I've been on EFFEXOR XR 300 mg for about two months now. are mood, concentration, focus the last symptoms to improve?

Beside medicine, you can use the following strategies
Perhaps you should follow this strategies:
Step 1: Ensure your emotion is controlled daily. Don't over reacted, stay calm and don't get depress and angry easily
Step 2: Think before your action. Don't repeat your past experience on yourselve
Step 3: Be confident to yourselves. Remember everyone is the winner. "Only One sperms out of millions fertilize a eggs"
Step 4: Get a group of close friends to share your experience and get some activities that would occupied your time
Good Luck.
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You know the meds work different and in different ways for everyone. I hope you are getting some therapy along with your medication.

I also suffer from depression with manic episodes (bipolar). I have spent many years and have changed psychatrists (when they no longer were listening to me or were fustrated and didn't seem to want to help) before I found a solution to my problem.

First, after being on an antidepressant for two months or more, the drug should have given a person some indication of improvement. As others have suggested, talk to your doctor. If it seems that he or she doesn't want to listen to you or wants to cram something down your throat that isn't working, seek a new doctor.

Second, other medications may be necessary to compliment your current medication. I am currently taking 3 different medications (down from 5) that in harmony is helping me. Discuss this with your doctor also.

Third, as others have responded to your question said, seek out therapy. Medication will take care of any chemical unbalance in the brain. Cognitive therapy compliments the medication by helping a person understand and deal with thinking that helped to produce the disorder. my counsler is very good because she listens to me and respects my beliefs and philosophy.

Finally, and this is a personal one for me, set up a support network. Include family, friends, and clergy. Be patient with this one. People will have a hard time understanding the situation, especially if they knew you before you discovered this disorder. I say that this is personal because it all depends on your religion and what you believe about God. For me, I believe I couldn't have gotten as far in recovering as I have if it wasn't for prayers and my faith and trust in God.