102;&#111;&#114; that and still &#102;&#111;&#117;&#110;&#100; that timing of menopause symptoms played &#097; role &#105;&#110; &#108;&#097;&#116;&#101;&#114; heart attacks and deaths.</p>
<p><strong>Tags:</strong> life,&nbsp;health </p></p>
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		<title>Ausio Pharmaceutical’s ER? Agonist AUS-131 is Well Tolerated in First Human Clinical Trials</title>
		<link>http://symptomadvice.com/ausio-pharmaceutical%e2%80%99s-er%ce%b2-agonist-aus-131-is-well-tolerated-in-first-human-clinical-trials/</link>
		<comments>http://symptomadvice.com/ausio-pharmaceutical%e2%80%99s-er%ce%b2-agonist-aus-131-is-well-tolerated-in-first-human-clinical-trials/#comments</comments>
		<pubDate>Tue, 08 Feb 2011 22:17:14 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[prostate symptoms]]></category>
		<category><![CDATA[benign prostatic hyperplasia]]></category>
		<category><![CDATA[menopausal symptoms]]></category>
		<category><![CDATA[phase 1 clinical trials]]></category>
		<category><![CDATA[phase 2]]></category>
		<category><![CDATA[vasomotor symptoms]]></category>
		<category><![CDATA[volunteers]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/ausio-pharmaceutical%e2%80%99s-er%ce%b2-agonist-aus-131-is-well-tolerated-in-first-human-clinical-trials/</guid>
		<description><![CDATA[02.07.2011&#8211; February 7, 2011 (Cincinnati, Ohio) — Results &#111;&#102; &#116;&#119;&#111; Phase 1 clinical trials &#111;&#102; S-equol (AUS-131) &#119;&#101;&#114;&#101; published in the February issue &#111;&#102; Menopause: The Journal &#111;&#102; the North American Menopause Society. &#116;&#104;&#105;&#115; first-in-class, nonsteroidal, nonhormonal estrogen receptor ? (ER?) agonist offers a potentially safer alternative to estrogen &#102;&#111;&#114; the treatment &#111;&#102; menopausal symptoms. [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/02/1297203434-90.jpg%3Fw%3D527%26h%3D576%26h%3D576" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" />
<p> 02.07.2011&ndash; February 7, 2011 (Cincinnati, Ohio) — Results &#111;&#102; &#116;&#119;&#111; Phase 1 clinical trials &#111;&#102; S-equol (AUS-131) &#119;&#101;&#114;&#101; published in the February issue &#111;&#102; Menopause: The Journal &#111;&#102; the North American Menopause Society. &#116;&#104;&#105;&#115; first-in-class, nonsteroidal, nonhormonal estrogen receptor ? (ER?) agonist offers a potentially safer alternative to estrogen &#102;&#111;&#114; the treatment &#111;&#102; menopausal symptoms. As &#112;&#097;&#114;&#116; &#111;&#102; a drug development program, &#116;&#104;&#101;&#115;&#101; studies &#119;&#101;&#114;&#101; the &#102;&#105;&#114;&#115;&#116; to investigate AUS-131 in humans. Results demonstrated a favorable safety &#097;&#110;&#100; pharmacokinetic profile &#102;&#111;&#114; AUS-131, &#097;&#110;&#100; &#104;&#097;&#118;&#101; allowed the company to proceed to Phase 2 clinical trials, &#119;&#104;&#105;&#099;&#104; &#119;&#105;&#108;&#108; be completed in Q3 2011. &#116;&#104;&#101;&#115;&#101; studies evaluated the pharmacokinetics &#097;&#110;&#100; tolerability &#111;&#102; single &#097;&#110;&#100; multiple oral doses &#111;&#102; AUS-131 in healthy volunteers. &#116;&#104;&#101;&#115;&#101; studies also established the doses &#102;&#111;&#114; proof-of-concept Phase 2 studies investigating AUS-131 as a treatment &#102;&#111;&#114; postmenopausal women with vasomotor symptoms (VMS), commonly referred to as hot flashes. Results also support Ausio’s development &#111;&#102; AUS-131 as a treatment option to inhibit prostate cell growth in men with benign prostatic hyperplasia (BPH). The full paper is &#097;&#118;&#097;&#105;&#108;&#097;&#098;&#108;&#101; at: journals.lww.com/menopausejournal/Abstract/2011/02000/Single_dose_and_steady_statepharmacokinetic.15.aspx “One &#111;&#102; the compelling reasons &#102;&#111;&#114; developing S-equol as a pharmaceutical product is &#116;&#104;&#097;&#116; women &#097;&#114;&#101; reluctant to &#116;&#097;&#107;&#101; estrogens &#102;&#111;&#114; their menopausal symptoms” said Richard Jackson, PhD, Ausio Pharmaceuticals, LLC, President &#097;&#110;&#100; CEO, &#097;&#110;&#100; the study’s lead author. “Based &#111;&#110; the Phase 1 studies, AUS-131 offers an oral medication &#116;&#104;&#097;&#116; safely delivers therapeutic levels &#111;&#102; S-equol, &#119;&#104;&#105;&#099;&#104; &#109;&#097;&#121; benefit patients with a variety &#111;&#102; diseases &#097;&#110;&#100; conditions.” History &#111;&#102; Treatment &#111;&#102; Menopausal Symptoms &#097;&#110;&#100; Significance &#111;&#102; S-Equol &#119;&#104;&#101;&#114;&#101;&#097;&#115; hormone therapy (HT) &#104;&#097;&#115; been the therapy &#111;&#102; choice &#102;&#111;&#114; the management &#111;&#102; menopausal symptoms in women, the Women’s Health Initiative &#104;&#097;&#115; shown &#116;&#104;&#097;&#116; HT &#104;&#097;&#115; been &#097;&#115;&#115;&#111;&#099;&#105;&#097;&#116;&#101;&#100; with increased risk &#111;&#102; invasive breast cancer, coronary heart disease, stroke, &#097;&#110;&#100; deep vein thrombosis. &#116;&#104;&#105;&#115; increased risk is &#097;&#115;&#115;&#111;&#099;&#105;&#097;&#116;&#101;&#100; with the abundance &#097;&#110;&#100; prominent role &#111;&#102; the estrogen receptor ? (ER?) in the breast, uterus, &#097;&#110;&#100; endothelium in the cardiovascular system. Alternative treatments &#102;&#111;&#114; VMS &#104;&#097;&#118;&#101; included serotonin, norepinephrine, mixed reuptake inhibitors, &#097;&#110;&#100; botanicals such as soy products &#097;&#110;&#100; black cohosh, &#098;&#117;&#116; &#116;&#104;&#101;&#115;&#101; treatments &#104;&#097;&#118;&#101; &#098;&#111;&#116;&#104; efficacy &#097;&#110;&#100; safety issues. &#098;&#101;&#121;&#111;&#110;&#100; botanicals, purified, nonsteroidal isoflavones &#102;&#111;&#117;&#110;&#100; in soy—genistein, daidzein, &#097;&#110;&#100; glycitien—have been studied &#102;&#111;&#114; the treatment &#111;&#102; chronic diseases in the aging population, including, &#097;&#109;&#111;&#110;&#103; others, VMS in postmenopausal women, with limited success. Daidzein is &#102;&#117;&#114;&#116;&#104;&#101;&#114; biotransformed to the isoflavan S-equol by the intestinal bacteria flora &#111;&#102; certain individuals, particularly Asians. Published reports show &#116;&#104;&#097;&#116; patients &#119;&#104;&#111; demonstrate the health benefits &#111;&#102; soy &#097;&#114;&#101; &#116;&#104;&#111;&#115;&#101; &#119;&#104;&#111; &#097;&#114;&#101; equol producers. Cincinnati-based Ausio Pharmaceuticals, LLC &#104;&#097;&#115; developed a patented chemical process &#102;&#111;&#114; the synthesis &#111;&#102; S-equol &#116;&#104;&#097;&#116; allows &#102;&#111;&#114; large-scale production &#111;&#102; pure GMP-quality S-equol to conduct clinical trials. About the Studies &#116;&#119;&#111; randomized, double-blind, placebo-controlled clinical trials &#119;&#101;&#114;&#101; performed in healthy volunteers: a single-rising dose study in 61 participants &#097;&#110;&#100; a 14-day repeat-dose study in 40 participants. Safety, tolerability, &#097;&#110;&#100; pharmacokinetics &#111;&#102; AUS-131 &#119;&#101;&#114;&#101; assessed in &#098;&#111;&#116;&#104; men &#097;&#110;&#100; women. AUS-131 &#119;&#097;&#115; well-tolerated by &#097;&#108;&#108; participants with no significant drug-related adverse events at doses several-fold higher &#116;&#104;&#097;&#110; the expected therapeutic range. Food decreased maximal plasma concentration &#098;&#117;&#116; &#100;&#105;&#100; &#110;&#111;&#116; significantly affect &#111;&#118;&#101;&#114;&#097;&#108;&#108; exposure to the drug. AUS-131 &#119;&#097;&#115; readily absorbed with a steady-state level &#111;&#102; S-equol achieved after the &#102;&#105;&#114;&#115;&#116; day &#111;&#102; twice-daily dosing. The pharmacokinetics &#111;&#102; the drug &#119;&#101;&#114;&#101; linear with dose &#097;&#110;&#100; showed &#116;&#104;&#097;&#116; the drug &#119;&#097;&#115; readily cleared from the body. Subjects receiving the lower doses &#111;&#102; AUS-131 achieved plasma levels &#111;&#102; S-equol equivalent to &#116;&#104;&#111;&#115;&#101; &#116;&#104;&#097;&#116; researchers &#104;&#097;&#118;&#101; &#097;&#115;&#115;&#111;&#099;&#105;&#097;&#116;&#101;&#100; with the health benefits &#111;&#102; ingestion &#111;&#102; soy. &#116;&#104;&#101;&#115;&#101; studies in healthy participants also &#112;&#114;&#111;&#118;&#105;&#100;&#101;&#100; the &#102;&#105;&#114;&#115;&#116; report &#111;&#102; plasma &#097;&#110;&#100; urine levels &#111;&#102; unconjugated S-equol after oral dosing using a &#114;&#101;&#099;&#101;&#110;&#116;&#108;&#121; published highly sensitive method. Results from Phase 1 studies &#112;&#114;&#111;&#118;&#105;&#100;&#101;&#100; dosing information &#102;&#111;&#114; the ongoing international, multicenter Phase 2a efficacy trials in patients with VMS &#097;&#110;&#100; BPH. About AUS-131 AUS-131 is a first-in-class, nonsteroidal, nonhormonal, selective ER? agonist &#116;&#104;&#097;&#116; &#104;&#097;&#115; the potential to provide the therapeutic benefits &#116;&#104;&#097;&#116; researchers &#104;&#097;&#118;&#101; attributed to soy ingestion. Importantly, results to date show &#116;&#104;&#097;&#116; the compound &#104;&#097;&#115; an &#101;&#120;&#099;&#101;&#108;&#108;&#101;&#110;&#116; safety profile. AUS-131 is pure, synthetic S-equol, &#119;&#104;&#105;&#099;&#104; is a soy isoflavone &#116;&#104;&#097;&#116; is naturally produced in a small percent &#111;&#102; individuals in the US after ingestion &#111;&#102; soy. &#116;&#104;&#105;&#115; molecule is being evaluated &#102;&#111;&#114; a wide range &#111;&#102; indications, including menopausal symptoms, BPH, osteoporosis, &#097;&#110;&#100; topical applications. About Vasomotor Symptoms In the US, there &#097;&#114;&#101; more &#116;&#104;&#097;&#110; 40 million postmenopausal women. More &#116;&#104;&#097;&#110; 70% &#111;&#102; &#116;&#104;&#101;&#115;&#101; women experience hot flashes. The major products &#097;&#118;&#097;&#105;&#108;&#097;&#098;&#108;&#101; to treat &#116;&#104;&#101;&#115;&#101; symptoms &#097;&#114;&#101; estrogens, &#119;&#104;&#105;&#099;&#104; &#104;&#097;&#118;&#101; current US sales &#111;&#102; $1.8 billion, &#100;&#101;&#115;&#112;&#105;&#116;&#101; the risks &#097;&#115;&#115;&#111;&#099;&#105;&#097;&#116;&#101;&#100; with their use. The results &#111;&#102; the Women’s Health Initiative study showing increased risk &#111;&#102; breast cancer, cardiovascular events, stroke, &#097;&#110;&#100; venous thrombosis with long-term estrogen-progestin therapy &#104;&#097;&#118;&#101; dramatically decreased the use &#111;&#102; estrogen therapy &#097;&#110;&#100; increased the market opportunity &#102;&#111;&#114; new VMS therapy with an ER? agonist, such as the S-equol product, AUS-131. About Ausio Pharmaceuticals Ausio Pharmaceuticals, LLC, is a private biotechnology development company focused &#111;&#110; the advancement &#111;&#102; safe &#097;&#110;&#100; effective medicines &#102;&#111;&#114; the aging population. Ausio &#119;&#097;&#115; founded in 2006 by Richard Jackson, PhD based &#111;&#110; technologies licensed from the Australian Health &#097;&#110;&#100; Nutrition Association Ltd, NSW, Australia, &#097;&#110;&#100; Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio. The company &#104;&#097;&#115; garnered a strong patent position &#102;&#111;&#114; its lead compound, AUS 131. &#105;&#116; &#104;&#097;&#115; rapidly developed AUS-131 by working with &#101;&#120;&#099;&#101;&#108;&#108;&#101;&#110;&#116; service providers. Ausio’s strategic goal is to collaborate with international pharmaceutical partners &#102;&#111;&#114; AUS-131 in the US &#097;&#110;&#100; other markets worldwide. &#102;&#111;&#114; &#102;&#117;&#114;&#116;&#104;&#101;&#114; information &#111;&#110; Ausio, &#112;&#108;&#101;&#097;&#115;&#101; visit the company’s website at ausiopharma.com. CONTACT: Iris Shaffer (708) 799-6284 </p></p>
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		<title>Woman going through menopause if u dont take hormone replacements what do you take for ur symptoms?</title>
		<link>http://symptomadvice.com/woman-going-through-menopause-if-u-dont-take-hormone-replacements-what-do-you-take-for-ur-symptoms/</link>
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		<pubDate>Thu, 23 Dec 2010 19:51:11 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[hormone symptoms]]></category>
		<category><![CDATA[british medical journal]]></category>
		<category><![CDATA[fatigue]]></category>
		<category><![CDATA[insomnia]]></category>
		<category><![CDATA[menopausal symptoms]]></category>
		<category><![CDATA[natural approaches]]></category>
		<category><![CDATA[new england journal]]></category>

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		<description><![CDATA[Have &#121;&#111;&#117; &#116;&#114;&#105;&#101;&#100; Dont Pause &#097;&#108;&#108; natural supplement? I haven&#039;t &#116;&#114;&#105;&#101;&#100; Don&#039;t Pause, but I &#104;&#097;&#118;&#101; &#116;&#114;&#105;&#101;&#100; many other natural approaches &#102;&#111;&#114; &#109;&#121; menopausal symptoms. I &#104;&#097;&#118;&#101; changed &#109;&#121; diet, used herbs and other natural supplements &#102;&#111;&#114; hot flashes, insomnia, mood swings, fatigue, anxiety and heart health. To learn more about specific herbs and vitamins [...]]]></description>
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<p>Have &#121;&#111;&#117; &#116;&#114;&#105;&#101;&#100; Dont Pause &#097;&#108;&#108; natural supplement?</p>
<p>I haven&#039;t &#116;&#114;&#105;&#101;&#100; Don&#039;t Pause, but I &#104;&#097;&#118;&#101; &#116;&#114;&#105;&#101;&#100; many other natural approaches &#102;&#111;&#114; &#109;&#121; menopausal symptoms. I &#104;&#097;&#118;&#101; changed &#109;&#121; diet, used herbs and other natural supplements &#102;&#111;&#114; hot flashes, insomnia, mood swings, fatigue, anxiety and heart health. To learn more about specific herbs and vitamins &#102;&#111;&#114; specific symptoms, visit natural-approaches-to-menopau…</p>
<p>Some women say &#116;&#104;&#097;&#116; Soy products &#104;&#101;&#108;&#112;, &#108;&#105;&#107;&#101; drinking Soy milk. It &#105;&#115; supposed to &#104;&#101;&#108;&#112; &#119;&#105;&#116;&#104; the hot flashes.</p>
<p>Hormone Replacement Therapy carries significant health risks. But &#116;&#104;&#101;&#114;&#101; &#105;&#115; &#097; natural option.<br /> As reported by Lancelot, the British Medical Journal, Hormone Replacement Therapy {HRT} increases &#097; woman&#039;s chance &#111;&#102; getting ovarian cancer by 20%. <br /> &#105;&#110; the U.S, between 2001 and 2004, cases &#111;&#102; breast cancer dropped 8.6% among women general population.<br /> And what&#039;s &#101;&#118;&#101;&#110; more interesting &#105;&#115; &#116;&#104;&#097;&#116; among women 50 and older, the drop &#119;&#097;&#115; &#101;&#118;&#101;&#110; greater- 11.8%! <br /> Why &#105;&#115; this? <br /> Well, &#098;&#101;&#099;&#097;&#117;&#115;&#101; &#097; good number &#111;&#102; women STOPPED Hormone Replacement Therapy{HRT}.<br /> Who said &#116;&#104;&#097;&#116;, &#121;&#111;&#117; ask? <br /> &#110;&#111; less &#097;&#110; authority than &quot;The New England Journal &#111;&#102; Medicine&quot;, that&#039;s &#119;&#104;&#111;!<br /> &#105;&#110; layman {laywoman?} language, &#119;&#104;&#097;&#116; &#100;&#111;&#101;&#115; this &#109;&#101;&#097;&#110;? <br /> It means &#116;&#104;&#097;&#116; &#116;&#104;&#101;&#114;&#101; &#119;&#101;&#114;&#101; 30,000 &#102;&#101;&#119;&#101;&#114; incidences &#111;&#102; breast cancer during 2001-2004! <br /> You &#119;&#111;&#117;&#108;&#100; remember &#116;&#104;&#097;&#116; this good news, &#098;&#101;&#099;&#097;&#117;&#115;&#101; &#111;&#102; its health significance, &#119;&#097;&#115; broadcast over &#101;&#118;&#101;&#114;&#121; Television channel, &#114;&#105;&#103;&#104;&#116;? <br /> WRONG!<br /> Who &#108;&#111;&#111;&#107;&#115; &#111;&#117;&#116; &#102;&#111;&#114; &#121;&#111;&#117;? &#121;&#111;&#117;, that&#039;s &#119;&#104;&#111;. Your health &#105;&#115; your responsibility.<br /> Here &#105;&#115; &#097; natural option: bit.ly/9gr8Hf</p></p>
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		<title>Relieve Hormonal Signs And Symptoms Of Menopause With A Natural Meals Diet</title>
		<link>http://symptomadvice.com/relieve-hormonal-signs-and-symptoms-of-menopause-with-a-natural-meals-diet/</link>
		<comments>http://symptomadvice.com/relieve-hormonal-signs-and-symptoms-of-menopause-with-a-natural-meals-diet/#comments</comments>
		<pubDate>Sun, 05 Dec 2010 21:00:29 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[hormone symptoms]]></category>
		<category><![CDATA[menopausal symptoms]]></category>
		<category><![CDATA[mood swings]]></category>
		<category><![CDATA[post menopausal]]></category>

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		<description><![CDATA[Seeking far &#109;&#111;&#114;&#101; natural ways to &#104;&#101;&#108;&#112; with &#116;&#104;&#101; symptoms of menopause? &#113;&#117;&#105;&#116;&#101; &#097; few herbal treatments &#099;&#097;&#110; relieve &#097;&#110;&#100; even eliminate &#116;&#104;&#101; prevalent symptoms of these circumstances. Throughout menopause, women frequently expertise uncomfortable symptoms. &#118;&#101;&#114;&#121; hot flashes, evening sweats, mood swings, irregular, modifications &#105;&#110; bleeding &#097;&#110;&#100; loss of sexual desire are &#097; few of [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2010/12/1291582829-48.jpg%3Fw%3D560%26h%3D372" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" />
<p>Seeking far &#109;&#111;&#114;&#101; natural ways to &#104;&#101;&#108;&#112; with &#116;&#104;&#101; symptoms of menopause? &#113;&#117;&#105;&#116;&#101; &#097; few herbal treatments &#099;&#097;&#110; relieve &#097;&#110;&#100; even eliminate &#116;&#104;&#101; prevalent symptoms of these circumstances. </p>
<p>Throughout menopause, women frequently expertise uncomfortable symptoms. &#118;&#101;&#114;&#121; hot flashes, evening sweats, mood swings, irregular, modifications &#105;&#110; bleeding &#097;&#110;&#100; loss of sexual desire are &#097; few of &#116;&#104;&#101; &#109;&#111;&#115;&#116; prevalent. Not &#116;&#111;&#111; long ago, studies have demonstrated that hormone replacement treatment isn&#8217;t &#097;&#115; secure &#097;&#115; originally considered, so numerous women are searching to natural treatments having &#097; wonderful deal of accomplishment. </p>
<p>Black cohosh has &#098;&#101;&#101;&#110; employed &#102;&#111;&#114; hundreds of years to &#104;&#101;&#108;&#112; women with menopausal symptoms, &#097;&#110;&#100; &#105;&#115; &#109;&#111;&#115;&#116; efficient &#105;&#110; treating &#118;&#101;&#114;&#121; hot flashes. It appears to get some capacity to imitate estrogen &#105;&#110; &#116;&#104;&#101; body, relieving &#116;&#104;&#101; &#118;&#101;&#114;&#121; hot flashes &#097;&#110;&#100; mood swings that plague so numerous women. </p>
<p>Limiting caffeine &#119;&#105;&#108;&#108; &#104;&#101;&#108;&#112; with &#121;&#111;&#117;&#114; symptoms &#116;&#111;&#111;. Natural teas, &#097;&#110;&#100; making &#117;&#115;&#101; of onion, garlic &#097;&#110;&#100; lemon &#105;&#110;&#115;&#116;&#101;&#097;&#100; of salt &#114;&#101;&#097;&#108;&#108;&#121; &#115;&#104;&#111;&#117;&#108;&#100; &#104;&#101;&#108;&#112; &#116;&#111;&#111;. One research at UCLA noted that garlic halted &#116;&#104;&#101; advance of heart illness &#105;&#110; post-menopausal women. </p>
<p>Soy, demonstrated to be useful &#105;&#110; so numerous regions, assists with menopausal symptoms &#116;&#111;&#111;. Soy includes &#097; natural estrogen-like compound that assists balance hormones. Chickpeas, lentils &#097;&#110;&#100; tofu &#119;&#105;&#108;&#108; offer &#116;&#104;&#101; same benefits. Complex carbohydrates &#108;&#105;&#107;&#101; brown rice &#119;&#105;&#108;&#108; even &#104;&#101;&#108;&#112; regulate &#116;&#104;&#101; amount of estrogen &#105;&#110;&#115;&#105;&#100;&#101; &#121;&#111;&#117;&#114; program. </p>
<p>Making &#099;&#101;&#114;&#116;&#097;&#105;&#110; that &#121;&#111;&#117; &#109;&#105;&#103;&#104;&#116; be receiving &#097; sufficient amount of essential fatty acids &#098;&#121; eating oils, nuts, seeds &#097;&#110;&#100; oily fish &#119;&#105;&#108;&#108; &#104;&#101;&#108;&#112; relieve vaginal dryness &#097;&#110;&#100; keep &#116;&#104;&#101; pores &#097;&#110;&#100; skin supple. </p>
<p>Much &#109;&#111;&#114;&#101; &#097;&#110;&#100; far &#109;&#111;&#114;&#101; women are searching &#102;&#111;&#114; choice therapies &#102;&#111;&#114; symptoms of menopause. Attempt these easy &#097;&#110;&#100; natural foods treatments these days.Menopause &#104;&#101;&#108;&#112; &#102;&#111;&#114; &#116;&#104;&#111;&#115;&#101; &#105;&#110; need </p></p>
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