What mutation causes Cystic Fibrosis?

by Symptom Advice on December 3, 2010

Can you also explain where on the chromosome the mutated gene is found?
How the mutation causes physical symptoms?
If the gene is recessive, do both alleles have to be recessive or do both alleles have to be heterozygous and have a 3:1 chance or homozygous and 4:0 chance.

CFTR mutation, affects sodium chloride channel function, is amplitude related. go to CFF.org or cfww.org , sticky mucus entraps bacteria, pseudomonas (in soil/spoiled lettuce, standing water/hot tubs) which is hard to eradicate once colonized, haemophilus non influenza and staph, sometimes MRSA infections, yeast infections, worst is cepacia (which is onion rot) some kids have other syndromes, downs, aspergers and autism in addition to CF. CF affects liver, pancreas (CFRD diabetes) GI tract (malabsorption syndrome/failure to thrive)search genetics of cystic fibrosis, secondary effects of cystic fibrosis. I have it.

Go to this website all of your answers will hopefully be there

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