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	<title>Symptom Advice .com &#187; robert belshe</title>
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		<title>Experimental herpes vaccine disappoints in study</title>
		<link>http://symptomadvice.com/experimental-herpes-vaccine-disappoints-in-study/</link>
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		<pubDate>Fri, 06 Jan 2012 17:17:12 +0000</pubDate>
		<dc:creator>Symptom Advice</dc:creator>
				<category><![CDATA[std symptoms]]></category>
		<category><![CDATA[dr robert]]></category>
		<category><![CDATA[herpes]]></category>
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		<category><![CDATA[journal of medicine]]></category>
		<category><![CDATA[robert belshe]]></category>
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		<description><![CDATA[(Credit:istockphoto) (CBS) An experimental herpes vaccine failed to protect young women from the disease in &#097; &#110;&#101;&#119; study, dashing hopes that &#097; vaccine may soon &#098;&#101; available to &#104;&#101;&#108;&#112; prevent the sexually transmitted disease. PICTURES: Bogus STD cures: &#097;&#114;&#101; &#121;&#111;&#117; taking &#111;&#110;&#101;? In &#097; study of 8,300 women ages 18 to 30, the vaccine, developed [...]]]></description>
			<content:encoded><![CDATA[<p></p><p><img src="" style="float:left;clear:both;margin:0 15px 15px 0" />(Credit:istockphoto) </p>
<p>(CBS) An experimental herpes vaccine failed to protect young women from the disease in &#097; &#110;&#101;&#119; study, dashing hopes that &#097; vaccine may soon &#098;&#101; available to &#104;&#101;&#108;&#112; prevent the sexually transmitted disease.</p>
<p>PICTURES: Bogus STD cures: &#097;&#114;&#101; &#121;&#111;&#117; taking &#111;&#110;&#101;?</p>
<p>In &#097; study of 8,300 women ages 18 to 30, the vaccine, developed by GlaxoSmithKline, partially protected &#097;&#103;&#097;&#105;&#110;&#115;&#116; HSV-1, the strain of herpes which typically causes cold sores but can also &#099;&#097;&#117;&#115;&#101; genital herpes. The vaccine, however, did &#110;&#111;&#116; protect &#097;&#103;&#097;&#105;&#110;&#115;&#116; HSV-2, the strain that most commonly causes genital herpes.</p>
<p>&#8220;There is &#115;&#111;&#109;&#101; &#118;&#101;&#114;&#121; good news in &#111;&#117;&#114; findings. We were partially successful &#097;&#103;&#097;&#105;&#110;&#115;&#116; half of the equation &#8211; protecting women from genital disease caused by HSV-1,&#8221; study author Dr. Robert Belshe, director of the Saint Louis University Center &#102;&#111;&#114; Vaccine Development, said in &#097; written statement.</p>
<p>None of the women had &#097;&#110;&#121; strain of herpes &#119;&#104;&#101;&#110; the study &#098;&#101;&#103;&#097;&#110;, &#097;&#110;&#100; half of the women were &#103;&#105;&#118;&#101;&#110; the experimental vaccine while the other half were &#103;&#105;&#118;&#101;&#110; &#097; hepatitis &#097; vaccine. Doctors monitored the women &#102;&#111;&#114; twenty months, &#097;&#110;&#100; throughout the study, &#115;&#111;&#109;&#101; women &#103;&#111;&#116; herpes.&nbsp; The experimental vaccine was 58 percent effective &#097;&#116; preventing genital herpes from HSV-1, but did &#110;&#111;&#116; &#115;&#104;&#111;&#119; protection &#097;&#103;&#097;&#105;&#110;&#115;&#116; HSV-2. The study was published in the Jan. 5 issue of the New England Journal of Medicine. </p>
<p>Belshe said in the statement he was surprised the vaccine protected &#097;&#103;&#097;&#105;&#110;&#115;&#116; &#111;&#110;&#101; type of vaccine &#097;&#110;&#100; &#110;&#111;&#116; the other, but thinks that finding &#099;&#111;&#117;&#108;&#100; lead to &#109;&#111;&#114;&#101; research to &#098;&#101;&#116;&#116;&#101;&#114; understand the disease.</p>
<p>&#8220;This is &#110;&#111;&#116; the final vaccine,&#8221; Belshe told WebMD. &#8220;This information will &#104;&#101;&#108;&#112; &#117;&#115; &#097; lot.&#8221;</p>
<p>Some experts aren&#8217;t &#097;&#115; optimistic.</p>
<p>&#8220;I was &#118;&#101;&#114;&#121; disappointed there wasn&#8217;t &#109;&#111;&#114;&#101; of &#097; benefit,&#8221; Dr. Bruce Hirsch, an attending physician in infectious diseases &#097;&#116; North Shore University Hospital in Manhasset, N.Y., who wasn&#8217;t involved in the study, told HealthDay. &#8220;I&#8217;m concerned if we&#8217;ll &#101;&#118;&#101;&#114; &#102;&#105;&#110;&#100; &#097; vaccine effective &#102;&#111;&#114; HSV-2.&#8221;</p>
<p>&#8220;Enough vaccines &#104;&#097;&#118;&#101; failed that companies &#097;&#114;&#101; &#115;&#101;&#101;&#105;&#110;&#103; herpes vaccines &#097;&#115; &#097; risky business,&#8221; added Dr. David Knipe, &#097; virologist &#097;&#116; Harvard Medical School in Boston. Knipe told Nature News he thinks the public sector &#109;&#105;&#103;&#104;&#116; need to fund herpes vaccine research to &#102;&#117;&#114;&#116;&#104;&#101;&#114; advance it.</p>
<p>More than 50 million U.S. adults &#104;&#097;&#118;&#101; herpes, &#097;&#099;&#099;&#111;&#114;&#100;&#105;&#110;&#103; to WebMD, with up to 1.6 &#110;&#101;&#119; infections occurring each year. Abstinence is the only way to prevent the STD, &#097;&#110;&#100; latex condoms can reduce the risk of transmission, but the disease &#115;&#116;&#105;&#108;&#108; can spread with condom use. The CDC says persons with herpes should abstain from sexual activity with uninfected partners &#119;&#104;&#101;&#110; lesions or other symptoms &#097;&#114;&#101; present. But even &#119;&#105;&#116;&#104;&#111;&#117;&#116; symptoms, herpes can &#115;&#116;&#105;&#108;&#108; spread to &#097; partner. </p>
<p>The CDC has more &#111;&#110; genital herpes.</p></p>
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