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	<title>Symptom Advice .com &#187; pyrimethamine</title>
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		<title>Reduce Risk of p.falciparum</title>
		<link>http://symptomadvice.com/reduce-risk-of-p-falciparum/</link>
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		<pubDate>Mon, 25 Apr 2011 21:17:10 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[malaria symptoms]]></category>
		<category><![CDATA[fever]]></category>
		<category><![CDATA[hiv]]></category>
		<category><![CDATA[ipt]]></category>
		<category><![CDATA[malaria]]></category>
		<category><![CDATA[pyrimethamine]]></category>
		<category><![CDATA[trimesters]]></category>

		<guid isPermaLink="false">http://symptomadvice.com/reduce-risk-of-p-falciparum/</guid>
		<description><![CDATA[I &#119;&#111;&#117;&#108;&#100; &#108;&#105;&#107;&#101; to add a few more details to &#116;&#104;&#101; response above. Intermittent Prevetive Treatment for pregnant women (IPTp) &#105;&#115; &#101;&#115;&#112;&#101;&#099;&#105;&#097;&#108;&#108;&#121; relevant for women &#119;&#104;&#111; have lived &#097;&#110;&#100; continue to live in areas with malaria. &#116;&#104;&#101;&#121; generally have been exposed to malaria before, &#097;&#110;&#100; in many cases malaria has been detected in &#116;&#104;&#101;&#105;&#114; placentas, [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/04/1303766230-17.jpg" style="clear:both;clear:both;margin:0 15px 15px 0;width:500px" />
<p>I &#119;&#111;&#117;&#108;&#100; &#108;&#105;&#107;&#101; to add a few more details to &#116;&#104;&#101; response above. Intermittent Prevetive Treatment for pregnant women (IPTp) &#105;&#115; &#101;&#115;&#112;&#101;&#099;&#105;&#097;&#108;&#108;&#121; relevant for women &#119;&#104;&#111; have lived &#097;&#110;&#100; continue to live in areas with malaria. &#116;&#104;&#101;&#121; generally have been exposed to malaria before, &#097;&#110;&#100; in many cases malaria has been detected in &#116;&#104;&#101;&#105;&#114; placentas, but &#116;&#104;&#101;&#121; can &#098;&#101; completely asymptomatic (i.e. &#116;&#104;&#101;&#121; have no symptoms) &#111;&#102; malaria &#108;&#105;&#107;&#101; fever etc. Researchers &#102;&#111;&#117;&#110;&#100; that giving a &#099;&#111;&#117;&#114;&#115;&#101; &#111;&#102; &#097;&#110; antimalarial treatment &#097;&#116; &#115;&#112;&#101;&#099;&#105;&#102;&#105;&#101;&#100; time points, reduced maternal anaemia &#097;&#110;&#100; &#116;&#104;&#101; likelihood &#111;&#102; having a &#108;&#111;&#119; birth weight baby.</p>
<p>The recommended schedule for IPT in pregnant women &#105;&#115; &#097;&#115; follows:</p>
<p>SP shall &#098;&#101; &#103;&#105;&#118;&#101;&#110; &#097;&#115; single adult dose (3 tablets &#111;&#102; 500mg Sulphadoxineand 25mg Pyrimethamine each) &#097;&#116; scheduled antenatal care visits during &#116;&#104;&#101; second &#097;&#110;&#100; &#116;&#104;&#105;&#114;&#100; trimesters.</p>
<p>The two doses &#111;&#102; SP shall &#098;&#101; &#103;&#105;&#118;&#101;&#110; &#097;&#116; &#108;&#101;&#097;&#115;&#116; one month apart.1st. Dose: &#097;&#116; &#116;&#104;&#101; first antenatal visit &#097;&#102;&#116;&#101;&#114; quickening (first fetal movement – &#102;&#114;&#111;&#109; sixteen weeks)2nd. Dose: &#097;&#116; &#108;&#101;&#097;&#115;&#116; one month &#097;&#102;&#116;&#101;&#114; &#116;&#104;&#101; first dose.</p>
<p>NOTE: HIV positive pregnant women shall receive &#097;&#116; &#108;&#101;&#097;&#115;&#116; 3 doses &#111;&#102; SP &#105;&#110;&#115;&#116;&#101;&#097;&#100; &#111;&#102; two doses (subsequent doses shall &#098;&#101; &#103;&#105;&#118;&#101;&#110; &#097;&#116; &#108;&#101;&#097;&#115;&#116; one month apart).</p>
<p>As &#116;&#104;&#101; editor mentioned, IPT &#105;&#115; &#097;&#108;&#115;&#111; recommended &#098;&#121; WHO, UNICEF &#097;&#110;&#100; other international organizations. &#116;&#104;&#101; following &#105;&#115; &#097;&#110; explanation &#111;&#102; IPT in infants.</p>
<p>What &#105;&#115; Intermittent Preventive Treatment &#111;&#102; malaria in infants (IPTi)?</p>
<p>IPTi &#105;&#115; &#116;&#104;&#101; administration &#111;&#102; &#097;&#110; antimalarial drug &#097;&#116; &#116;&#104;&#101; time &#111;&#102; childhood vaccinations in &#116;&#104;&#101; first year &#111;&#102; life &#097;&#110;&#100; takes advantage &#111;&#102; delivery &#097;&#108;&#111;&#110;&#103;&#115;&#105;&#100;&#101; &#116;&#104;&#101; well functioning WHO Expanded Programme for Immunisation (EPI). &#117;&#110;&#100;&#101;&#114; this approach, infants receive &#097;&#110; anti-malarial drug two or three times during &#116;&#104;&#101; first year &#111;&#102; life whether or &#110;&#111;&#116; &#116;&#104;&#101;&#121; have malaria &#097;&#110;&#100; are &#112;&#114;&#111;&#118;&#105;&#100;&#101;&#100; with prophylactic protection for &#116;&#104;&#101; duration &#116;&#104;&#101; anti-malaria drug &#105;&#115; present in &#116;&#104;&#101; blood.</p>
<p>Why IPTi &#105;&#110;&#115;&#116;&#101;&#097;&#100; &#111;&#102; chemoprophylaxis?</p>
<p>Continuous chemoprophylaxis in young children reduces malaria morbidity during &#116;&#104;&#101; period &#111;&#102; prophylaxis, &#104;&#111;&#119;&#101;&#118;&#101;&#114; following &#116;&#104;&#101; cessation &#111;&#102; prophylaxis, a rebound &#111;&#102; malaria was noted in &#116;&#104;&#101; treatment group (Greenwood 1995, Menendez 1997), even though it &#105;&#115; uncertain whether &#116;&#104;&#101;&#115;&#101; children &#097;&#099;&#116;&#117;&#097;&#108;&#108;&#121; experienced more malaria &#116;&#104;&#097;&#110; &#116;&#104;&#101; children that received placebo &#119;&#104;&#101;&#110; &#116;&#104;&#101; &#119;&#104;&#111;&#108;&#101; period &#097;&#116; risk was taken &#105;&#110;&#116;&#111; account. Menendez &#101;&#116; al gave weekly chemoprophylaxis to infants &#102;&#114;&#111;&#109; 2 to 12 months &#111;&#102; age which &#112;&#114;&#111;&#118;&#105;&#100;&#101;&#100; 60% protective efficacy against clinical malaria, &#104;&#111;&#119;&#101;&#118;&#101;&#114; &#116;&#104;&#101;&#115;&#101; children &#116;&#104;&#101;&#110; experienced almost double &#116;&#104;&#101; level &#111;&#102; clinical malaria &#116;&#104;&#097;&#110; &#116;&#104;&#101; placebo group &#119;&#104;&#101;&#110; &#116;&#104;&#101; prophylaxis was stopped. &#119;&#104;&#101;&#110; &#116;&#104;&#101; children were followed up to 4 years &#111;&#102; age &#116;&#104;&#101; &#097;&#109;&#111;&#117;&#110;&#116; &#111;&#102; malaria experienced &#098;&#121; &#116;&#104;&#101; two groups was similar (Aponte 2007). Due to &#116;&#104;&#101; concern &#111;&#102; a rebound in malaria, &#097;&#110;&#100; &#098;&#101;&#099;&#097;&#117;&#115;&#101; &#111;&#102; &#116;&#104;&#101; major logistic challenges involved in delivering weekly prophylaxis, &#097;&#110;&#100; fears that large-scale drug &#117;&#115;&#101; &#119;&#111;&#117;&#108;&#100; hasten &#116;&#104;&#101; spread &#111;&#102; drug resistance, implementation did &#110;&#111;&#116; occur in endemic countries.</p>
<p>How has Intermittent Preventive Treatment (IPT) developed &#097;&#115; a treatment?</p>
<p>Continuous chemoprophylaxis was recommended for pregnant women to decrease &#116;&#104;&#101; deleterious affects &#111;&#102; malaria during pregnancy such &#097;&#115; maternal anaemia resulting in &#108;&#111;&#119; birth weight babies vulnerable to other infections. &#104;&#111;&#119;&#101;&#118;&#101;&#114;, problems &#111;&#102; delivery &#111;&#102; &#116;&#104;&#101; anti-malarial drug &#097;&#110;&#100; compliance &#111;&#102; &#116;&#104;&#101; woman taking &#116;&#104;&#101; anti-malarial drug &#111;&#110; a regular basis greatly reduced &#116;&#104;&#101; effectiveness &#111;&#102; this strategy. &#104;&#111;&#119;&#101;&#118;&#101;&#114;, high levels &#111;&#102; African women visit antenatal clinics during &#116;&#104;&#101;&#105;&#114; pregnancy &#097;&#110;&#100; it was demonstrated that, delivery &#111;&#102; a full &#099;&#111;&#117;&#114;&#115;&#101; &#111;&#102; &#097;&#110; antimalarial treatment &#097;&#116; &#115;&#112;&#101;&#099;&#105;&#102;&#105;&#101;&#100; time points &#114;&#101;&#103;&#097;&#114;&#100;&#108;&#101;&#115;&#115; &#111;&#102; &#116;&#104;&#101; presence &#111;&#102; parasites, reduced maternal anaemia &#097;&#110;&#100; &#116;&#104;&#101; likelihood &#111;&#102; having a &#108;&#111;&#119; birth weight baby – &#097;&#110;&#100; &#116;&#104;&#101; WHO recommends &#116;&#104;&#101; &#117;&#115;&#101; &#111;&#102; IPT in pregnancy (IPTp) for malaria control.</p>
<p>With &#116;&#104;&#101; success in preventing malaria morbidity &#117;&#115;&#105;&#110;&#103; IPTp, it was &#100;&#101;&#099;&#105;&#100;&#101;&#100; to investigate IPT in infants (IPTi), taking advantage &#111;&#102; &#116;&#104;&#101; regular contacts that babies have with &#116;&#104;&#101; clinic in &#116;&#104;&#101; first year &#111;&#102; life &#119;&#104;&#101;&#110; &#116;&#104;&#101;&#105;&#114; caregivers bring &#116;&#104;&#101;&#109; in to receive vaccinationas delievered &#116;&#104;&#114;&#111;&#117;&#103;&#104; &#116;&#104;&#101; WHO’s Expanded Programme for Immunisation (EPI).</p>
<p>First results for IPTi:A study conducted in Ifakara, Tanzania &#111;&#102; IPTi with sulfadoxine-pyrimethamine (SP), delivered &#097;&#116; &#116;&#104;&#101; time &#111;&#102; &#116;&#104;&#101; second &#097;&#110;&#100; &#116;&#104;&#105;&#114;&#100; doses &#111;&#102; Diptheria-Tetanus-Pertussis/Oral Poliovirus Vaccine (DTP/OPV) &#097;&#110;&#100; measles vaccination, &#097;&#116; approximately 2, 3 &#097;&#110;&#100; 9 months &#111;&#102; age resulted in a 59% reduction in &#116;&#104;&#101; incidence &#111;&#102; clinical malaria &#097;&#110;&#100; a 50% reduction in &#116;&#104;&#101; incidence &#111;&#102; severe anaemia (a PCV &lt; 25%) in &#116;&#104;&#101; first year &#111;&#102; life (Schellenberg &#101;&#116; al Lancet 2001). Infants &#119;&#104;&#111; received IPTi-SP were &#097;&#108;&#115;&#111; less likely to present &#097;&#115; outpatients with fever &#097;&#110;&#100; less likely to &#098;&#101; admitted. Safety monitoring suggested no adverse consequences &#111;&#102; IPTi-SP &#097;&#110;&#100; serological analysis &#111;&#102; &#116;&#104;&#101; response to routine vaccinations was &#097;&#108;&#115;&#111; reassuring. Infants &#119;&#104;&#111; received IPTi-SP &#097;&#108;&#115;&#111; &#104;&#097;&#100; 36% less malaria in &#116;&#104;&#101; second year &#111;&#102; life (Schellenberg &#101;&#116; al Lancet 2005).</p>
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		<item>
		<title>My friend got a malaria symptom, is there a cure for it????</title>
		<link>http://symptomadvice.com/my-friend-got-a-malaria-symptom-is-there-a-cure-for-it/</link>
		<comments>http://symptomadvice.com/my-friend-got-a-malaria-symptom-is-there-a-cure-for-it/#comments</comments>
		<pubDate>Tue, 11 Jan 2011 02:34:11 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[malaria symptoms]]></category>
		<category><![CDATA[begining]]></category>
		<category><![CDATA[malaria]]></category>
		<category><![CDATA[primaquine]]></category>
		<category><![CDATA[pyrimethamine]]></category>

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		<description><![CDATA[I&#039;ll &#098;&#101; thanlfull for &#097;&#110;&#121; help Actually&#8230;d &#098;&#101;&#115;&#116; thing 2 do &#105;&#115; 2 go &#115;&#101;&#101; a doctor&#8230;coz u can&#039;t &#098;&#101; sure if it&#039;s just a sickness &#111;&#114; it&#039;s really a begining of malaria&#8230; Malarial paracite test &#111;&#102;&#116;&#101;&#110; &#099;&#111;&#109;&#101;&#115; negative in the patients suffering form Malaria. &#121;&#111;&#117; &#099;&#097;&#110; &#118;&#101;&#114;&#121; safely &#116;&#097;&#107;&#101; a course of cloroquine (Lariago) [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="http://symptomadvice.com/wp-content/uploads/2011/01/1294713252-22.jpg" style="clear:both;clear:both;margin:0 15px 15px 0" />
<p> <img src='http://symptomadvice.com/wp-includes/images/smilies/icon_sad.gif' alt=':(' class='wp-smiley' />  I&#039;ll &#098;&#101; thanlfull for &#097;&#110;&#121; help</p>
<p>Actually&#8230;d &#098;&#101;&#115;&#116; thing 2 do &#105;&#115; 2 go &#115;&#101;&#101; a doctor&#8230;coz u can&#039;t &#098;&#101; sure if it&#039;s just a sickness &#111;&#114; it&#039;s really a begining of malaria&#8230;</p>
<p>Malarial paracite test &#111;&#102;&#116;&#101;&#110; &#099;&#111;&#109;&#101;&#115; negative in the patients suffering form Malaria. &#121;&#111;&#117; &#099;&#097;&#110; &#118;&#101;&#114;&#121; safely &#116;&#097;&#107;&#101; a course of cloroquine (Lariago) which lasts for 5 days and at the end of &#105;&#116; your friend may feel a lot of weakness that &#119;&#105;&#108;&#108; go with time</p>
<p>cure for malaria &#105;&#115; &#118;&#101;&#114;&#121; near your hand.<br /> medicine like chloroquine, quinine, pyrimethamine/sulphadoxine, artemisinin, primaquine are given. </p>
<p> take your friend to a doctor.</p></p>
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