Vitamin a supplements could reduce the risk of developing the deadly skin cancer melanoma, according to a new study.

The results show that people takingvitamin a were 60 percent less likely to develop melanoma over the six-year study. People who had taken the vitamin, but weren’t currently taking it, did not gain any protective effect. 

The reduced risk was more pronounced in women than men.

“This is promising evidence that in addition to sun protection, there’s another option that can help prevent melanoma,” said Dr. Mary Gail Mercurio, a dermatologist at the University of Rochester Medical Center, who was not involved with the study.  

Vitamin a is found in foods such as sweet potato, carrots, spinach, milk, eggs and liver. The vitamin plays an important role in vision, bone health, immune function and reproduction, but high doses of it can be toxic. 

The study appears today (March 1) in the Journal of Investigative Dermatology.

Genetics could increase melanoma risk

Melanoma is the sixth leading cause of cancer in the U.S., according to the American Cancer Society. About 76,000 cases of melanomas will be diagnosed this year, based on recent estimates.

In the study, researchers examined about 69,000 men and women, and after about six years, 566 had developed melanoma.

Among the 59,000 people in the study who had never taken vitamin a supplements, there were 506 cases of melanoma, while among the 5,800 people who were currently taking it and had used it regularly over the past 10 years, there were 28 cases.

Study researcher Dr. Maryam Asgari, a dermatologist and research scientist at Kaiser Permanente in Oakland, said the protective effect might be stronger in women than men because men may be more susceptible to skin damage from ultraviolet radiation.

She pointed to a recent animal study that suggests females may have more natural antioxidant protection in the skin than males.

The new study also found the melanoma risk was reduced the most in those who took high doses of the supplement. But Asgari cautioned that takingtoo much vitamin a could lead to such harmful conditions   as birth defects, liver problems and bone loss.

“There are limits to how much vitamin a a person can consume,” she said.

The recommended daily amount of vitamin a is 700 micrograms for adult women and 900 micrograms for adult men, according to the National Institutes of Health. Taking more than 2,800 micrograms of vitamin a could lead to toxic symptoms in adults.

Genetic risk

Reducing sunlight exposure has long been recommended to reduce the risk of melanoma. this includes limiting time in direct sunlight, wearing sun block and avoiding tanning beds. 

Unfortunately, not all melanoma is a result of sun exposure. there is also a strong genetic component, Mercurio said. “Even the most vigilant sun-avoider is at risk, especially if they are fair-skinned, freckle easily and have red or blonde hair.”

Although she said the study’s findings were compelling, she cautioned it’s not clear how much vitamin a might bring a benefit.

“We don’t know yet the optimal dosage,” Mercurio said. “Further studies will clarify how much vitamin a in the form of a supplement would be of benefit for melanoma prevention.” 

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No known food posioning, lack of sun protection and playing in paddling pool all afternoon. have been given diagnosis but want to double check.

go back to the doctor, as far as I know, thats not normal.

What a stupid question!!
He's got sunstroke!!!!!!!!!!!! Take him to you doctor, or better still, casualty.

honestly, it sounds like he has a bowel obstruction…..is his vomiting a bile color. get a second opion from a different doc though if you dont trust this one.

could have swallowed some water from the pool and caught a bug or maybe just eaten something he was allergic to

Appy or bowel obstruction. those would be worse case scenario. Severe constipation or the GI flu might be more realistic.

Take him to the doctor or hospital asap.

LoL XxX

no one can diagnose like this, if you dont trust your dr get another professional opinion after a face to face consultation.

Most likely constipation but take him to the pediatrician because you never know. he couldve also picked up some nasty virus in the pool, it happens all the time.

See your doctor and ask questions if not understand. if not happy with diagnosis see another doctor in your practice. do you live near a drop in centre call NHS you cannot take chances.

sounds like some random infection. Does he have a fever too? Any difficulty breathing. if so take him to the nearest hospital immediately !!!

it could be sun stroke , or has he been drinking the water from the pool,

either it is canstapation or sumtimes (i know this sonds horrible) but my kids are at school and they told me over the table that sumtimes poo can get on the outside of the intestine and then it swells up and you get the symptoms you have written in your question!!
hope your son gets better soonxxxxxxxxxx

xxxxxxx

Could be a hernia. Dont get second opinions on the internet!